Building Blocks

<p>2-Chloro-5-phenyloxazole is an organic compound that belongs to the class of c2-6 alkenyl, acyloxyalkyl, and formyl compounds. It is also a carboxylic acid derivative. 2-Chloro-5-phenyloxazole has been shown to be active against bacteria such as Staphylococcus aureus and Pseudomonas aeruginosa. This drug has been shown to have antibacterial properties against a variety of organisms, including gram positive and gram negative bacteria.</p>

<p>Versatile small molecule scaffold</p>

<p>3-(3-Fluorophenyl)-2-(5-methyl-1H-1,2,3,4-tetrazol-1-yl)propanoic acid is a potent activator of GABAA receptors. It has been shown to have high affinity for GABA binding sites and is able to activate the receptor with an EC50 of around 100 nM. It also has no effect on other receptors that are structurally related to GABA, such as glycine and 5HT3 receptors. 3-(3-Fluorophenyl)-2-(5-methyl-1H-1,2,3,4-tetrazol-1-yl)propanoic acid is soluble in DMSO and ethanol.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>1-Bromo-2-fluoro-3-nitrobenzene is a synthetic chemical that is used as an intermediate in the synthesis of various dyes. It can be obtained by the diazotization of acetyl nitrite and acetonitrile, followed by acetylation with acetic anhydride and hydrolysis with sodium hydroxide. The bromoaniline formed after this reaction is then converted to 1-bromo-2-fluoro-3-nitrobenzene by refluxing it with nitric acid. This chemical can also be synthesized from bromines and chloride in the presence of a diazo salt. It reacts with fluoride or halogens to produce fluorobenzene derivatives, which are used as intermediates for other organic compounds.</p>

<p>Versatile small molecule scaffold</p>

<p>N-Methyl-4-phenoxyaniline is a molecule that inhibits chitinase, an enzyme that catalyzes the hydrolysis of chitin, and molting. N-Methyl-4-phenoxyaniline has been shown to be potent inhibitor of the enzyme amide in vitro. It also inhibits onchocerca volvulus and in vivo, which may be due to its ability to inhibit the synthesis of fatty acids. This drug has not been tested against other parasites or mammals, but it is an anthelmintic drug.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3-(Pyridin-2-yloxy)aniline is a synthetic compound that is used as a potent inhibitor of the enzyme tyrosine hydroxylase. This enzyme catalyzes the conversion of tyrosine to L-3,4-dihydroxyphenylalanine and plays a key role in the synthesis of dopamine. 3-(Pyridin-2-yloxy)aniline has been shown to be effective in treating Parkinson's disease and other disorders that involve neuronal degeneration and cell death. This drug inhibits the production of dopamine by binding to tyrosine hydroxylase, thereby preventing it from converting tyrosine into L-3,4-dihydroxyphenylalanine. The compound also has significant inhibitory activity against cyclin dependent kinases (CDKs), which are enzymes that regulate the activity of protein kinases.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>4-Bromo-1-hydroxynaphthalene-2-carboxylic acid (4BHN) is a spectroscopic compound that has been used as a radioligand to study the binding of dopamine and dopamine D3 receptors. This compound binds to the d3 receptor with high affinity and specificity, but it does not interact with the d1 or d2 receptors. 4BHN has been shown to act as an agonist at the dopamine D3 receptor. It also acts as an antagonist at the piperidine site of the dopamine D2 receptor. The effects of 4BHN are reversible, which means that it can be displaced by unlabeled 4BHN or other compounds that bind to the same site on the receptor. This technique is useful for studying drug interactions and for determining whether drugs have a subtype selectivity profile.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-Hydroxy-4-(phenylmethoxy)benzoic Acid Methyl Ester is a benzene derivative that inhibits the binding of xanthones to the benzene ring in a variety of ways. This compound is formed by reacting phenol with methyl benzoate in the presence of acid and heat. The low energy ligand inhibits the binding of xanthones to benzene by forming hydrogen bonds, covalent bonds, or van der Waals forces with the anion. 2-Hydroxy-4-(phenylmethoxy)benzoic acid methyl ester has shown anti-inflammatory properties, which may be due to its ability to inhibit leukocyte adhesion at inflammatory sites.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>