Building Blocks

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>8-Bromo-4H-chromen-4-one is a halogenated aromatic compound that inhibits the growth of gram-negative bacteria. 8-Bromo-4H-chromen-4-one has been shown to inhibit the growth of gram negative bacteria by binding to their DNA. This binding prevents the synthesis of proteins and other cellular components, leading to bacterial death.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Benzo[d]thiazole-4-carboxylic acid is a potent inhibitor of dihydroorotate dehydrogenase (DHODH), an enzyme that catalyzes the conversion of dihydroorotate to orotic acid. DHODH inhibitors are being investigated for their potential use in cancer treatment. Benzo[d]thiazole-4-carboxylic acid may be used as a lead compound in the development of new anti-cancer drugs. This inhibitor has been validated in vitro and in vivo and has shown efficacy against human cancer cell lines. These properties have been confirmed by a number of computational methods, including pharmacophore modeling and molecular docking simulations.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Dimethallylamine is a monomer that can be used as a polymerization initiator. Dimethallylamine has been shown to react with hydrochloric acid in an efficient method for the synthesis of polydimethylsiloxane. Dimethallylamine reacts with fatty acids to form esters and amines, which are structural components of many polymers. Dimethallylamine can also be used as a cross-linking agent in cellulose derivatives such as nitrocellulose and cellulose acetate butyrate.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>N-Ethylpyridin-4-amine is an aminopyridine that interacts with chloride ions to form a specific chloroformate ester. It is used as a biochemical tool for the detection of lead in biological samples. The reaction time for the formation of the chloroformate ester is dependent on concentrations, pH, and temperature. This compound can be extracted from other compounds using a variety of different extraction techniques. The asymmetry of N-Ethylpyridin-4-amine can be detected using various spectroscopic techniques such as infrared or nuclear magnetic resonance spectroscopy.</p>

<p>4-Bromo-2,1,3-benzoxadiazole (4BB) is a mycobacterium avium inhibitor. It has been shown to inhibit the growth of Mycobacterium avium and other bacteria by binding to the chemokine receptor CXCR1. 4BB inhibits chemokine-induced migration of inflammatory cells, which may be due to its ability to inhibit tnf-α production in human lung cells. This drug also has been shown to have antiinflammatory effects, which are mediated through the inhibition of prostaglandin synthesis at the cyclooxygenase enzyme. 4BB is not active against bacteria that are resistant to beta-lactam antibiotics or fluoroquinolones.</p>

<p>Versatile small molecule scaffold</p>

<p>1,2,3,4,5,6,7,8-Octahydroquinazoline-2,4-dione is a bicyclic compound that has high potency as an antagonist at the 5HT2A receptor. This compound is orally active and has been shown to be effective against ketanserin in vitro. The bicyclic ring system of 1,2,3,4,5,6,7,8-octahydroquinazoline-2,4-dione provides the molecule with a high degree of lipophilicity and this may account for its potent activity.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

N-[(4-Methoxyphenyl)methyl]acetamide is a photocurrent generating compound that is used in the production of pyroglutamic acid. It has been shown to be efficient under irradiation and can be used for the photooxidation of organic compounds. The efficiency of this compound has been shown to increase with annealing, which may be due to its chirality. N-[(4-Methoxyphenyl)methyl]acetamide is also a crystalline solid that can be used as an anode material in photoelectrochemical devices.

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Ethyl 1-bromocyclobutanecarboxylate is a reactive compound that is used in the synthesis of various organic compounds. It can be prepared by the reaction of an alkyl bromide with a ketone, followed by hydrolysis of the ester group. This product is also used in biomolecular chemistry as a reactant for synthesizing oxindoles and anilines. It is oxidized to yield aldehydes and ketones. The oxidation reaction mechanism begins with the formation of an unstable ethyl radical which abstracts hydrogen atoms from neighboring molecules to form a secondary radical. This secondary radical then reacts with molecular oxygen to produce H2O2, which then reacts with another molecule of ethyl 1-bromocyclobutanecarboxylate to produce peroxy radicals (RO•) and alcohols.</p>

<p>Versatile small molecule scaffold</p>

<p>2-Chloromethyl-pyrrolidine hydrochloride is an organic compound with the chemical formula CHClNCHCOH. It is a white solid that can be used as a reagent in organic synthesis. 2-Chloromethyl-pyrrolidine hydrochloride is prepared by the reaction of chloroform and pyrrolidine. The product is purified by recrystallization from ethanol and dithionite, followed by alkaline hydrolysis.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3,5-Diiodoanaline is a crystalline solid. It is synthesized by the reaction of phenylhydrazine and hydrogen peroxide in acetonitrile. The product is purified by gel permeation chromatography and characterized using X-ray crystallography. 3,5-Diiodoanaline has two optical isomers and a melting point of 133-135 °C. 3,5-Diiodoanaline has been used to produce amides that are unsymmetrical with respect to the carboxylic acid and amine groups. This chemical can also be used as a peroxide or functional group for synthetic reactions.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>5,6,7,8-Tetrahydroquinoxalin-5-ol is a chiral compound that can be used to synthesize carboxylic acid derivatives. It is prepared by the catalytic hydrogenation of 5-(hydroxymethyl)tetrahydroquinoxaline-2,3(1H)-dione (1). The enantiomeric purity of this compound can be determined by its reaction with sulfuryl chloride in hydrochloric acid (HCl) to yield the corresponding sulfonyl chloride. This reaction forms an asymmetric sulfonamide that can then be separated by crystallization.</p>

<p>Chlorpromazine is a potent antipsychotic drug that is used to treat mental disorders such as schizophrenia and bipolar disorder. It works by blocking the action of dopamine, a neurotransmitter in the brain. Chlorpromazine has minimal acute toxicity in animals and low potential for abuse or addiction. The most common side effects are drowsiness, dry mouth, nausea, and sedation. Chlorpromazine can interact with other drugs such as diazepam or chlorodiazepoxide to produce an anxiolytic effect. It also interacts with analgesics to produce depressant effects by increasing their sedative properties. In monkeys, chlorpromazine has been shown to have anxiolytic efficacy and depressant effects when given at high doses.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-(Pentylamino)ethan-1-ol is a hydric compound that contains an ethanolamine group. It has antibacterial properties and reacts with polyvinyl chloride, which can produce reactive compounds. 2-(Pentylamino)ethan-1-ol is also used as a reactive ingredient in the synthesis of polyvinyl alcohols and polyvinyl acetates. The hydroxyl group on the molecule reacts with aromatic hydrocarbons, such as benzene, to form a cationic surfactant. This product is used in textile production to enhance dyeing and printing processes.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3-(Chloromethyl)-5-methylisoxazole is an organolithium reagent that is used for the synthesis of a variety of complex organic compounds. 3-(Chloromethyl)-5-methylisoxazole is a versatile reagent that can be used in metallation reactions, cycloadditions, and selective transformations. The selectivity of this reagent has been shown to be due to its ability to form stable organolithium compounds with heteroatoms such as oxygen and nitrogen.</p>

<p>Versatile small molecule scaffold</p>

<p>-2(5-Methylisoxazol-3-Yl)Acetonitrile is a heterocyclic compound that is used as a catalyst in cross-coupling reactions. It can be utilised for the synthesis of aromatic heterocycles and tosylate derivatives. -2(5-Methylisoxazol-3-Yl)Acetonitrile is an analogue of 2,5-dimethylisoxazole, and it can be used as a synthetic intermediate for the synthesis of various pharmaceuticals.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>N-(2-Hydroxyethyl)-N-methyldodecanamide is a surfactant that is used in cosmetics for its ability to form micelles and solubilize fatty acids and oils. It is a hydrophobic molecule with a high viscosity, which makes it suitable for use in products such as shampoos, body lotions, and face creams. N-(2-Hydroxyethyl)-N-methyldodecanamide can also be used as an emulsifier in the preparation of foods such as mayonnaise, salad dressings, and whipped cream. This compound has been shown to be toxic to the worm Caenorhabditis elegans at concentrations above 10%.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>4-(3-Pentyl)pyridine is a colorless and odorless liquid that is soluble in organic solvents. It has been shown to be a good solvent for many organic compounds, such as the acetonitrile, and has a high boiling point. 4-(3-Pentyl)pyridine can also undergo photolysis and thermally induced reactions, which may make it suitable for use as an additive in solar cells.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>