Building Blocks

Applications An α-keto ester derivative.

Applications Bis(2-chloroethyl)-d8-amine HCl (CAS# 102092-04-6) is a useful isotopically labeled research compound.

Stability Hygroscopic
Applications L-Proline Methyl Ester Hydrochloride (cas# 2133-40-6) is a compound useful in organic synthesis.

Applications p-Toluidine Hydrochloride acts as a reagent for the preparation and biological activity of N-acylleucine (arylaminoethyl)amides as non-covalent inhibitors of cathepsin K, L and S. Catalyst in the chemistry of azasteroids.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Altmann, E., et al.: J. Med. Chem., 45, 2352 (2002); Vedres, A., et al.: Acta Chimica Academiae Scientiarum Hungaricae, 109, 111 91982)

Applications 2,2’-Iminobis(N-(2,6-Dimethylphenyl)acetiamide is an impurity in the synthesis of Lidocaine Hydrochloride (L397800), an anesthetic local agent and antiarrythmic class IB agent.
References Duce, R., et al.: J. Pharmacol. Exp. Ther., 179, 580 (1971), Kronberg, G.H., et al.: J. Med. Chem., 16, 739 (1973), Groningsson, K., et al.: Anal. Profiles Drug Subs., 14, 207 (1985), Davies, P.S., et al.: Drugs, 64, 937 (2004),

Applications A Sulfamethoxazole metabolite.
References Gill, H., et al.: Br. J. Clin. Pharmacol., 42, 347 (1996), Winter, H., et al.: Clin. Pharmacol. Ther., 76, 579 (2004), Vyas, P., et al.: Biochem. Pharmacol., 70, 275 (2005), Vyas, P., et al.: Drug Metab. Dispos., 34, 16 (2006),

Stability Moisture Sensitive
Applications Pentafluorobenzoyl Chloride is a useful analytical reagent in the derivatization amphetamines as well as other primary amines.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Koster, E. et al.: Analyst, 127, 598 (2002);

Applications Used in the synthesis of selective β-adrenergic blocker Metoprolol.
References Su, W., et al.: J. Chem. Res., 6, 414 (2004),

Applications Cyclopropanecarboxylic Acid is used as a reagent in the synthesis of substituted 4-(thiophen-2-ylmethyl)-2H-phthalazin-1-ones as potent PARP-1 inhibitors. Also used as a reagent in the synthesis of 2-alkyloxazoles as potent and selective PI4KIIIβ inhibitors demonstrating inhibition of HCV replication.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Wang, L., et al.: Bioorg. Med. Chem. Lett., 24, 3739 (2014); Keaney, E.P., et al.: Bioorg. Med. Chem. Lett., 24, 3714 (2014)

Applications (±)-3-tert-Butoxy-1,2-propanediol is a diesel fuel additive.
References Frusteri, F., et al.: Appl. Catal., 367, 77 (2009)

Applications N-Nitrosohexamethylenimine is a carcinogen.
References Goodall, C. M., et al.: Toxicology, 33, 251 (1984); Lijinsky, W., et al.: J. Cancer Res. Clin. Oncol., 108, 46 (1984); Goodall, C. M., et al.: JNCI, J. Natl Cancer Inst., 73, 1215 (1984)

Applications Dibenzyl Phosphite is used in the preparation of phenylalkylphosphonamidates which are then used as probes for a hydrophobic binding register in prostate-specific membrane antigen.
References Maung, J. et al.: Bioorg. Med. Chem., 12, 4969 (2004);

Applications 2,3-Diethyl-5-methylpyrazine is a volatile compound found in food such as almonds and swiss cheese.
References Manzano, P. et. al.: J. Sep. Sci., 37, 675 (2014); Taylor, K., et. al.: J. Food Sci., 78, C1509 (2013)

Applications Bis(2-butoxyethyl) 2-Hydroxyethyl Phosphate Triester is a metabolite of Tris(2-butyloxyethyl)phosphate (T875030), which is an organophosphate, that can be used in the preparation of flame retardant, such as viscose fiber.
References Wang, Y., et al.: Fangzhi Xuebao, 33, 16 (2012); Xiaoshan, L. et al.: Aquatic Toxicology, 114, 173 (2012);

Applications Thiamine (T344185) antagonist. Thiamine (T344185) analog.
References Cooper, J., et al.: J. Neurochem., 19, 1809 (1972), Patrini, C., et al.: Brain Res., 628, 179 (1993), Nauti, A., et al.: Metab. Brain Dis., 12, 145 (1997),

Applications DL-Homocysteine is an allosteric antagonist at the dopamine d2 receptors. Mainly, L-Homocysteine (H591950) exists naturally and is recycled into methionine or converted into cysteine.
References Agnati, L. et al.: J. Proteome Res. 5, 3011 (2006); Stipanuk, M. et al.: Ann. Rev. Nutrition., 24, 539 (2004);

Applications Acetylpyrazine (cas# 22047-25-2) is a useful research chemical.