Building Blocks

<p>Applications N-Methylmaleimide is an electron deficient olefin that acts as a thiol-blocking reagent in living human cells. N-Methylmaleimide also has the ability to undergo free-radical homopolymerization, and is used as a model for resins that contain the maleimide functional group.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sandreczki, T. &amp; Brown, I.: Macromolecules, 23, 1979 (1990); Shibata, A., et al.: Bioorg. Med. Chem. Lett., 18, 2246 (2008); Yin, J. &amp; Liebeskind, L.: J. Am. Chem. Soc., 121, 5811 (1999)<br></p>

<p>Applications 4-Thiouracil is a derivative of Uracil (U801000), which is a nitrogenous base in RNA nucleic acid. 4-Thiouracil is used for tagging in cell type-specific RNA isolation from intact complex tissues.<br>References Miller, M., et al.: Nat. Methods, 6, 439 (2009); Seth, P., et al.: J. Med. Chem., 53, 8309 (2010); Cui, H., et al.: Eur. J. Med. Chem., 45, 5140 (2010);<br></p>

<p>Applications DIBOA is an allelopathic biochemical that is produced by grasses. This benzoxazinoid compound displays health-promoting effects in rats.<br>References Adhikari, K. et al.: J. Agri. Food Chem., 60, 11518 (2012);<br></p>

<p>Applications 1-Iodoheptafluoropropane chain transfer agent; used in preparation method of binary Peroxyfluoro rubber and smart wearable material.<br>References Zhou, W., et al.: Faming Zhuanli Shenqing, (2020);<br></p>

<p>Applications 8-Bromo-1-octene, is a building block used for the synthesis of more complex pharmaceutical compounds, such as Dithienogermole (DTG) derivatives with varying alkyl chain lengths and pendant functionalities.<br>References Zong, K., et al.: Org. Lett., 15, 1032 (2013);<br></p>

<p>Applications Indole-2-carboxylic Acid (cas# 1477-50-5) is a compound useful in organic synthesis.<br></p>

<p>Applications 1,3-Dibromoadamantane (cas# 876-53-9) is a compound useful in organic synthesis.<br></p>

<p>Stability Unstable in solution<br>Applications Inhibits cancinogenesis at the initiation stage. A metabolite of 3-methylindole<br>References Stresser, D.M., et al.: J. Biochem. Toxicol., 10, 191 (1995), Bailey, G.S., et al.: J. Natl. Cancer Inst., 78, 931 (1987), D’Agostino et. al. Drug Metabolism and Disp. 27: 2018 (2009)<br></p>

<p>Stability Hygroscopic<br>Applications N,N,N'-Trimethyl-1,3-propanediamine is a reactant that as a ligand, racemizes aromatic alcohols completely in the prescence of a ruthenium-based racemization catalyst.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Riermeier, T.H., et. al.: Tetrahedron Lett., 46, 3403 (2005)<br></p>

<p>Applications Indole-3-acetamide is a compound that is converted to indole-3-acetic acid by indole-3-acetamide hydrolase in auxin biosynthesis in plants.<br>References Mano, Y., et al.: J. Exp. Bot., 61, 25 (2010)<br></p>

<p>Applications 4,4-diethylcyclohexan-1-amine hydrochloride (cas# 1087747-58-7) is a useful research chemical.<br></p>

<p>Applications trans-Indole-3-acrylic Acid is a regent used as a matrix for MALDI-TOF mass spectroscopy in order to characterize polyphenols.<br>References Madrigal-Carballo, S., et al.: Int Food Res J, 20, 2023-2034 (2013)<br></p>

<p>Applications Dimethyl Itaconate is a chemical reagent used in the synthesis of functionalized 2-isoxazolines used in fragment-based drug discovery.<br>References Tran, N. et al.: Tetrahedron Lett., 56, 4119 (2015); Louise Hazeland, E. et al.: Chem. Comm., 51, 10206 (2015);<br></p>

<p>Applications Iminostilbene-10,11-dihydrodiol is a metabolite of Carbamazepine 10,11-Epoxide (C175850).<br>References Belvedere, G. et al.: Res. Comm. Chem. Path. Pharmacol., 11, 221 (1975)<br></p>

<p>Applications (2E,6E)-3,7,11-Trimethyldodeca-2,6,10-trien-1-yl Acetate is an intermediate in the synthesis of JHSB3 (J211030). JHSB3 is an acyclic sesquiterpenoid that regulates many aspects of insect physiology. Juvenile Hormone regulate development, reproduction, diapause, and polyphenisms.<br>References Kotaki, T., et al.: Org. Let., 11, 5234 (2009); Riddiford, L.: Adv. Insect Physiol., 24, 213 (1994); Wyatt, G., Davey, K.: Adv. Insect Physiol., 26, 1 (1996); Nijhout, H.: Insect Hormones (Princeton Univ. Press, Princeton) (1994)<br></p>