Building Blocks

<p>Applications trans-Indole-3-acrylic Acid is a regent used as a matrix for MALDI-TOF mass spectroscopy in order to characterize polyphenols.<br>References Madrigal-Carballo, S., et al.: Int Food Res J, 20, 2023-2034 (2013)<br></p>

<p>Applications Indole-3-acetamide is a compound that is converted to indole-3-acetic acid by indole-3-acetamide hydrolase in auxin biosynthesis in plants.<br>References Mano, Y., et al.: J. Exp. Bot., 61, 25 (2010)<br></p>

<p>Applications 10-Hydroxybenzo[h]quinoline-7-sulfonate is used as a fluorescence method for the determination of beryllium and beryllium oxide particles.<br>References Agrawal, A., et. al.: J. ASTM Int., 8, 10 (2011); Zheng, Y., et. al.: Talanta, 85, 638 (2011)<br></p>

<p>Stability Unstable in solution<br>Applications Inhibits cancinogenesis at the initiation stage. A metabolite of 3-methylindole<br>References Stresser, D.M., et al.: J. Biochem. Toxicol., 10, 191 (1995), Bailey, G.S., et al.: J. Natl. Cancer Inst., 78, 931 (1987), D’Agostino et. al. Drug Metabolism and Disp. 27: 2018 (2009)<br></p>

<p>Applications 2-Chloro-1,3-benzothiazole is used in the synthesis of CBTs which are good building blocks for bioluminescent compounds for imaging.<br>References Hauser, J. et al.: Bell. J. Org. Chem., 12, 2019 (2016);<br></p>

<p>Applications 4-Thiouracil is a derivative of Uracil (U801000), which is a nitrogenous base in RNA nucleic acid. 4-Thiouracil is used for tagging in cell type-specific RNA isolation from intact complex tissues.<br>References Miller, M., et al.: Nat. Methods, 6, 439 (2009); Seth, P., et al.: J. Med. Chem., 53, 8309 (2010); Cui, H., et al.: Eur. J. Med. Chem., 45, 5140 (2010);<br></p>

<p>Applications 3,6-Dichloro-2-hydroxybenzoic Acid Potassium Salt, is a hydroxybenzoic acid derivative and can be synthesized using a Kolbe-Schmitt carboxylation and acidification reaction of 2,5-dichlorophenol.<br>References Zhao, W-H., Song, G-Z.: Huagong Jishu Yu Kaifa, 44, 39-41 (2015)<br></p>

<p>Applications 2-Bromo-2-phenylacetic acid<br></p>

<p>Applications 2-Fluoropropionic acid is used in the medical field for diagnostic purposes. It is labelled with 18F and is used as an imaging agent for detecting prostate cancer in humans. 2-Fluoropropionic acid is also used to prepare 2-fluoro fatty acids, compounds that exhibit antifungal properties.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Gershon, H. &amp; Parmegiani, R.: J. Med. Chem., 10, 186 (1967); Pillarsetty, N., et al.: J. Nucl. Med., 50, 1709 (2009);<br></p>

<p>Applications 3-chloro-1-(4-methylphenyl)propan-1-one is a reagent used in the synthesis of Mannich base-type derivatives which can be used in the treatment of chagas disease.<br>References Martin-Escolano, R. et al.: J. Med. Chem., 61, 5843 (2018);<br></p>

<p>Applications Indole-2-carboxylic Acid (cas# 1477-50-5) is a compound useful in organic synthesis.<br></p>

<p>Applications 4-Bromo-6-methyl-3H-1,3-benzodiazole<br></p>

<p>Applications Ferulic Acid Methyl Ester is a derivative of Ferulic Acid (F308900), used as an antioxidant and food preservative. It has less antioxidant capacity than ferulic acid.<br>References Smart, M.G., et al.: Aust. J. Plant Physiol., 6, 485 (1979), Chen, C., et al.: J. Food Lipids, 2, 35,1995, Benzie, I., et al.: Anal. Biochem. 239, 70 (1996), Nardini, M., et al.: Food Chem., 79, 119 (2002), Lee, J., et al.: J. Agric. Food Chem., 52, 2647 (2004),<br></p>

<p>Applications O-2-Propynylhydroxylamine hydrochloride (cas# 21663-79-6) is a useful research chemical.<br></p>

<p>Stability Hygroscopic<br>Applications Genetic incorporation of a metal-ion chelating amino acid into proteins as a biophysical probe.<br>References McRee, D., et al.: J. Struct. Biol., 125, 156 (1999), Wang, L., et al.: Science, 292, 498 (2001), Ioerger, T., et al.: Methods Enzymol., 374, 244 (2003),<br></p>