Building Blocks

<p>Applications Used for synthesis of Rho kinase inhibitors.<br>References Biggadike, K., et al.: J. Med. Chem., 50, 6519 (2007), Cheng, Y., et al.: Bioorg. Med. Chem., 16, 4617 (2008),<br></p>

<p>Applications This compound has been shown to inhibit iodothyronine 5’-deiodinase, the enzyme responsible for the 5’-deiodination of thyroxine in human liver cells.<br>References Harbottle, R., et al.: Biochem. J., 217, 485 (1984),<br></p>

<p>Applications 2-​Amino-​6-​methylpyridine is a reagent used in the identification of selective inhibitor for phosphatidylinositol 3-kinase (PI3Kα).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Miller, M. S., et al.: Bioorg. Med. Chem., 25, 1481-1486 (2017);<br></p>

<p>Stability Air Sensitive, Stench<br>Applications Allyl Mercaptan (&gt;75%) can be used to treat Alzheimer's, stroke, cardiovascular and other amyloid related diseases.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Postrel, R., U.S. Pat. Appl. Publ. US 20200215009 A1, 10, (2020);<br></p>

<p>Stability Hygroscopic<br>Applications Aminomalononitrile p-toluenesulfonate is a reagent for diazonamide synthesis via heck endocyclization. It may also have implications for developing IκB Kinase-β inhibitors.<br>References Jeong, S., et al.: J. Org. Chem 63, 8640 (1998); Morwick, T. et al.: J. Med. Chem. 49, 2898<br></p>

<p>Applications Ammonium sulfide is a very useful reagent in various aspects ranging from large scale production of textile manufacture, trace metal analysis, patina to bronze, and as well as cell culture and organic reactions/synthesis. Recently it has been used as a cleaning solution in the study of semiconductor growth on indium phosphide with various metals.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ferrandis, P., et al.: J. Appl. Phys., 123, 161534/1-161534/10 (2018)<br></p>

<p>Applications 1,3-Benzothiazole-4-sulfonyl Chloride (cas# 149575-65-5) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications Betahistine free base (cas# 5638-76-6) is a useful research chemical.<br></p>

<p>Applications 4-methyl-3-oxoheptanenitrile (cas# 1039833-22-1) is a useful research chemical.<br></p>

<p>Applications Used in the preparation of phenyloxadiazolyl pyridines as immunomodulating agents.<br>References Iwakubo, M., et al.: Bioorg. Med. Chem., 15, 350 (2007), Schaafsma, D., et al.: Eur. J. Pharmacol., 585, 398 (2008),<br></p>

<p>Applications Used for preparation of [[(triazolylmethyl)pyridyl]phenyl]tetrazoles and related compounds as cardiovascular agents.<br>References Behforouz, M., et al.: J. Med. Chem., 46, 5773 (2003), Behforouz, M., et al.: Bioorg. Med. Chem., 15, 495 (2007),<br></p>

<p>Applications An intermediate of pyridinyl pyrrole compounds as proton pump inhibitors with improved gastric acid secretion suppressive activity.<br>References Tomasi, J., et al.: Chem. Rev., 105, 2999 (2005), Godula, K., et al.: Science, 312, 67 (2006), Davies, H., et al.: Nature, 451, 417 (2008),<br></p>

<p>Applications 4-Bromophenylacetic Acid (cas# 1878-68-8) is a compound useful in organic synthesis.<br></p>

<p>Applications 1-​Bromododecane (n-Lauryl Bromide) is a reagent used in the synthesis of porous organic polymers.<br>References Zhao, Y. et al.: ACS Macro. Lett., 7, 300 (2018);<br></p>

<p>Applications A useful synthetic intermediate. It is used as a reactant in synthetic preparation of chiral 2-carboxy cyclic ethers.<br>References Zhu, S., et al.: J. Am. Chem. Soc., 132, 16374 (2010);<br></p>

<p>Applications 2-Bromothiazole is a heterocyclic S compound to induce base-pair substitution and having mutagenic activity.<br>References Voogd, C.E., et al.: Mutation Research, Genetic Toxicology Testing, 118, 153 (1983),<br></p>

<p>Applications 1-Bromo-4-phenylbutane<br></p>

<p>Applications 2-Butynoic Acid is used as a reagent in the synthesis of BMS 911543 (B596075); a potent JAK2 inhibitor used as a potential treatment for myeloproliferative disorders. 2-Butynoic Acid is also used in the preparation of chirally pure 1,2,3,4-tetrahydroisoquinoline analogs as anti-cancer agents.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Fitzgerald, M.A., et al.: J. Org. Chem., 80, 6001 (2015); Ramanivas, T., et al.: Eur. J. Med. Chem., 92, 608 (2015)<br></p>

<p>Applications Butyric Anhydride is a chemical reagent used in the synthesis of amidoamine dendron-based co-adsorbents used in the improvement of dye-sensitized solar cells. Also used in the synthesis of allopurinol derivatives for their activity against Trypanosoma cruzi.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Xu, J. et al.: J. Mat. Chem. Mat. Energy Sust., 1, 14524 (2013); Raviolo, M. et al.: 69, 455 (2013);<br></p>