Building Blocks

Versatile small molecule scaffold

2-Azido-1,3-difluorobenzene is a photoactive compound that can be used to form an azide. It has been shown to undergo photochemical reactions to form the triplet state and then isomerize to the singlet state. This reaction can be initiated by a laser beam or other light source, such as sunlight. The triplet state of 2-azido-1,3-difluorobenzene has been shown to react with organic molecules containing electron withdrawing groups on their molecules, such as 2-methoxy-2-methylpropane. When these two substances are mixed together, they react to form an isomerized product that has a carbonyl group in its structure. This reaction could be helpful for developing new synthetic methods for producing pharmaceuticals and other compounds with important functions in chemistry and physics.

Versatile small molecule scaffold

Versatile small molecule scaffold

Rac-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}-3-phenylpyrrolidine-2-carboxylic acid is a chiral, stereospecific, cyclic sulfate that is synthetized by the reaction of glycol with lactam. It has been found to be effective against various types of cancer cells. Rac-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}-3-phenylpyrrolidine 2 carboxylic acid is an enantiopure compound that can be used as an intermediate in the synthesis of antiinflammatory drugs such as kainic acid.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Cis-4-hepten-1-ol is a volatile natural chemical compound that is found in many fruits and plants, such as apples, cherries, peaches, plums, and grapes. It is also used as a fragrance in perfumery. Cis-4-hepten-1-ol can be extracted by solid phase microextraction (SPME) or headspace techniques. This compound can be analyzed using gas chromatography with flame ionization detection (GC/FID). Cis-4-hepten-1-ol has been shown to have toxicological effects on living cells, such as causing DNA damage to human lymphocytes.

Versatile small molecule scaffold

Versatile small molecule scaffold

2-(4-Bromophenyl)-3-oxobutanenitrile (2BPOBN) is a heterocyclic compound that contains a benzene ring and an oxobutane moiety. It has been shown to have electron transfer properties, which can be used in organic electronics. 2BPOBN has been theoretically studied using the functional theory, which predicts its optical properties. Experimental results have shown that 2BPOBN absorbs light at wavelengths from 300 to 1000 nm and has a high extinction coefficient. This molecule also has intramolecular interactions, such as hydrogen bonding, dipole-dipole forces, and van der Waals forces. These interactions are important for determining the molecular structure of 2BPOBN. X-ray diffraction data has shown that the molecule is linear with an all trans geometry. The energy levels of the electrons in this molecule can be predicted by the nonlinear optical theory and experimental results show that it is an experimentally verified

Versatile small molecule scaffold

2-Benzylthiopropanoic acid is a primary alcohol that is an antimicrobial agent. It is a n-oxide, which means it contains the –O–O– group. 2-Benzylthiopropanoic acid has two isomers, alpha and beta. The alpha form has a sulfamic acid group and the beta form has a carboxylic acid group. 2-Benzylthiopropanoic acid can be used to treat gram-negative bacterial infections, such as those caused by Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, or Enterobacter cloacae. The most effective way to use this drug is as an aerosol for inhalation therapy in patients with cystic fibrosis or bronchiectasis who have had chronic lung infection. In addition to being an antimicrobial agent, 2-benzylthiopropanoic acid has been shown to have antiinflammatory

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

4-(Dimethylamino)benzenesulfonamide is a fluorescent dye used in analytical chemistry. It has been shown to be useful as a solvent for the separation of metal cations and anilines, as well as for the determination of binding constants. The fluorescence spectrum of 4-(dimethylamino)benzenesulfonamide is sensitive to metal cations and anilines, which can be used to determine their concentration. 4-(dimethylamino)benzenesulfonamide has a phenyl ring with amido groups that make it nonpolar, allowing it to dissolve in solvents such as acetonitrile. This molecule also binds to metal cations such as copper and zinc, which allows it to act as a sensor for those metals.

2-(2,4,6-Trichlorophenoxy)ethanol is a chlorinating agent that catalyzes the reaction of chlorine with hydroxyl groups to form hypochlorite. 2-(2,4,6-Trichlorophenoxy)ethanol can be used to produce chlorinated water or other disinfectants. It has been shown to have a weak estrogenic effect and has been found in the urine of animals treated with this compound. This chemical also binds to glucuronic acid and is excreted in the urine as a conjugate with glucuronide. The fixation of 2-(2,4,6-trichlorophenoxy)ethanol onto the imidazole ring of histidine residues can be inhibited by prochloraz and chloramine T.

2-Ethyl-4-methoxybenzaldehyde is an aromatic aldehyde that is used in the synthesis of estrogens. It can be synthesized by the Corey-Fuchs reaction between 2-methylphenol and ethyl acetoacetate. This product can also be reacted with bromine to produce bromoaldehydes, which have been used as estrogen analogues. The formylation of this compound produces formaldehyde, which is used in the elimination of steroids.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

8-Bromopyrido[3,4-b]pyrazine is a quinoxaline that binds to the active site of protein kinases and inhibits their activity. It has been shown to have potential as a drug against some forms of cancer. 8-Bromopyrido[3,4-b]pyrazine is also an arylboronic acid that can be used in copper catalysis. This compound has been optimized for use in kinase inhibition studies by modifying its structure to create analogues with different substituents. The family of compounds includes carbolines and anilines, which are related to 8-Bromopyrido[3,4-b]pyrazine by virtue of their structural similarity.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

2-(1H-Pyrazol-1-yl)benzonitrile is used as a catalyst for the synthesis of pharmaceuticals. It can be prepared by reacting pyrrolidine with aniline in chloroform. Pyrrolidine is then reacted with 2-chlorobenzonitrile and the resulting product, 2-(1H-pyrazol-1-yl)benzonitrile, is isolated from the reaction mixture by extraction with diethyl ether. The compound has a ligand that binds to metal ions and is also used as a chelating agent. This property allows it to catalyse reactions involving nucleophiles and halides. It can also be used in amino acid coupling reactions, yielding amides or imines, respectively.

Versatile small molecule scaffold

The mechanism of the cyclobutanone cleavage reaction is a sequential intramolecular process in which the first step is a cyclobutanol intermediate that undergoes an expansion to form a six-membered ring with two unsaturated bonds. The second step involves bond cleavage and is triggered by the presence of palladium. This sequence can be used to synthesize 3-(2-chlorophenyl)cyclobutan-1-one.

Versatile small molecule scaffold

Versatile small molecule scaffold

4-Chloro-6-ethylquinoline is a potential anticancer drug that inhibits the function of lysosomal enzymes and causes tumor cells to undergo necrosis. This drug has been shown to inhibit the growth of tumor cells in cell cultures, as well as in hypoxic tumor models. 4-Chloro-6-ethylquinoline inhibits the activity of lysosomal enzymes, which are necessary for the degradation and recycling of macromolecules and other substances within cells. It also binds to proteins on the surface of tumor cells, which prevents these proteins from functioning properly. The uptake of this drug is greater in extravascular tumor tissues than in blood vessels or normal tissue. In addition, it is taken up by tumor cells more readily than by normal cells. 4-Chloro-6-ethylquinoline binds with cytotoxins, causing them to become more cytotoxic and effective against cancerous cells. This compound has been shown to have medicinal

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Trans-3-ethoxycinnamic acid is a colorless liquid with a strong, pleasant odor. It is used in alkaline solutions as a dyeing and staining agent, as well as an insecticide. Trans-3-ethoxycinnamic acid can inhibit the growth of bacteria by disrupting the cell membrane and denaturing proteins. It can also be used to remove stains from clothing or dishware. This compound has been shown to be soluble in water and oil, but insoluble in benzene and diethyl ether. Trans-3-ethoxycinnamic acid reacts with ultraviolet light to produce fluorescent compounds that are used for staining DNA.

5-Bromo-2-cyclopropylpyrimidine is a chiral molecule that has two enantiomers. It can exist as a racemic mixture (a 50/50 mixture of the two enantiomers), or as an enantioenriched sample (containing one of the two enantiomers in large excess). The former is a mixture, whereas the latter is a single pure enantiomer. 5-Bromo-2-cyclopropylpyrimidine can be separated into its two components by using chiral columns and then analyzed by NMR spectroscopy. The individual peaks in the spectrum correspond to either one or the other of the two possible configurations.

Versatile small molecule scaffold

Versatile small molecule scaffold

MBP146-78 is a recombinant protein that acts as an immunomodulator. It is expressed in the form of a fusion protein with MBP, which is a bacterial antigen that is recognized by the immune system. MBP146-78 is designed to target parasitic protozoa such as tenella and leishmania. It has been shown to be effective against intracellular parasites such as toxoplasma and cgmp-dependent proteins. MBP146-78 has also been shown to have pharmacokinetic properties that are favorable for use in humans.

Versatile small molecule scaffold

Versatile small molecule scaffold

Trans-1,2-cyclohexanedimethanol is a synthetic compound that can be used for analytical chemistry. It has a variety of impurities and can form enantiomers and diastereomers when treated with an acid catalyst. Trans-1,2-cyclohexanedimethanol is also hydrophobic and can form chlorides, isomers, and epoxides by reacting with other compounds. Trans-1,2-cyclohexanedimethanol has been shown to have photocatalytic activity in the oxidation of organic substances.

Versatile small molecule scaffold

Versatile small molecule scaffold