Building Blocks

<p>Applications An antimicrobial agent used in cosmetic products.<br>References Liu, H., et al.: Chem. Res. Toxicol., 19, 1540 (2006), Roberts, W., et al.: J. Pharm. Sci., 90, 1318 (2001), Magnusson, B., et al.: J. Invest. Dermatol., 122, 993 (2004),<br></p>

<p>Stability Light Sensitive<br>Applications Dichlorodinitromethane is a derivative of nitromethane which is used in the preparation of Thermobaric explosives (TBX's).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Mohamed, A.K., Mostafa, H.E.: Int. Ann. Conf. ICT, 44th, 14 (2013)<br></p>

<p>Applications A non detergent sulfobetaine used as a mild solubilizing and stabilizing agent for halophilic malate dehydrogenase, halophilic elongation factor Tu (hTu), pig heart malate dehydrogenase, chicken egg white lysozyme and E. coli beta-galactosidase. Preserves the antigenic conformation of serine protease gp76. Does not interfere with colorimetric assays using p-nitrophenylphosphate and o-nitrophenyl-b-D-galactopyranoside as substrates. Reduces aggregation and significantly improves protein renaturation. Zwitterionic over a wide pH range. Does not absorb significantly in the near-UV range. Can be easily removed by dialysis.This compound is suitable for malate dehydrogenase (MDH) related research.<br>References Vuillard, L., et al.: Anal. Biochem., 230, 290 (1995); Vuillard, L., et al.: FEBS Lett., 353, 294 (1995); Vuillard, L., et al.: Biochem. J., 305, 337 (1995); Goldberg, M.E., et al.: Folding &amp; Design, 1, 21 (1996).<br></p>

<p>Stability Light Sensitive<br>Applications Cinnamyl alcohol is used as a fragrance ingredient and is a known a cause of allergic dermatitis in humans. Cinnamyl alcohol is also part of a group of cinnamic acid derivatives (for example: 4-Methoxycinnamic acid -M262150) that might be useful for the treatment of diabetes and obesity.<br>References Adisakwattana, S., et al.: J. Emzym. Inhib., 28, 1067, (2013); Basketter, D.: Acta-Derm.-Venereol., 72, 264 (1992); Letizia, C. S., et al.: Food Chem. Toxicol., 43, 837 (2005);<br></p>

<p>Applications Benznidazole (BNZ) is traditionally used to treat Chagas disease caused by Trypanosoma cruzi. The drugs used for the treatment of this disease, Nifurtimox and Benznidazole, are toxic and present severe side effects.<br>References Abuin, G., et al.: Mol. Biochem. Parasitol ., 35, 229 (1989), Arora, P., et al.: J. Biol. Chem., 270, 6042 (1995), Campos, M., et al.: J. Immunol., 167, 416 (2001), Faundez, M., et al.: Antimicrob. Agents Chemother., 49, 126 (2005),<br></p>

<p>Applications N-Nonanoylmorpholine (cas# 5299-64-9) is a useful research chemical.<br></p>

<p>Applications N-Fmoc-D-alanine is the N-Fmoc-protected form of D-Alanine (A480995). D-Alanine is an amino acid that is commonly found in bacteria, such as Streptococcus faecalis. It is essential for the biosynthesis of peptidoglycan crosslinking sub-units that are used for bacterial cell walls. D-Alanine is also known to cause cytotoxic oxidative stress in brain tumour cells.<br>References Ellsworth, B., et al.: Chem. Biol., 3, 37 (1996); Ferrari, E. et al.: Nat. Biotech., 3, 1003 (1985); Stegman, L., et al.: Human Gene Ther., 9, 185 (1998); Wood, W. &amp; Gunsalus, I.: J. Biol. Chem., 190, 403 (1951)<br></p>

<p>Applications Cinchophen and its derivatives can show antipyretic, analgesic, anti-oxidative, and anti-inflammatory properties.<br>References Xu, Bo., et al.: Beijing Yike Daxue Xuebao, 29(5), 438-439 (1997); Ibrahim, S. E., et al.: Mansoura J. Pharm. Sci., 6(2), 19-24 (1990); Mishra, Pradeep., et al.: Indian J. Pharm. Sci., 50(5), 269-271 (1988); Kononenko, L. I., et al.: Zhurnal Analiticheskoi Khimii, 30(9), 1716-19 (1975)<br></p>

<p>Impurity Loratadine USP Related Compound E<br>Applications Loratadine impurity. Loratidine impurity E. Loratadine USP Related Compound E.<br>References Villani, et al.: J. Med. Chem., 15, 750 (1972), Zhong, D., et al.: Pharmazie, 49, 736 (1994), Ruperez, F., et al.: J. Pharm. Biomed. Anal., 29, 35 (2002),<br></p>

<p>Applications Cinacalcet-d4 Hydrochloride is a labeled analogue of Cinacalcet Hydrochloride (C441800), the (R) enantiomer of Cinacalcet which is used in clinical trial in secondary hyperparathyroidism.<br>References Franceschini N., et al.: Expert Opin. Invest. Drugs, 12, 1413 (2003); Block, G.A., et al.: N. Engl. J. Med. 350, 1516 (2004);<br></p>

<p>Applications (R)-1-(3-Pyridyl)ethanol (cas# 7606-26-0) is a useful research chemical.<br></p>

<p>Applications Mono-Ethyl Malonate-1,2,3-13C3 (cas# 1189981-54-1) is a compound useful in organic synthesis.<br></p>

<p>Stability Hygroscopic<br>Applications A metabolite of Catecholamines.<br>References Kopin, I.J., et al.: J. Biol. Chem., 236, 2109 (1961), Short, F.W., et al.: J. Med. Pharm. Chem., 5, 642 (1962)<br></p>

<p>Applications Byproduct produced in the preparation of Atropine.<br></p>

<p>Applications Dimethylglyoxime is a chelating agent which forms complexes with metals such as copper, nickel, and palladium..<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications Polyoxyl 35 Castor Oil is a triglyceride fatty acid which has the potential to repel insects and promote plant growth.<br></p>

<p>Applications 2-(CHLOROMETHYL)NAPHTHALENE (cas# 2506-41-4) is a useful research chemical.<br></p>