Building Blocks

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3,4-Dimethoxy-5-nitrobenzoic acid is a compound that can be used in the synthesis of pharmaceuticals. It has been shown to inhibit methylene amide demethylation and may have potential as an inhibitor of the enzyme catechol-o-methyltransferase. 3,4-Dimethoxy-5-nitrobenzoic acid is also used as a synthetic intermediate in the preparation process for other compounds. This chemical is bifunctional, with one functional group being electron rich and the other electron poor. The two functional groups are connected by a spacer molecule. Potassium is often used to prepare this chemical from its corresponding potassium salt.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-Methyl-6-(3-methylbutyl)pyrazine is a ketone that has been used as an active compound in the flavorings industry. It also has industrial applications and can be found in carboxylic acid mixtures, flavoring, and hydrocarbon mixtures. 2-Methyl-6-(3-methylbutyl)pyrazine is used to synthesize other compounds, such as trimethylphenol, which is used as a rubber antioxidant. Nephelium lappaceum (tree) extracts have been shown to contain high concentrations of this chemical.</p>

<p>2,6-Dipropyl-3,4-dihydropyrimidin-4-one is an analytical reference standard that is a plant derived secondary metabolite. It is used in research and development to produce HPLC standards and as a quality control material for screening purposes. The compound has been isolated from the roots of a variety of plants, including the root of the Chinese medicinal herb Angelica sinensis.<br>2,6-Dipropyl-3,4-dihydropyrimidin-4-one has been studied for its antiinflammatory properties and found to inhibit prostaglandin synthesis.</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>7-Chloro-4-(2-hydroxyethyl)aminoquinoline (7CQ) is a biotransformation product of the 7-chloro-4-(2-hydroxyethyl)aminoquinoline (7CEA). It is an inhibitor of hydrolase enzymes, which are used by microorganisms to produce cell walls. 7CQ has been shown to inhibit the growth of bacteria in cell free assays and also inhibits mutants that have acquired resistance to other antibiotics. This compound has been produced using recombinant DNA techniques and is a useful tool for studying microbial physiology.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3-Phenylcyclopentane-1-carboxylic acid (3PC) is a metabolite of the anticancer drug cyclopentane. 3PC inhibits mammalian cell growth in vitro and in vivo. This compound has also been shown to inhibit the activity of a number of enzymes, including cyclopentane hydrolase, cytochrome P450, and glutathione reductase. The anticancer properties of 3PC are thought to be due to its ability to inhibit steroid hormone biosynthesis or the synthesis of other cellular components that may be important for cancer cell growth.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>1-(5-Thiazolyl)ethanone is an antimicrobial agent that has been shown to be active against staphylococcus and other bacteria. It is a nucleophilic reagent that reacts with the amine group of amino acids in proteins, which leads to the formation of protein adducts. 1-(5-Thiazolyl)ethanone has been found to be safe for use in humans and animals and does not have any significant side effects. The chemical is also able to kill cancer cells by inhibiting DNA synthesis, RNA synthesis, and protein synthesis. This drug has been shown to have antibacterial activity against a number of different bacterial strains, including methicillin-resistant Staphylococcus aureus (MRSA) isolates.</p>

<p>8-Methoxychroman-3-one is a carboxylic acid that has been chemically modified to contain an acrylonitrile group. It can be synthesized by the reaction of nitric acid and glycidyl methacrylate. 8-Methoxychroman-3-one is used as a building block in organic synthesis. It is also used as a precursor for the production of other chemicals, such as dyes and pharmaceuticals. This compound can be converted to optically active forms by reacting with an optically active amine such as (S)-(-)-2-(tert-butyldimethylsilyl)azide or (R)-(+)-2-(tert-butyldimethylsilyl)azide. 8-Methoxychroman-3-one can be hydrolyzed with an aluminum alkoxide to produce glycidol, which is used in the production of polyureth</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3-Methyl-4-nitrophenylhydrazine is a metabolic product of clozapine and has been found to be a potent neuroleptic agent. 3-Methyl-4-nitrophenylhydrazine has been shown to inhibit the uptake of dopamine by binding to the dopamine transporter, which leads to an increase in dopaminergic activity. This compound also inhibits the synthesis of polyphosphoric acid, which may be due to its ability to act as an antidopaminergic agent.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>4-Chloro-N,N-dimethylquinazolin-2-amine is a silicone that is used as an active substance in polydimethylsiloxane. It has a cyclic structure and transesterification reaction with alkanoic acid. This active substance has hydrophobic properties that make it suitable for use in deodorizing and encapsulated products. 4-Chloro-N,N-dimethylquinazolin-2-amine also has the ability to react with alcohols to form esters, which can be used as solvents or fragrances.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>4-Hydroxy-2-[4-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)phenyl]acetic acid (4HDPA) is a small molecule that is being studied for its anticancer properties. 4HDPA is a prodrug that is converted to 2-[4-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)phenyl]acetic acid (4DPA), which has been shown to inhibit the growth of lung carcinoma cells in vitro and in vivo. 4DPA inhibits the proliferation of cancer cells by inhibiting the production of proteins vital for cell division. It also blocks the uptake of glucose and amino acids by cancer cells. 4HDPA has been shown to cause apoptosis in cancer cells by activating caspase 3 and 8, which are enzymes involved in cellular death.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2,6-Dichloro-4-methylpyridine-3-carbaldehyde is a photochromic compound that undergoes electrocyclization in the presence of UV irradiation. This reaction produces a transient intermediate that has two different forms: one is colorless and the other has a blue color. The reaction can be reversed by exposure to visible light or by heating.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>1-Cyclohexyl-4-iodobenzene is a chemical that reacts with solvents to form diaryliodonium salts. It is soluble in acetone, ethanol, and benzene but not in water. The reaction rate is affected by the solvent used as well as the concentration of 1-cyclohexyl-4-iodobenzene.</p>

<p>Versatile small molecule scaffold</p>

<p>1-Benzyl-5-methylpyrrolidin-2-one is a catalyst that can be used in the reductive amination reaction. It is an ionic liquid that has been immobilized on a graphene oxide surface. This catalyst is also able to catalyze the cyclization of ammonia, amines, and alcohols. 1-Benzyl-5-methylpyrrolidin-2-one can be recycled for use in other catalytic reactions by first reducing it with ruthenium metal ions in an ionic liquid. The reactivity of this catalyst is dependent upon the nature of the metal ions present and their concentration.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>4-[(Thiophen-2-yl)methyl]phenol is a compound that inhibits the uptake of serotonin in the brain and has been shown to act as an antinociceptive and an anti-inflammatory. It also inhibits inflammatory bowel disease. 4-[(Thiophen-2-yl)methyl]phenol has been shown to be orally active, acting on 5HT uptake. This drug has also been shown to be an active inhibitor of leukotriene A4 (LTA4), which is the precursor for leukotrienes that are involved in pain signaling, inflammation, and asthma.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>