Building Blocks

<p>Applications 1,6-Diphenyl-1,3,5-hexatriene is an alternative to Nile red for fluorescent detection of lipid droplets.<br></p>

<p>Applications tert-butyl 2-oxo-7-azaspiro[3.5]nonane-7-carboxylate (cas# 203661-69-2) is a useful research chemical.<br></p>

<p>Stability Light Sensitive<br>Applications N,N'-Di(1,3,4-thiadiazol-2-yl)methanediamine inhibits DNA and RNA syntheses by mouse embryo cells.<br>References Tsukamoto, K., et. al.: Cancer Res., 35, 2631 (1975)<br></p>

<p>Applications 1,4-Dithiane has been studied to be used as a way for more efficient rechargeable iron-​air and nickel-​iron batteries through small addition of organo-sulur compounds to metal electrodes.<br>References Yang, B., et al.: Energy Environ. Sci., 7, 2753-63 (2014);<br></p>

<p>Applications 2-(1,3,5-Dithiazinan-5-yl)ethanol is an amorphous dithiazine formed during the removal of hydrogen sulfide from hydrocarbon steams using triazine scavenger.<br>References Taylor, G, N., et al.: Indust. Engin. Chem. Res., 51, 11613 (2012); Taylor, G.N., et al.: Indust. Engin. Chem. Res., 50, 735 (2011);<br></p>

<p>Applications 5,5-Dimethyl-1,3-dioxane is used in preparation of Neopentyl Glycol.<br>References Cao, S., et al.: Faming Zhuanli Shenqing, (2013);<br></p>

<p>Trans-4-coumaric acid or p-coumaric acid, is a derivative of the cinnamic acid. It is the initial substrate to produce several intermediates such as ferulic acid, caffeic acid, rosmarinic acid, gallic acid, and carnosic acid. Trans-4-coumaric acid, as well as its derivatives, have antioxidant properties; they are common ingredients in cosmetics and as dietary supplement.</p>

<p>3-{[(Benzylsulfanyl)methanethioyl]sulfanyl}propanoic acid are essential mediators for reversible addition-fragmentation chain transfer (RAFT) polymerization, common type of controlled radical polymerization.</p>

<p>Versatile small molecule scaffold</p>

<p>1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-3-hydroxypiperidine-2-carboxylic acid is a reaction component that can be used in the synthesis of a variety of chemical compounds. This product has been shown to be useful as a scaffold for the synthesis of complex compounds, and as an intermediate for the synthesis of speciality chemicals. It has also been found to have versatile building block properties and is used in the production of fine chemicals.</p>

<p>2-(Nitromethylidene)-1,3-thiazinane is a chemical compound that has been shown to have chronic toxic effects in animal studies. It binds to the ryanodine receptor and inhibits the release of calcium from the sarcoplasmic reticulum, which may lead to an increase in acetylcholine, a neurotransmitter involved in many aspects of brain function. 2-(Nitromethylidene)-1,3-thiazinane has also been shown to inhibit the activity of neonicotinoids, insecticides that are used for agricultural and veterinary purposes. This compound is structurally similar to other non-competitive inhibitors of acetylcholine esterase, such as piperonyl butoxide.</p>

<p>2-Azaspiro[3.5]nonane hydrochloride is a high quality reagent that is used as an intermediate for the synthesis of complex organic compounds, such as fine chemicals and speciality chemicals. It has been shown to be useful in the synthesis of a variety of chemical compounds, including research chemicals and versatile building blocks. This compound has the CAS number 1303968-07-1.</p>

<p>Thieno[3,2-c]pyridine-7-carboxylic acid is an anticancer drug that belongs to the class of acid derivatives. It has been shown to be active against solid tumors and has been found to be effective in inhibiting tumor growth and proliferation. Thieno[3,2-c]pyridine-7-carboxylic acid is a prodrug that is activated by hydrolysis of the ester group. The activation process occurs through an enzymatic mechanism that requires two enzymes: carboxylesterase and cytochrome P450.</p>

<p>PF-04965842 is an anti-inflammatory drug that belongs to the class of Jak1 inhibitors. It is used in the treatment of alopecia areata, dermatitis, and bowel disease. PF-04965842 is a selective inhibitor of JAK3 and blocks signaling through this pathway. PF-04965842 has been shown to have long-term efficacy in the treatment of inflammatory skin diseases such as atopic dermatitis and psoriasis. In addition, it has been demonstrated to be effective in reducing symptoms associated with inflammatory bowel disease (IBD) and ulcerative colitis. PF-04965842 also inhibits the production of proinflammatory cytokines by inhibiting the activation of inflammatory cells in the skin or gut.</p>

<p>Versatile small molecule scaffold</p>

<p>Heterocycle with nitrile functional handle</p>

<p>Versatile small molecule scaffold</p>