Building Blocks

<p>Applications 5-(Trifluoromethyl)indolin-2-one is a useful reagent for the preparation of 3-Chloro-α-carbolines.<br>References Tian, S., et al.: Synlett, 29, 949 (2018)<br></p>

<p>Stability Air Sensitive, Light Sensitive<br>Applications Propargyl Sulfide (cas# 13702-09-5) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications n-Propyl-d7-benzene (CAS# 65087-58-3) is a useful isotopically labeled research compound.<br></p>

<p>Applications Propio-d5-phenone (CAS# 342610-99-5) is a useful isotopically labeled research compound.<br></p>

<p>Stability Hygroscopic<br>Applications Potassium propionate 98% (cas# 327-62-8) is a useful research chemical.<br></p>

<p>Applications 1-Methyl-3-pyrrolidinol (cas# 13220-33-2) is a compound useful in organic synthesis.<br></p>

<p>Stability Air Sensitive, Moisture Sensitive<br>Applications It is used for synthesis of unsymmetrical biaryls via aromatic C-H borylation-cross-coupling sequence.<br>References Stephens, T. et al.: Org. Lett., 19, 3498 (2017);<br></p>

<p>Applications (1S)-1-[4-(propan-2-yloxy)phenyl]ethan-1-amine (cas# 1212078-33-5) is a useful research chemical.<br></p>

<p>Applications Used in the preparation of 2-Aminodihydro[1,3]thiazines as BACE 2 inhibitors and their preparation and use in the treatment of diabetes.<br>References Ciayadi, R., et al.: Bioorg. Med. Chem. Lett., 21, 5642 (2011),<br></p>

<p>Applications 2-[(naphthalen-2-yloxy)methyl]oxirane is a monoesters of ibuprofen where are used as prodrugs with analgesic activity<br>References Soltani Rad. et al., Bioorg. Chem. 107, 104570(2021)<br></p>

<p>Applications 2,3,5,6-Tetramethylpyrazolo[1,2-a]pyrazole-1,7-dione (cas# 68654-22-8) is a compound useful in organic synthesis.<br></p>

<p>Applications 1-(4-Methoxyphenyl)ethanol (cas# 3319-15-1) is a useful research chemical.<br></p>

<p>Applications 2-PHENYLNICOTINIC ACID (cas# 33421-39-5) is a useful research chemical.<br></p>

<p>Applications A useful synthetic intermediate.<br></p>

<p>Applications 4-phenyl-2,3-dihydroquinazolin-2-one (cas# 23441-75-0) is a useful research chemical.<br></p>

<p>Stability No Data Availabe<br>Applications 2-(4-phenyl-1,3-thiazol-2-yl)acetamide (cas# 58351-19-2) is a useful research chemical.<br></p>

<p>Applications 6-Methyl-3-pyridineacetonitrile is a reactant used in the preparation of pyrazolopyrimidine derivatives as agents for treatment of autoimmune diseases and orally active corticotropin-releasing factor receptor antagonists.<br>References Chen, C. et al.: J. Med. Chem., 47, 4787 (2004)<br></p>

<p>Applications T62 is an allosteric enhancer of A1 adenosine receptor. T62 is useful in the treatment of patients with neuropathic pain.<br>References Kiesman, W. F., et al.: Handb. Exp. Pharmacol., 193, 25 (2009)<br></p>

<p>Applications 4-Phenylcyclohexanone is used in the synthesis of CCR2 antagonists for the treatment of rheumatoid arthritis, atherosclerosis and other disease states. Also used in the preparation of coumarins via dehydrogenation and Heck coupling reactions.<br>References Subasinghe, N. et al.: Bioorg. Med. Chem. Lett., 23, 1063 (2013); Kim, D. et al.: Chem. Comm., 49, 4021 (2013);<br></p>

<p>Applications 4-Methoxy-d3-toluene-2,3,5,6-d4 (CAS# 1219798-94-3) is a useful isotopically labeled research compound.<br></p>

<p>Applications 4-Methoxy(toluene-d7) (CAS# 1036431-36-3) is a useful isotopically labeled research compound.<br></p>

<p>Applications 1,1,1,2,2-Pentafluoro-4-iodobutane is a reactant in the synthesis of fluorous imidazolium chloride ionic liquids with the ability to dissolve cellulose.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Caes, B.R., et. al.: Green Chem., 13, 2719 (2011)<br></p>

<p>Applications 3-Methyl-2-thiophenecarboxaldehyde is used in the synthesis of 2,3-dimethyl-5-(2,6,10-trimethylundecyl)thiophene. It is also used to investigate versatile bioconversion capacity of baker′s yeast for the generation of thiols from cysteine-aldehyde conjugates.<br>References Sinnenghe, D., et al.: Tetrahedron Lett.,28, 957 (1987); Tuong, H., et al.: J. Agri. Food. Chem., 51, 3629 (2003)<br></p>

<p>Applications Methyl Phenylacetate is used as a reagent in the synthesis of various organic reactions, one of which is the synthesis of Vulpinic Acid (V850000); a lichen metabolite with anti-inflammatory properties.<br>References Shachak, M., et al.: Science, 236, 1098 (1987); Froberg, L., et al.: Lichenologist, 25, 83 (1993); Hesbacher, S., et al.: J. Chem. Ecology, 21, 233 (1995)<br></p>

<p>Applications 2,3-(Methylenedioxy)benzaldehyde (cas# 7797-83-3) is a useful research chemical.<br></p>

<p>Stability Moisture Sensitive<br>Applications Trifluoropyruvic Acid Ethyl Ester is used as a reagent in the preparation of potential biologically active compounds such as in the highly enantioselective organocatalytic hydroxyalkylation of indoles.<br>References Toeroek, B. et al.: Angew. Chem. Int. Ed., 44, 3086 (2005); Wolf, C. et al.: Adv. Synth. Cat., 353, 760 (2011);<br></p>

<p>Applications (2R,4S)-rel-4-Methyl-1,2-piperidinedicarboxylic Acid 1-(1,1-Dimethylethyl) Ester has been used in the preparation of homoproline (H605000), a GABA-uptake inhibitor derived from proline<br>References Dann, A., et al.: Nature, 186, 1051 (1960); Passreiter, C., et al.: Planta Med., 58, 556 (1992); Roeder, E., et al.: Pharmazie, 48, 953 (1993); Wernery, U., et al.: Fitoterapia, 68, 278 (1997)<br></p>

<p>Applications Pyridazinone derivatives are useful as intermediates for preparing compounds having excellent herbicidal activity.<br>References Hackler, et al.: J. Agric. Food Chem., 38, 508 (1990)<br></p>

<p>Stability Air Sensitive<br>Applications A useful synthetic intermediate for the preparation of novel antiinflammatory agents.<br></p>

<p>Applications 2-(5-Methoxybenzo[d]isoxazol-3-yl)acetic Acid (cas# 34172-98-0) could have agricultural applications specifically as a regulator for plant growth.<br>References Amorosi, S., et al.: Plant Growth Regul. Soc. Am., 22, 338 (1995)<br></p>

<p>Applications 4'-Methoxypropiophenone (cas# 121-97-1) is a compound useful in organic synthesis.<br>References Smith, H., et al.: Med. Chem., 3, 135 (2007), Trogden, B., et al.: Bioorg. Med. Chem. Lett., 19, 485 (2009),<br></p>

<p>Applications 2-Methylcoumaran is an impurity formed during the synthesis of metabolites of Diclofenac (D436450), a nonsteroidal anti-inflammatory compound an decycloxygenase (COX) inhibitor.<br></p>

<p>Applications 4-Methylcatechol-d8 (CAS# 1219803-18-5) is a useful isotopically labeled research compound.<br></p>

<p>Applications 4'-Methylacetophenone-d10 (CAS# 358730-83-3) is a useful isotopically labeled research compound.<br></p>

<p>Applications Tetramethyl-d12-urea (CAS# 51219-89-7) is a useful isotopically labeled research compound.<br></p>

<p>Applications Terephthaloyl chloride is used as a cross-linking agent to create polymers from various types of monomers.<br> E0<br>References Edwards-Lévy, F., et al.: Int. J. Pharm., 103, 253 (1994); Lee, J., et al.: Biomacromolecules, 7, 1729 (2006); So, Y.: J. Polym. Sci. Pol. Chem., Turska, E., et al.: J. Appl. Polym. Sci., 20, 1849 (1976)<br></p>

<p>Applications 5-Methyl-1,3-cyclohexanedione has been used in the synthesis of racemic (±)-fawcettimine and 3,6-dimethyl-2-phenylsulfanyl-3,5,6,7-tetrahydro-2H-benzofuran-4-one.<br>References Xin, L., et al.: Angewandte Chemie (International Edition), 46, 7671 (2007); Lee, Y., et al.: Korean Chem. Soc., 23, 1477 (2002)<br></p>

<p>Applications 4-Methylcyclohexanecarboxylic Acid Methyl Ester is the methyl ester derivative of 4-Methyl-cyclohexanecarboxylic Acid (M299530) and is used as a starting material in many organic reactions.<br>References Fedyanin, N. P., et al.: J. Appl. Chem-USSR+, 51, 375 (1978)<br></p>

<p>Applications 3-Methylcrotonic acid is used as a starting material to synthesize 3-Methylcrotonyl-CoA, an intermediate in the metabolism of Leucine.<br>References Anderson, M., et al.: Plant Physiol., 118, 1127 (1998); Hector, M., et al.: Biochemistry, 15, 3465 (1976)<br></p>

<p>Applications 4-Methylcyclohexanemethanol is patented for use as an ingridient of air fresheners. It can also be used to synthesize thiazolidinedione (2,4-thiazolidinedione, T344250) derivatives as 15-PGDH inhibitors.<br>References Wu, Y., et al.: Bioorg. Med. Chem., 18, 1428 (2010);<br></p>

<p>Applications 5-Methyl-pyrazine-2-carboxylic Acid (cas# 5521-55-1) is a compound useful in organic synthesis.<br></p>

<p>Applications 4-Nitrobenzenemethanol is a potential building block in the synthesis of various pharmaceuticals.<br>References Misra, K., et al.: J. Molec. Catalys. Enzymatic., 82, 92 (2012); Ashauer, R., et al.: Environ. Sci. Technol., 46, 4682 (2012);<br></p>

<p>Applications Methyl 2-Amino-5-bromobenzoate is used as a potential PqsD inhibitor against pseudomonas aeruginosa infections.<br>References Weidel, E. et al.: J. Med. Chem., 56, 6146 (2013);<br></p>

<p>Stability Moisture Sensitive - Store Under Inert Atmosphere<br>Applications 3-Methyl-8-quinolinesulfonyl Chloride (cas# 74863-82-4) is a compound useful in organic synthesis.<br></p>

<p>Applications 2-Mercaptoethanol (D6, 98%) (cas# 203645-37-8) is a useful research chemical.<br></p>

<p>Stability Dimerizes Readily - Store Under Inert Atmosphere<br>Applications 4-Mercaptobenzyl Alcohol, 90% (cas# 53339-53-0) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Stability Store Under Argon; Air Sensitive<br>Applications 4-Mercaptobenzoic Acid (cas# 1074-36-8) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References J. Org. Chem., 2835 (1962)<br></p>

<p>Applications 3-(4-Methoxyphenyl)-2-propynoic Acid (cas# 2227-57-8) is a useful reagent for preparing bis(phenylethynyl)benzenes.<br>References Ryu, B., et al.: Asian J. Org. Chem., 9, 1754 (2020)<br></p>

<p>Applications 5alpha-Androstan-17alpha-methyl-17beta-ol-3-one-1,2,4,5-d4 is a useful isotopically labeled compound of Mestanolone (M225790)<br></p>

<p>Stability Moisture Sensitive<br>Applications 4-Nitrobenzenesulfonyl Chloride is used in the preparation of N-Nosyl-α-amino acid for peptide synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Leggio, A. et al.: Tetrahedron, 63, 8164 (2007); Di Gioia, M.L. et al.: J. Org. Chem., 68, 7416 (2003);<br></p>

<p>Applications 5-METHYLPYRROLIDIN-3-OL (cas# 94134-94-8) is a useful research chemical.<br></p>

<p>Applications Malonic acid disodium salt monohydrate (cas# 26522-85-0) is a useful research chemical.<br></p>

<p>Stability Hygroscopic<br>Applications Malonic Acid-1,2,3-13C3 is labelled Malonic Acid (M158005) which is a small bioactive molecule, that can be used in variuos reactions. It is the classic example of a competitive inhibitor, which acts against succinate dehydrogenase (complex II) in the respiratory electron transport chain.<br>References Weiner, N., "Malonic acid", Org. Synth.; Coll. Vol. 2: 376;<br></p>

<p>Applications Malonic Acid-2-13C is labelled Malonic Acid (M158005) which is a small bioactive molecule, that can be used in variuos reactions. It is the classic example of a competitive inhibitor, which acts against succinate dehydrogenase (complex II) in the respiratory electron transport chain.<br>References Weiner, N., "Malonic acid", Org. Synth.; Coll. Vol. 2: 376;<br></p>

<p>Applications Labelled Malonamide (M158000). Malonamide is used in the synthesis of malonamic acid, malonamate and malonamide derivative of some heterocyclic compounds with antiinflammatory activity.<br>References Katagi T., et al.: Chem. Pharm. Bull., 33, 4878 (1985),<br></p>

<p>Applications Malonamide is used in the synthesis of malonamic acid, malonamate and malonamide derivative of some heterocyclic compounds with antiinflammatory activity.<br>References Katagi T., et al.: Chem. Pharm. Bull., 33, 4878 (1985);<br></p>

<p>Applications Maleimide (cas# 541-59-3) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Stability Hygroscopic, Moisture Sensitive<br>Applications Tosyl cyanide is a compound used as a cyanating and acylating agent in synthetic chemistry. Tosyl cyanide is also used as a reagent to synthesize cyanobutadiyne, a linear compound that is naturally found in various interstellar molecular clouds.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Abbas, S. &amp; Haines, A.: Carb. Res., 39, 358 (1975); Kirby, C., et al.: J. Mol. Spec., 83, 261 (1980); Skerlj, R., et al.: Bioorg. Med. Chem. Lett., 21, 262 (2011)<br></p>

<p>Applications Dodecanoic-2,2-d2 Acid (CAS# 64118-39-4) is a useful isotopically labeled research compound.<br></p>

<p>Applications 1,2,4,5-Tetramethylbenzene-d14 (CAS# 15502-50-8) is a useful isotopically labeled research compound.<br></p>

<p>Applications Dodecanoic-2-13C Acid (CAS# 287100-78-1) is a useful isotopically labeled research compound.<br></p>

<p>Applications 2-Methyl-1-phenyl-2-propanol is used in the preparation of (hydroisoquinolinylidene)acetic ureides with analgesic and antibacterial activities.<br>References Surikova, O. V., et al.: Pharm. Chem. J., 47, 198 (2013);<br></p>

<p>Applications Isoprene-2-13C is the labelled analog of Isoprene (I822300). Isoprene is used in the synthesis of rubber through a polymer synthetic route.<br>References Pugachov, V. et al.: Lat. J. Phys. Tech. Sci., 46, 56 (2009); Oprea, C. et al.: Polym. Plas. Tech. Eng., 27, 173 (1988)<br></p>

<p>Applications 2-Methylpropionyl-L-carnitine-d3 HCl (N-methyl-d3) is a useful isotopically labeled compound of Isobutyryl L-Carnitine Chloride (I780500)<br></p>