Building Blocks

<p>Stability Hygroscopic<br>Applications Genetic incorporation of a metal-ion chelating amino acid into proteins as a biophysical probe.<br>References McRee, D., et al.: J. Struct. Biol., 125, 156 (1999), Wang, L., et al.: Science, 292, 498 (2001), Ioerger, T., et al.: Methods Enzymol., 374, 244 (2003),<br></p>

<p>Applications 2-Ethyl-2-methylpentanoic Acid is a derivative of 2,5-Dimethyl-2-ethylhexanoic Acid (D461540), used in biological studies to evaluate environmental chemicals for estrogenicity.<br>References Rabinowitz, J.R., et al.: Chem. Res. Toxicol.,22, 1594 (2009); Judson, R., et al.: Environ. Health Perspect, 117, 685 (2009)<br></p>

<p>Stability Moisture Sensitive<br>Applications 3A-METHYLHEXAHYDROISOBENZOFURAN-1,3-DIONE (cas# 25550-51-0) is a useful research chemical.<br></p>

<p>Applications 2-Phenylbenzothiazole is an organic compound that was detected in water and sediment from sedimentation ponds as a contaminant.<br>References Grung, M., et al.: Sci. Total Environ., 751, 141808 (2021)<br></p>

<p>Applications trans 3-(N-Methylanilino)acrolein (cas# 34900-01-1) is a compound useful in organic synthesis.<br></p>

<p>Applications Diphenylacetylene is a reagent used in the preparation of polysubstituded pyrroles via oxidative nitrene transfer. Also used in the aerobic coupling of salicyaldehydes with alkynes.<br>References Dewan, A. et al.: ACS Omega, 3, 5327 (2018); Yamane, S. et al.: Chem. A Eur. J., 24, 7852 (2018);<br></p>

<p>Applications 1-(2-Pyridyl)piperazine is a compound that belongs to a class of selective α2-adrenoceptor antagonists. 1-(2-Pyridyl)piperazine shows sympatholytic activity. 1-(2-Pyridyl)piperazine is also a metabolite of Azaperone (A802200).<br>References Saari, W.S. et al.: J. Med. Chem., 26, 1696 (1983); Caccia, S. et al.: J. Chrom., 283, 211 (1984);<br></p>

<p>Applications Benzamide, 2,2'-dithiobis[N-methyl- (cas# 2527-58-4) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Stability Moisture Sensitive<br>Applications Ethyl Malonyl Chloride is used as a reagent in the synthesis of novel thiadiazoloacrylamide analogs as inhibitors of dengue-2 virus NS2B/NS3 protease. Ethyl Malonyl Chloride is also used as a reagent in the synthesis of quinolone-benzylpiperidine derivatives as acetylcholinesterase inhibitors and antioxidant hybrids for Alzheimer disease.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Liu, H., et al.: Bioorg. Med. Chem., 22, 6344 (2014); Pudlo, M., et al.: Bioorg. Med. Chem., 22, 2496 (2014)<br></p>

<p>Applications N1,N4-Di-p-tolylbenzene-1,4-diamine is a useful intermediate for the preparation of some chemically active substances for polymeric materials.<br>References Belorossova, A. G., et al.: Uchenye Zapiski Yaroslavskogo Tekhnologicheskogo Instituta, 11, 200 (1969)<br></p>

<p>Applications Arecoline has shown regulatory properties of controlling plasminogen activator inhibitor-1 expression in human buccal mucosa fibroblasts.<br>References Tsai, C.H., et al.: J. Oral. Pathol. Med., 44, 669 (2015);<br></p>

<p>Applications Formamidine Sulfuric Acid is a reagent used in reduction and synthesis reactions.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ma, Q. et al.: Carbon, 54, 36 (2013);<br></p>

<p>Applications Oxolamine Citrate, is a antiinflammatory drug used as a cough suppressant.<br>References Zhu, X.. et al.: Biopharma. Drug. Disp., 28, 125 (2007); Yuen, T., et al.: Biochem. Biophy. Res. Comm., 422, 573 (2012);<br></p>

<p>Applications 4-Pyridylhydrazine Hcl (cas# 52834-40-9) is a useful research chemical.<br></p>

<p>Impurity Imatinib EP Impurity I<br>Stability Hygroscopic<br>Applications Dimethylamine hydrochloride (Imatinib EP Impurity I) is a precursor to several industrially significant compounds. It is a COVID19-related research product.<br>References Burton, P., et al.: Biochem. J., 432, 575 (2010); Shim, K.S., et al.: DNA Repair., 5, 718 (2006); Robacker, D.C., et al.: J. Chem. Ecol., 23, 1263 (1997);<br></p>

<p>Impurity Anastrozole Monoacid Impurity<br>Applications Anastrozole Mono Acid is an impurity of Anastrozole (A637435), an aromatase enzyme inhibitor and antineoplastic agent. Anastrozole Monoacid Impurity<br>References Plourde, P.V., et al.: Breast Cancer Res. Treat., 30, 103 (1994), Buzdar, A.U., et al.: Cancer, 79, 730 (1997)<br></p>