Building Blocks

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Ethyl 5-methylfuran-2-carboxylate is a feedstock that is used in the production of additives for lubricants. Ethyl 5-methylfuran-2-carboxylate has been shown to have high thermal stability, excellent lubricity, and good resistance to oxidation. This feedstock has also been found to be compatible with alkoxycarbonyl groups and can be used as an additive for gasoline. The synthesis of this compound involves the alkylation of pyrrole using ethyllithium followed by dehydration, which leads to a high yield of this compound.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3,4-Dichloro-2-hydroxybenzoic acid is a byproduct of the chlorination of carbon tetrachloride and 2,6-dichlorobenzoic acid. It can be used as an intermediate in the production of polyphosphoric acid. 3,4-Dichloro-2-hydroxybenzoic acid has been shown to have high yields and processability for use in polymer manufacturing. This active substance has also been shown to exhibit antibiotic activity against Staphylococcus aureus, which may be due to its ability to inhibit protein synthesis.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3-Ethyloxolane-2,5-dione is a polymerization initiator that is used in the production of polymers and sealants. Its main application is for the production of polycarboxylic acid ester resins, which are monosubstituted with an ethyloxolane group. 3-Ethyloxolane-2,5-dione reacts with aluminium chloride to form a hydrochloric acid salt. This polymerization initiator also reacts with hydrogen chloride to form a monomer that is soluble in organic solvents. It has been shown to be biodegradable and not toxic to humans or animals at low doses.</p>

<p>3-(2-Methylpropyl)oxolane-2,5-dione is a synthetic drug that inhibits bone resorption and is used as an anti-inflammatory agent. It has been shown to have a synergistic effect with calcium carbonate in the prevention of restenosis. 3-(2-Methylpropyl)oxolane-2,5-dione also inhibits gelatinase activity and has been shown to be effective against cancer cells.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-(Hydroxymethyl)pyridin-3-ol is a pyridine derivative that has been shown to be an acetylcholinesterase inhibitor. It is used to treat tuberculosis and other bacterial infections. 2-(Hydroxymethyl)pyridin-3-ol binds to the active site of acetylcholinesterase, which leads to the inhibition of its activity. This drug also inhibits uptake of pyridines into cells, as well as uptake into mitochondria. In addition, it inhibits uptake of drugs by lung tissues and erythrocytes.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>4-Ethyl-2,6-dimethoxyphenol is a monomer that belongs to the group of phenols. It is used as a catalyst in the production of polyurethane foam and other catalytic processes. The molecular weight is 176.4 g/mol, with a melting point of 36°C and boiling point of 285°C. 4-Ethyl-2,6-dimethoxyphenol is also used in treatments for low molecular weight organic compounds such as methanol, phenolic, and hydrogenolysis. This monomer has been shown to be an effective catalyst for the industrial production of polyurethane foam and various other catalytic processes. The yield from 4-Ethyl-2,6-dimethoxyphenol ranges from 60% to 90%.</p>

<p>Versatile small molecule scaffold</p>

<p>Ethyl 2-(3-chlorophenyl)acetate is an orally active small molecule that has been shown to have a potent immunosuppressive activity in mice. It inhibits the production of antibodies and T cells by binding to the antibody-producing cells in the spleen. Ethyl 2-(3-chlorophenyl)acetate also blocks the production of interleukin-4, which is important for eosinophil activation, and it can be used for asthma treatment. This compound is a competitive antagonist of histamine H1 receptors and has been shown to be a bronchodilator in murine models of asthma.</p>

<p>Versatile small molecule scaffold</p>

<p>4-Methoxy-3-methylphenol is a phenolic compound that is used as an intermediate in the production of other organic compounds. It has been shown to be bactericidal against Staphylococcus aureus and Salmonella typhimurium, but not against Escherichia coli. 4-Methoxy-3-methylphenol can be synthesized by hydrolysis of 3,4-dimethoxyphenol with sodium hydroxide solution. This reaction produces alkoxyphenols and oxidation products such as 4-hydroxybenzaldehyde and 4,5-dihydroxymethyl phenylcarbinol. The mass spectrometric detection of this compound can be achieved through the use of electron ionization or chemical ionization techniques.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Longimamma is a natural product that was first isolated from the Mexican plant Mammillaria. This compound has a chemical structure that is similar to that of the hallucinogen mescaline, which is found in the peyote cactus. Longimamma has been shown to have an inhibitory effect on monoamine oxidase-A and serotonin reuptake, suggesting potential therapeutic use for depression and other mental disorders.</p>

<p>4-Chloro-2-phenyl-pyrimidine is a synthetic compound that has been shown to be effective against bacterial strains resistant to other antibiotics. 4CPP is an amide with a chloro group at the 2 position and a pyridine ring at the 4 position. It has been shown to inhibit bacteria by binding to the molecule and preventing its function. This binding causes cell death by inhibiting protein synthesis and DNA replication. 4CPP also undergoes phototransformation when exposed to ultraviolet light, which may lead to increased efficacy of this drug in vivo.4CPP is synthesized from 2,4-dichloropyrimidine, which reacts with an amine in acidic conditions. The substituent effects on the aromatic rings are important for determining reactivity of this molecule.END&gt;&gt;</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>This compound is a model for the study of hydroxyapatite. The (4S)-4-benzyl-1,3-oxazolidine-2,5-dione has been shown to be an effective macroinitiator for ring-opening polymerization. It can be used as a biological marker for bone growth factor. The compound has also been shown to have antiinflammatory properties in both animal and cell culture studies.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3-Iodopropyltrimethoxysilane is a multifunctional silane that can be used for the synthesis of polymers with a variety of properties. It reacts with hydroxyl groups, amines, and carboxylic acids to form esters, amides, or urethanes. 3-Iodopropyltrimethoxysilane has been shown to have an uptake in the range of 10-10 mol/L under physiological conditions and has been found to be stable in biological studies. This compound is reactive with hydrogen ions and proton sources such as hydrochloric acid. 3-Iodopropyltrimethoxysilane has been shown to exhibit Toll-like receptor 4 (TLR4) specificity when used as a treatment for nitrogen atoms. The reaction mechanism of this compound is not well understood but it has been proposed that it may involve electrochemical impedance spectroscopy.</p>

<p>2,3-Dihydroxy-2-methylbutanoic acid is a flavonoid that has been shown to have acetylation and ion exchange properties. It is also an enantiopure compound that can be synthesized by techniques including chemoenzymatic or kinetic techniques. 2,3-Dihydroxy-2-methylbutanoic acid can be prepared as either of two stereoisomers, which are dihydroxydimethylbutanoic acid and dihydroxyacetoacetic acid. The synthesis of this substance is typically carried out by trimethylation of the corresponding 3-hydroxypropanoic acid with an ethyl halide followed by hydrolysis of the ester group.</p>

<p>Versatile small molecule scaffold</p>

<p>Benzenepropanol, 2-methyl- is an alkoxide that has an X-ray transition and a low reactivity. It can be classified as a polymeric material because of its evolution and chemical composition. The 2-methyl group in the benzenepropanol molecule is responsible for the gelation of this material. Small angle x-ray scattering (SAXS) shows that benzenepropanol, 2-methyl- has a fractal dimension of approximately 1.6. This material's solvents are alkoxides, which can be dissolved in benzene and cyclohexane.</p>

<p>3-Bromo-2-furoic acid is an intermediate in the synthesis of 3,4-dihydro-2H-pyran. It is produced by the oxidation of 2-furoic acid and can be synthesized by the reaction of furyl with biphenyl. 3-Bromo-2-furoic acid is a competitive inhibitor of glutamate dehydrogenase and glutamate synthetase. Inhibition of these enzymes prevents the conversion of glutamate to glutamine, which leads to elevated levels of glutamate in the brain, resulting in neurotoxicity. 3-Bromo-2-furoic acid also inhibits nicotinic acetylcholine receptors at low concentrations and has been shown to inhibit mitochondrial respiration. This drug has been used to treat hypertension in rats.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Methyl 2,6-dichlorobenzoate is a nitro compound with a synlett isomeric amide. It was synthesized by reacting methyl benzoate with nitric acid to form the corresponding nitro compound which was then hydrolyzed to give the desired product. The molecule has two conformers and two geometries, one of which is non-polar and the other polar. The non-polar conformer has electron densities that are higher than those in the polar conformer.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

3-Ethyl-2-methyl-1,3-benzothiazol-3-ium 4-methylbenzene-1-sulfonate is a tosylate salt that is used in organic synthesis. It is a mesoionic compound that can be prepared by the reaction of benzaldehyde with sodium methylsulfinate and ethyl iodide. This compound has been shown to react with anhydrides such as acetic anhydride and pivaloyl chloride to form esters.

<p>Versatile small molecule scaffold</p>

<p>2,3,4,5-Tetrahydro-1,4-benzothiazepin-5-one is a crystalline dimer that has a seven membered ring and two hydrogen bonds. The conformation of the molecule is centrosymmetric and the crystal structure has been determined by X-ray diffraction.</p>

<p>3-Methyl-1,2,3,4-tetrahydronaphthalen-1-one is a methylated natural product. It is synthesized by the metalation of 1,2,3,4-tetrahydronaphthalene with methyl iodide and zinc. This reaction proceeds in two steps: first the ortho hydrogen of 1,2,3,4-tetrahydronaphthalene is replaced by the methyl group and then the nitrogen atom is alkylated. The formation of 3-methyl-1,2,3,4-tetrahydronaphthalen-1-one can be explained by an S N 2 substitution reaction in which a hydrogen on the methyl group attacks the electron deficient carbon atom of 1,2,3,4 tetrahydronaphthalene. 3-Methyl-1,2,3 4 tetrahydronaphthalen 1 one has been shown to</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>4-Amino-4'-hydroxybenzophenone is a benzophenone with a hydroxyl group in the ortho position. It has absorption spectra that are similar to those of benzene, but it is less soluble in solvents and more soluble in water. The molecule has two possible conformations, both of which have an equilibrium constant (K) of 10. The two conformations can interconvert by rotation about the C=C bond, which is referred to as torsion. This conformational change in the molecule alters its light absorption properties.</p>

<p>4-Methoxyisobenzofuran-1,3-dione is a natural product that belongs to the group of hydroxybenzoic acids. It is obtained by the hydrogenation of 3-nitrophthalic anhydride and 3-hydroxyphthalic anhydride, which are obtained from anacardic acid. 4-Methoxyisobenzofuran-1,3-dione has been used as an intermediate for antibiotics and synthetic dyestuffs. The chloride salt of this compound has been used as a reagent in organic synthesis.</p>