Building Blocks

<p>Applications Forest fires are actually beneficial for ecosystems, provided they don’t happen too often. After a fire, plants germinate and grow incredibly fast. 2H-Furo[2,3-c]pyran-2-one, KAR2, is a compound in smoke responsible for promoting the seed germination of a wide range of plant species. The researchers named the compounds “the karrikins”, for “karrik”, an aboriginal word for smoke.<br>References Sakuma, H., et al.: .Agric Biol. Chem., 45, 443 (1981), Stevens, J., et al.: Plant Soil, 298, 113 (2007), Nelson, D., et al.: Plant Physiol., 149, 863 (2009),<br></p>

<p>Applications (1R,2R)-2-(3,4-Difluorophenyl)cyclopropanecarboxamide is a part of the synthetic preparation of the synthesis and inhibitory effect on ADP-induced platelet aggregation of ticagrelor derivatives as antiplatelets agents.<br>References Zhang, H., et al.: Bioorganic Med. Chem. Lett., 22, 3598 (2012).<br></p>

<p>Applications 2,5,6,7-tetrahydro-1H-azepin-2-one (cas# 2228-79-7) is a useful research chemical.<br></p>

<p>Applications 2,5-Diformylfuran (cas# 823-82-5) is a compound useful in organic synthesis.<br></p>

<p>Applications Diethyl Sulfone is a reagent used in the synthesis of heterocyclic compounds including of β-ketosulfones. Also used in the preparation of sulfone-based electrolytes for aluminum electrodeposition.<br>References Legrand, L.. et al.: Electrochem. Act., 40, 1711 (1995); Katritzky, A. et al.: J. Org. Chem., 68, 1443 (2003);<br></p>

<p>Applications N1,N4-Di-p-tolylbenzene-1,4-diamine is a useful intermediate for the preparation of some chemically active substances for polymeric materials.<br>References Belorossova, A. G., et al.: Uchenye Zapiski Yaroslavskogo Tekhnologicheskogo Instituta, 11, 200 (1969)<br></p>

<p>Applications Labeled D-Ribitol, which is used in the preparation of L-ribose and and arabinose. it is also a diagnostic tool for identifying human bladder cancer (HBC) through noninvasive urinary metabonomics.<br>References Pasikanti, K. et al.: J . Proteo. Res., 9, 2988 (2010); Ahmed, Z. et al.: J. Biosci. Bioeng., 88, 444 (1999);<br></p>

<p>Stability Hygroscopic<br>Applications Genetic incorporation of a metal-ion chelating amino acid into proteins as a biophysical probe.<br>References McRee, D., et al.: J. Struct. Biol., 125, 156 (1999), Wang, L., et al.: Science, 292, 498 (2001), Ioerger, T., et al.: Methods Enzymol., 374, 244 (2003),<br></p>

<p>Stability Light Sensitive<br>Applications MPEP is a potent and highly selective non-competitive mGlu5a receptor antagonist (1,2). It is also a positive allosteric modulator at mGlu4 receptors.MPEP exhibits anxiolytic and antidepressant properties that may be applicable for treating schizophrenia (3).<br>References (1) Latif-Hemandez, A., et al.: Front Cell Neurosci. 10, 252 (2016)(2) Hikichi, H. et al.: Eur. J. Pharmacol., 639, 99 (2010)(3) Inta, I., et al.: Pharmacopsychiatry. 49, 142 (2016)<br></p>

<p>Applications (S)-2-((S)-2-Amino-4-methylpentanamido)-4-methylpentanoic acid (cas# 3303-31-9) is a useful research chemical.<br></p>

<p>Applications 4-(2-Chloroethyl)morpholine is used in the preparation of potential DNA cross-linking antitumor agents as well as synthetic opiate analogues. 4-(2-Chloroethyl)morpholine may possess sickle-cell hemoglobin aggregation inhibiting-activity.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Anderson, F.M. et al.: Anti-Cancer Drug Des., 15, 119 (2000); Stubbins, J.F. et al.: Eur. J. med. Chem., 14, 219 (1979);<br></p>

<p>Applications 3-Methyluridine can be used in biological and analytical studies of comprehensive profiling of ribonucleosides modification by affinity zirconium oxide-​silica composite monolithic column online solid-​phase microextraction - mass spectrometry analysis.<br>References Jiang, H., et al.: J Chromatogr A, 1462, 90 (2016)<br></p>

<p>Applications α-Chloroethyl Chloroformate (cas# 50893-53-3) is a compound useful in organic synthesis.<br></p>

<p>Applications 2-Amino-4-(trifluoromethyl)benzenethiol Hydrochloride can be used as reactant/reagent in preparation of fused benzo-diazepinones/oxazocinone/thiazapines/diazapines/diazocins/thiazine/indoles via CuI-L-proline catalyzed SN2 reaction.<br>References Srinivasulu, V., et al.: Tetrahedron, 73, 2139 (2017)<br></p>

<p>Impurity Levothyroxine EP Impurity C; T3-Acetic Acid (USP)<br>Applications 3,3',5-Triiodo Thyroacetic Acid (T3-Acetic Acid (USP)) is a thyroid hormone analogue. A potent Thyroxine impurity. Levothyroxine EP Impurity C.<br>References Horst, C., et al.: Biochem. J., 261, 945 (1989), Kvetny, J., et al.: Horm. Metab. Res., 24, 322 (1992), Yamauchi, K., et al.: J. Biol. Chem., 274, 8460 (1999), Davis, P., et al.: J. Endocrinol. Invest., 25, 377 (2002),<br></p>