Building Blocks

<p>Stability Unstable in acidic solution<br>Applications Trimethyl Orthovalerate is used in the synthesis of dihydropyran-4-ones, via the Maitland-Japp reaction, which can be converted stereoselectively into tetrahydropyran-4-ones. This conversion is useful in the study of the functionalized tetrahydropyran units that are found in the anticancer polyketide lasonolide A and the Civet fragrance which is used in perfumery.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Clarke, P., et al.: Org. Biomol. Chem., 13, 4743 (2015)<br></p>

<p>Applications N-Benzoyl Isothiocyanate (cas# 532-55-8) is a compound useful in organic synthesis.<br></p>

<p>Applications 4-Methylenepiperidine Hydrochloride is a building block that can be coupled with aryl halides via Suzuki cross-coupling to give benzyl piperidines and related compounds.<br>References Vice, S., et al.: J. Org. Chem., 66, 2487 (2001);<br></p>

<p>Applications 1-Iodoheptafluoropropane chain transfer agent; used in preparation method of binary Peroxyfluoro rubber and smart wearable material.<br>References Zhou, W., et al.: Faming Zhuanli Shenqing, (2020);<br></p>

<p>Stability Hygroscopic<br>Applications Trimethyl Orthobenzoate is a reagent used in the synthesis of quinazolines. Also used in the prepaaration of nintedanib (N478290), used in the treatment of idiopathic pulmonary fibrosis. Also inhibits the process blood vessel formation which may be used to assist in cancer therapy.<br>References Bhat, S. et al.: J. Hetero. Chem., 52, 1253 (2015); Xu, R. et al.: J. Labelled. Comp. Radiopharm., 58, 308 (2015);<br></p>

<p>Applications Benzyl Glycolate was utilized as a potential moiety for the preparation of phosphonate dipeptides as potential inhibitors of VanX.<br>References Jia, C., et al.: BIoorg. Med. Chem. Lett., 22, 482 (2012);<br></p>

<p>Applications Lasofoxifene intermediate.<br>References Tatee, T., et al.: J. Med. Chem., 22, 1509 (1979), Wellmann, F., et al.: J. Biosci., 46, 252 (1991),<br></p>

<p>Applications A reagent used for the synthesis of hydroxylamines and hydroxyamates.<br>References Magin, D.F., et al.: J. Chromatogr., 178, 219 (1979), Safavy, A., et al.: Bioconjug. Chem., 13, 327 (2002),<br></p>

<p>Applications cis-1,3-O-Benzylideneglycerol (cas# 4141-19-9) is a compound useful in organic synthesis.<br></p>

<p>Stability Hygroscopic<br>Applications N,N,N'-Trimethyl-1,3-propanediamine is a reactant that as a ligand, racemizes aromatic alcohols completely in the prescence of a ruthenium-based racemization catalyst.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Riermeier, T.H., et. al.: Tetrahedron Lett., 46, 3403 (2005)<br></p>

<p>Applications Bicyclo[2.2.1]hept-2-ene is a catalyst used in many reactions such as in the cascade cyclizations of iodoarene, bromobenzylamine, and electron-deficient alkene derivatives and arene C-H amination with aryl halides.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Narbonne, V., et. al.: Org. Lett., 16, 628 (2014); Dong, Z., Dong, G.: J. Am. Chem. Soc., 135, 18350 (2013)<br></p>

<p>Applications H-PRO-GLU-OH (cas# 67644-00-2) is a useful research chemical.<br></p>

<p>Applications meso-Tetra (N-methyl-2-pyridyl) porphine tetrachloride is a synthetic porphyrin for research.<br></p>

<p>Applications Ethyl 3-bromopropionate<br></p>

<p>Applications 6-Mercapto-1-hexanolcan be used as a chemical linker for anchoring biological molecules to gold surfaces.<br>References McKinlay, C. J. et al.: J. Am. Chem. Soc 138, 3510 (2016)<br></p>