Building Blocks

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>PKC-theta inhibitors are a class of compounds that inhibit protein kinase C-theta (PKC-θ), which is a serine/threonine-specific protein kinase. PKC-θ inhibition is being studied as a potential therapeutic strategy for the treatment of Alzheimer's disease and HIV integrase inhibitor. A number of strategies have been developed to inhibit the enzyme, including paraformaldehyde, nucleophilic substitutions, primary amines, and alkylation. These strategies have yielded different yields and chemotypes with varying bioactivity profiles.</p>

<p>6-(Hydroxymethyl)pyridine-3,4-diol is a ligand that binds to the opioid receptor and is used as a tool for studying opioid receptors. The ligand has been shown to bind specifically to the mu-, delta-, and kappa-opioid receptors in rat brain membranes and is an agonist for these receptor types. 6-(Hydroxymethyl)pyridine-3,4-diol has also been shown to be an antagonist for the nociceptin receptor. This compound has been analyzed using quantum chemistry tools to determine its electronic structure and geometry. The energies of these molecules have been calculated using quantum chemistry calculations. Geometric parameters were optimized by minimizing the energy of the molecule using molecular mechanics calculations. Parameters such as solvation, complex formation, and chelate constants have also been determined with quantum chemistry calculations. The binding constants are then analyzed with quantum chemistry methods to optimize the parameters of structures in order to find those structures with</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

5-(Morpholine-4-sulfonyl)-2-phenoxyaniline is a potent inhibitor of the nicotinic acetylcholine receptor. This drug binds to the alpha subunit of the nicotinic acetylcholine receptor, which allows it to inhibit the ion channel and prevent depolarization of the cell membrane. 5-(Morpholine-4-sulfonyl)-2-phenoxyaniline is a white solid that is soluble in organic solvents. It has been used as a research tool and an inhibitor in pharmacological studies.