Building Blocks

<p>Applications 5-Nitroisoquinoline (cas# 607-32-9) is a compound useful in organic synthesis.<br></p>

<p>Applications Methyl chlorodifluoroacetate<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 3-Hydroxypropionitrile (cas# 109-78-4) is a compound useful in organic synthesis.<br></p>

<p>Applications 10,12-TRICOSADIYNOIC ACID (cas# 66990-30-5) is a useful research chemical.<br></p>

<p>Stability Moisture Sensitive<br>Applications Triethyl orthopropionate is used as a starting material in the synthesis of Triethyl orthoacrylate. Triethyl orthopropionate is also commonly used in Claisen rearrangement reactions that yield γ,δ-unsaturated esters.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ghosh, A. &amp; Moon, D.: Org. Lett., 9, 2425 (2007); Ito, H. &amp; Taguchi, T.: Tetrahedron Lett., 38, 5829 (1997); Sarkar, D., et al.: Tetrahedron Lett., 50, 1431 (2009)<br></p>

<p>Applications: N'-Hydroxypyridine-3-carboximidamide<br></p>

<p>Applications 4,5-Dimethyl-o-phenylenediamine is used in biological processes as a substrate for CobT nicotinate-mononucleotide:5,6-dimethylbenzimidazole phosphoribosyltransferase from Salmonella typhimurium LT2.<br>References Trzebiatowski, J.R., et al.: J. Biol. Chem., 272, 17662 (1997); Johnson, M.G., et al., J. Biol. Chem., 267, 13302 (1992); Cheong, C., et al.: J. Biol. Chem., 277, 41120 (2002)<br></p>

<p>Applications N-(2-Indanyl)aniline is a reagent that is used in the synthesis of Aprindine Hydrochloride (A729900), which is a long-acting antiarrhythmic agent, effective when administered orally or intravenously in the treatment of ventricular arrhythmias of varying etiologies.<br>References Danilo, P. Jr., et al.: Am. Heart. J., 97, 119 (1979); Atarashi, H., et al.: Circulation. J., 66, 553 (2002);<br></p>

<p>Applications Dimethyl Malonate-d2 is an intermediate in the synthesis of Prasugrel Thiolactone-d5 (Mixture of Diastereomers). A labelled inactive metabolite of Prasugrel (P701150).<br>References Sugidachi, A., et al.: Br. J. Pharmacol., 129, 1439 (2000); Takahashi, S., et al.: J. Pharm. Sci., 97, 5434 (2008); Williams, E., et al.: Drug Metab. Dispos., 36, 1227 (2008); Hagihara, K., et al.: Xenobiotica, 39, 218 (2009);<br></p>

<p>Applications Hydrochloride salt of 2-Dimethylaminoisopropyl Chloride, used in the synthesis of analogues of lipophilic chalcones, which act as antitubercular agents.<br>References Ahmad, I. et al.: Bioorg. Med. Chem. Lett., 23, 1322 (2013); Rhee, H. et al.: Bull. Kor. Chem. Soc., 32, 2391 (2011);<br></p>

<p>Applications Sodium Naphthalene-2,6-disulfonate (cas# 1655-45-4) is a useful research chemical.<br></p>

<p>Applications 3-Iodoanisole (cas# 766-85-8) is a compound useful in organic synthesis.<br></p>

<p>Applications 2-Methoxyethylamine is used as a reagent in the preparation of lipid-like materials for delivery of RNAi therapeutics.<br>References Akinc, A., et al.: Nat. Biotechnol., 26, 561 (2008)<br></p>

<p>Applications Possess activity against positive phototaxis of Chlamydomonas cells.A fundamental starting material for organic synthesis.<br>References Evans, S., et al.: Chem. Biol. Drug. Des., 75, 333 (2010), Rajabi, L., et al.: Lett Appl Microbiol., 40, 212 (2005),<br></p>

<p>Applications 3,5-Diiodosalicylic Acid is an metabolite of Aspirin (A187780), an anti-inflammatory, anti-platelet and cancer-preventive agent. 3,5-Diiodosalicylic Acid was shown to exhibit agonist activity at GPR35, a orphan G protein coupled receptor.<br>References Deng, H.Y., et al.: Arch. Pharmacol., 385, 729 (2012); Blandin, V., et al.: Molec. Pharmacol., 58, 1461 (2000);<br></p>

<p>Applications Isobutyric Anhydride is used as a highly reactive and non-water producing acyl donor for hydrolase-catalyzed enantioselective esterification.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Xu, J.-H., et al.: Appl. Microbiol. Biot., 43, 402 (1995)<br></p>

<p>Applications 3-Bromopropionitrile acts as a reagent in the preparation of bisindole maleimide derivative useful as α-glucosidase inhibitors for the treatment of diabetesis. Also used in the study of the structure activity relations between alkyl nucleophilic chemicals causing duodenal ulcer and adrenocortical necrosis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Szabo, S., et al.: J. Pharm. Exp. Ther., 223, 68 (1982); Zhu, W., et al.: Faming Zhuanli Shenqing (2016); CN 106146487 A 20161123;<br></p>

<p>Applications 3-Methyl-3-(methylamino)butanoic Acid Methyl Ester is an derivative of substituted 3-pyrrolidinols with potential anticholinergic activities.<br>References Ryan, C.W., et al.; J. Org. Chem., 27, 2901 (1962);<br></p>

<p>Applications 2-Thiophenecarbonyl Chloride is used in the synthesis of substituted pyridines as selective and highly effective GPR119 agonists. It is also seen in the preparation of diuretics.<br>References Wu, Y. et al.: Bioorg. Med. Chem. Lett., 20, 2577 (2010); Plattner, J. et al.: J. Med. Chem., 27, 1016 (1984)<br></p>