Building Blocks

<p>Applications (1R,5S,6R)-Ethyl 5-(Pentan-3-yloxy)-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylate is the enantiomer of Ethyl (3R,4S,5S)-4,5-Epoxy-3-(1-ethylpropoxy)cyclohex-1-ene-1-carboxylate (E917820), an intermediate of Oseltamivir.<br>References Clark, C., et al.: J. Med. Chem., 31, 831 (1988)<br></p>

<p>Stability Hygroscopic<br>Applications 2,6-Difluoroaniline is an important chemical in the sythesis technology for high-efficiency insecticide.<br>References Xiong, G.-I. et al.: ANh. Nong. Kex., 36, 9848 (2008);<br></p>

<p>Applications 1-Phenyl-1,2,3,4-tetrahydroisoquinoline is a Solifenacin (S676700) intermediate. 1-Phenyl-1,2,3,4-tetrahydroisoquinoline had been detected in parkinsonian human brain. 1-Phenyl-1,2,3,4-tetrahydroisoquinoline maybe a candidate for endogenous MPTP-like neurotoxin since it is a structural analogue of MPTP which produces parkinsonism in humans.<br>References Kajita, M. et al.: J. Chrom. B Biomed. Appl., 669, 345 (1995);<br></p>

<p>Applications N,N-Dimethylthioformamide<br></p>

<p>Applications Diglycolic Acid is a known metabolite of Diethylene Glycol(D444285) and acts as a nephrotoxic agent in human proximal renal tubule cells. It is also used in the synthesis of N-interlinked imipramines which show apoptotic activity against malignant cells as well as signs of combatting Burkitt’s lymphoma.<br>References Landry, G. et al.: Toxicol. Sci., 124, 35 (2011); Besenhofer, L. et al.: Toxicol. Sci., 123, 374 (2011); Bright, S. et al.: Bioorg. Med. Chem. Lett., 23, 1220 (2013);<br></p>

<p>Applications Cyclooctatetraene is used as a reactant in the synthesis of tricyclo[4.2.2.02,5]dec-9-ene-3,4,7,8-tetracarboxylic acid diimide, an antitumor drug.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Vishnuvajjala, B.R., Cradock, J.C.: J. Pharm. Sci., 75, 301 (1986)<br></p>

<p>Applications DL-Lactide (cas# 95-96-5) is a useful research chemical.<br></p>

<p>Applications Polyoxyl 35 Castor Oil is a triglyceride fatty acid which has the potential to repel insects and promote plant growth.<br></p>

<p>Applications 6,7-Dimethoxyisoquinoline is used as an organocatalyst in the chemoselective O-tert-butoxycarbonylation of phenols.<br>References Saito, Yukako, et al.: Tetrahedron Let., 51(52), 6915-6917 (2010)<br></p>

<p>Applications Ethylenediamine Dihydrochloride (cas# 333-18-6) is a useful research chemical.<br></p>

<p>Applications 2-METHYL-3-PHENYLPROPIONALDEHYDE (cas# 5445-77-2) is a useful research chemical.<br></p>

<p>Applications Cyclopropanecarboxylic Acid is used as a reagent in the synthesis of substituted 4-(thiophen-2-ylmethyl)-2H-phthalazin-1-ones as potent PARP-1 inhibitors. Also used as a reagent in the synthesis of 2-alkyloxazoles as potent and selective PI4KIIIβ inhibitors demonstrating inhibition of HCV replication.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Wang, L., et al.: Bioorg. Med. Chem. Lett., 24, 3739 (2014); Keaney, E.P., et al.: Bioorg. Med. Chem. Lett., 24, 3714 (2014)<br></p>

<p>Applications Cyclopentanone-2,2,5,5-d4 (CAS# 3997-89-5) is a useful isotopically labeled research compound.<br></p>

<p>Applications Menthyl Acetate is a component of essential oils extracted from natural sources.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Adaszynska, Michalina, et al.: Zywnosc, 20(2), 116-125 (2013);Hashimoto, Gabriela S., et al.: Aquaculture, 450, 182-186 (2016);Mazzucotelli, Maria, et al.: J. of Chrom. A, 1583, 124-135 (2019)<br></p>

<p>Applications Methyl 2-bromo-2-methylpropanoate (cas# 23426-63-3) is a useful research chemical.<br></p>

<p>Stability Air Sensitive, Hygroscopic<br>Applications 2-Ethylhexyl-4-aminobenzoate is an impurity in the synthesis of Ethylhexyl Triazone (E918810), used in sunscreen formulations as a UV filter to block out harmful ultraviolet light.<br>References Potard, G. et al.: Int. J. Pharm., 189, 249 (1999); Couteau, C. et al.: J. Pharm. Biomed. Anal., 44, 270 (2007);<br></p>

<p>Stability Light Sensitive<br>Applications Iodoacetonitrile (cas# 624-75-9) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>