Building Blocks

<p>Applications An intermediate for the synthesis of Norharmane.<br>References Peifer, C., et al.: J. Med. Chem., 50, 1213 (2007),<br></p>

<p>Applications 5-Phenyl-1H-1,2,3-triazole (cas# 1680-44-0) is a useful research chemical.<br></p>

<p>Applications Phosphorus(V) Oxybromide is a reagent used in the preparation of phosphoryl halide for N-protection of amino acids using group assisted purification (GAP). Phosphorus(V) Oxybromide is a brominating agent.<br>References An, G., et al.: Heterocycles, 90, 344 (2015); Guo, J., et al.: Hebei Gongye Daxue Xuebao, 40, 57 (2011); Golding, D., et al.: J. Org. Chem., 12, 293 (1947)<br></p>

<p>Stability Moisture Sensitive<br>Applications Eye irritant.<br>References Bagley, D. M. et al.; Toxicol. In Vitro 13, 505 (1999); Gilleron, L. et al.; Toxicol. In Vitro 11, 641 (1997)<br></p>

<p>Stability Light Sensitive<br>Applications 3-Phenyl-5-vinyl-1,2,4-oxadiazole is a chemical reagent used in the synthesis of pharmaceutically active motifs.<br>References Burns, A. et al.: Org. Biomol. Chem., 8, 2777 (2010); Catanese, B. et al.: Exp. Mol. Path. Supp., 2, 28 (1963);<br></p>

<p>Applications Azodicarbonyl reagent used in the methods for determining levels of 1,25 dihydroxyvitamin d2 and d3 in biological and food samples and dietary supplements.<br>References Aranov, P. K. et al.: Anal. Bioanal. Chem., 391, 1917 ( 2008),<br></p>

<p>Impurity Solifenacin EP impurity A<br>Applications Solifenacin (S676700) intermediate.<br>References Andersson, K., et al.: Drugs, 35, 477 (1988), Wallis, R., et al.: Life Sci., 64, 395 (1999), Mitsuya, M., et al.: J. Med. Chem., 43, 5017 (2000), Ohtake, A., et al.: Eur. J. Pharmacol., 492, 243 (2004),<br></p>

<p>Applications 1-Phenyl-1,2,3,4-tetrahydroisoquinoline is a Solifenacin (S676700) intermediate. 1-Phenyl-1,2,3,4-tetrahydroisoquinoline had been detected in parkinsonian human brain. 1-Phenyl-1,2,3,4-tetrahydroisoquinoline maybe a candidate for endogenous MPTP-like neurotoxin since it is a structural analogue of MPTP which produces parkinsonism in humans.<br>References Kajita, M. et al.: J. Chrom. B Biomed. Appl., 669, 345 (1995);<br></p>

<p>Applications Phenylboronic Acid is a compound used in organic synthesis of various pharmaceutical goods.<br>References Ainley, A.D., et al.: J. Chem. Soc., 2171 (1930);<br></p>

<p>Applications (E)-1-Phenyl-1-butene was used to study olefin oxidation by cytochrome P-450. It can be used to synthesize nonracemic allylic amines. It can also be used to prepare aryl oxiranes by direct epoxidation.<br>References Liebler, D., et al.: Biochem., 22, 5482 (1983); Liang, C., et al.: J. Am. Chem. Soc., 130, 343 (2008); Imuta, M., et al.: J. Org. Chem., 44, 1351 (1979)<br></p>

<p>Impurity Aspartame EP Impurity C<br>Applications L-Phenylalanine (Aspartame EP Impurity C) is an essential amino acid. L-Phenylalanine is biologically converted into L-tyrosine, another one of the DNA-encoded amino acids, which in turn is converted to L-DOPA and further converted into dopamine, norepinephrine, and epinephrine. L-Phenylalanine is produced for medical, feed, and nutritional applications such as in the preparation of Aspartame. Neuroprotective product.<br>References Hollunger, G. et al.: Acta Pharmacol. Toxicol., 34, 391 (1974); Bagchi, S.P. et al.: Biochem. Pharmacol., 26, 900 (1977);<br></p>

<p>Applications D-Phenylalanine, the stereoisomer of L-Phenylalanine (P319415) has been used in the synthesis of Schaeffer’s acid analogues as important structures in tuberculostatic design. They exhibit the ability to inhibit Mycobacterium tuberculosis type II dehydroquinase.<br>References Schmidt, M. et al.: ChemMedChem., 8, 54 (2013);<br></p>

<p>Applications pyrrolo[1,2-a]pyrazine-1-carboxylic acid (cas# 1895300-97-6) is a useful research chemical.<br></p>

<p>Applications 1,2,2,6,6-Pentamethylpiperidine is used in the synthesis of BN-fused polycyclic aromatic molecules for potential application to electronic materials and apparatus. In addition, it is a catalyst for the chemoselective silylation of benzylic alcohols.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Hatakeyama, T. J. Am. Chem. Soc., 133, 18614 (2011); Naiki, M. et al.: Tetrahedron Lett., 42, 5467 (2001);<br></p>

<p>Stability Moisture Sensitive<br>Applications Pentafluorobenzoyl Chloride is a useful analytical reagent in the derivatization amphetamines as well as other primary amines.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Koster, E. et al.: Analyst, 127, 598 (2002);<br></p>

<p>Applications Hexadecanoic-9,9,10,10,11,11,12,12,13,13,14,14,15,15,16,16,16-d17 Acid (CAS# 81462-28-4) is a useful isotopically labeled research compound.<br></p>