Building Blocks

<p>Stability Hygroscopic<br>Applications 4-O-Methyl-D-glucuronic acid (cas# 2463-49-2) is a useful research chemical.<br></p>

<p>Stability Hygroscopic<br>Applications A useful intermediate in the synthesis of polypeptides.<br>References Gobbini, M., et al.: J. Med. Chem., 51, 4601 (2008),<br></p>

<p>Applications A benzoic acid derivative used in photolysis reactions and biomaterial studies.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Wetzels, G.M. et al.: Biomaterials., 20, 1879 (1999); Mao, C. et al.: Adv. Coll. Int. Sci., 110, 5 (2004);<br></p>

<p>Stability Moisture Sensitive, Very Hygroscopic<br>Applications A Cyclophosphamide analog which induces apoptosis dose and time dependently in lymphoblastoid cells, with clearly more apoptosis in p53wt cells. Antitumor agent.<br>References Roy, P., et al.: Drug Metab. Dispos., 27, 655 (1999), Lips, J., et al.: Carcinogenesis, 22, 579 (2001), Ward, I., et al.: J. Biol. Chem., 276, 47759 (2001), Zhou, B., et al.: Cancer Biol. Ther., 2, S16 (2003), Roos, W., et al.: Oncogene, 26, 186 (2007),<br></p>

<p>Applications Malonic Acid, is a small bioactive molecule, that can be used in variuos reactions. It is the classic example of a competitive inhibitor, which acts against succinate dehydrogenase (complex II) in the respiratory electron transport chain.<br>References Weiner, N., "Malonic acid", Org. Synth.; Coll. Vol. 2: 376;<br></p>

<p>Applications 2-ethylbenzamide (cas# 67832-97-7) is a useful research chemical.<br></p>

<p>Applications 4-Amino-1-naphthalenesulfonic acid has potent therapeutic applications. Its sodium salt has been used as non-toxic hemostatic. It is also a metabolite of azo dyes.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Alonso, M., et al.: Anal. Chim. Acta, 400, 211 (1999); Chung, K., et al.: Appl. Environ. Microb., 42, 641 (1981)<br></p>

<p>Applications 1-Methyl-1H-pyrrole-2-carbaldehyde is a substance for the toxicological evaluation of aerosols of a tobacco extract formulation and nicotine formulations in acute and short-term inhalation studies. A substance for ligand-based screening of chemical constituents of Glycyrrhiza glabra in search of inhibitors of xanthine oxidase.<br>References Werley, M. S., et al.: Inhalation Toxicology, 26, 207 (2014); Naeem, S., et al.: Int. J. Biol. Biotechnol., 9, 257 (2012)<br></p>

<p>Applications Alizarin is used widely as a prominent red dye for textile facbrics. Alizarin red is now used in biochemical assay to determine quantitatively by colorimetry, the presence of calcific deposition by cells of the osteogenic lineage. Alzarine derivatives was evaluated as new inhibitors of the HIV-1 reverse transcriptase associated DNA polymerase and RNase H. Alizarin was also shown to inhibit proliferation, tumor growth and suppress tumorigenesis in human osteosarcoma and breast cancer cell representative for bone metastasis. Dyes and metabolites.<br>References Yuan, H.S., et al.: Mycol., 3, 100 (2012); Esposito, F. et al.: FEBS. J., 278, 1444 (2011); Fotia, Caterina, J. Orthop. Rsch. 30, 1486 (2012);<br></p>

<p>Applications 6,7-Dimethoxyisoquinoline is used as an organocatalyst in the chemoselective O-tert-butoxycarbonylation of phenols.<br>References Saito, Yukako, et al.: Tetrahedron Let., 51(52), 6915-6917 (2010)<br></p>

<p>Applications 3-Methylnonane-2,4-dione is a compound that possesses a butter-like and beany off flavour that is a result of flavour reversion of soya-bean oil. 3-Methylnonane-2,4-dione is also present in Japanese green tea and pressure-cooked hen meat.<br>References Farkaš, P., et al.: Food Chem., 60, 617 (1997); Guth, H. &amp; Grosch, W.: Flav. Chem., No vol. given, 377 (1999); Kumazawa, K. &amp; Masuda, H.: J. Agr. Food Chem., 47, 5169 (1999)<br></p>

<p>Applications 4-Methyl-2(5H)-furanone (cas# 6124-79-4) is a useful research chemical.<br></p>

<p>Stability Light Sensitive<br>Applications 1-Vinylimidazole (cas# 1072-63-5) is a useful research chemical.<br></p>

<p>Applications L-Histidine is an essential amino acid for human development which the body cannot produce on its own. L-Histidine is one of the 22 proteinogenic amino acids. L-Histidine precursor to histamine (H436500) and a component of carnosine.<br>References Kopple, J.D. et al.: J. Clin. Invest., 55, 881 (1975); Sachs, D.H., et al.: J. Biol. Chem., 246, 6576 (1971); Mercer, L.P., et al.: Nutrition, 6, 273 (1990); Morgan, W.T., et al.: J. Biol. Chem., 268, 6256 (1993);<br></p>

<p>Applications 2-Sulfobenzoic Anhydride (cas# 81-08-3) is a useful research chemical.<br></p>

<p>Applications Hexadecanoic-9,9,10,10,11,11,12,12,13,13,14,14,15,15,16,16,16-d17 Acid (CAS# 81462-28-4) is a useful isotopically labeled research compound.<br></p>

<p>Applications Euscaphic Acid is a hypoglycemic natural product from Folium Eriobotryae with anti-inflammatory properties. Euscaphic Acid also downregulates NF-κB activations and inhibits LPS-induced inflammatory responses.<br>References Chen, J., et al.: Pharmazie. 63, 765 (2008); Kim, I. T., et al.: J Cell Biochem. 113, 1936 (2012)<br></p>

<p>Applications 5-Chloro-1,2-benzisothiazol-3(2H)-one (cas# 4337-43-3) is a compound useful in organic synthesis.<br></p>

<p>Applications 2,4-Thioxylenol is a building block that has been used as a reactant for the preparation of Dibenzothiophene derivatives via palladium catalyzed aryl(alkyl)thiolation of unactivated arenes.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Saravanan, P., Anbarasan, P.: Org. Lett., 16, 848 (2014)<br></p>

<p>Applications Succinic Acid derivative.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications Bromocyclopropane (cas# 4333-56-6) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 1-Chlorododecane is used as a reagent in the chemical modification of zein to reduce the brittleness of zein films.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Shi, K., et al.: J. Agr. Food Chem., 59, 56 (2011)<br></p>

<p>Applications DL-Isocitric Acid Lactone (cas# 4702-32-3) was identified as a component in Aloe vera leaves and commercial aloe juice powders.<br>References Zhang, Y., et al.: J. AOAC, 101, 1741 (2018)<br></p>

<p>Applications 3-Methyl-2-oxovaleric Acid is an α-ketomonocarboxylic acid that triggers insulin release by acting upon receptor sites which differ from those occupied by amino acids. 4-Methyl-2-oxovaleric Acid is an analogue of Isoleucine.<br>References Panten, U. et al.: Naun.-Schmied. Arch. Pharmacol., 291, 405 (1975); Funk, M.A. et al.: J. Nutrit., 117, 1550 (1987);<br></p>

<p>Applications 3,3-Difluoroazetidine Hydrochloride is used in preparation of Dihydropyrimidine compounds as antiviral agents.<br>References Song, H., et al.:U.S. Pat. Appl. Publ., (2020);<br></p>

<p>Applications N-Succinyl-5-aminoimidazole-4-carboxamide Ribose 5’-Phosphate is a metabolite of Purine. Since adenosine is a potent inhibitor of neuronal function, depressing the release of several excitatory transmitters and causing direct hyperpolarization of neurons, it was possible that the symptoms seen in adenylosuccinate lyase (ASase) deficient patients could reflect an interference of succinylpurines with neurotransmission.<br>References Gollub, E.G., et al.: J. Bacteriol., 78, 320 (1959), Srivastava, P.C., et al.: J. Med. Chem., 17, 1207 (1974),<br></p>

<p>Applications An inhibitor of glucose synthesis.<br>References Martirosyan, A., et al.: Biochem. Pharmacol., 68, 1729 (2004),<br></p>

<p>Applications 3-Iodobenzyl Bromide is a reagant used in the investigation of thyreostats in bovine urine and thyroid glands.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Chiesa, L. M., et al.: Chromatographia, 79, 591-599 (2016);<br></p>

<p>Applications Diethylamine Hydrochloride is a secondary amine and a precursor of Atrazine (A794600). It is used as a reactant if the production of pesticides, dyes and pharmaceutical compounds.<br>References Raghuram, P. et al.: Chromatograph., 71, 963 (2010); Smith, D. &amp; Crowley, D.: FEMS Microbiol. Ecol., 58, 271 (2006); Asiri, A.: Dyes and Pigments., 42, 209 (1999); Rijhsinghani, K. et al.: Canc. Det. Prev., 5, 283 (1982)<br></p>

<p>Applications A naturally occurring nitrostable secondary amine found in tabacco smoke condensate.<br>References Singer, G.M. et al.: J. Agric. Food Chem. 24, 553(1976); Bush, L. P. et al.: Can. J. Plant Sci. 50, 289(1970).<br></p>

<p>Applications meso-Tetra (N-methyl-2-pyridyl) porphine tetrachloride is a synthetic porphyrin for research.<br></p>

<p>Applications N,N-Dimethylthioformamide<br></p>

<p>Applications Tris(2-​aminoethyl)​amine is a tetradentate chelating ligand and forms stable complexes with transition metals.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Xu, C., et al.: J. Mater. Chem. A, 3, 16229-16234 (2015); Sietzen, M., et al.: Organometallics, 34, 1118-1128 (2015);<br></p>

<p>Applications 2-Aminothiazole is a heterocyclic amine and is the beginning reagent for the synthesis of many pharmaceutical and agricultural related compounds.<br>References Gallardo-Godoy, A., et al.: J. Med. Chem., 54, 1010 (2011); Lai, H., et al.: Antiviral. Res., 97, 74 (2013); Yamamoto, K.N., et al.: Environ. Molec. Mutagen., 52, 547 (2011);<br></p>

<p>Stability Moisture Sensitive<br>Applications δ-Valerolactone is a compound commonly used to synthesize copolyesters by means of lipase-catalyzed ring opening polymerization.<br>References Faÿ, F., et al.: Eur. Polym. J., 43, 4800 (2007); Küllmer, K., et al.: Macromol. Rapid Comm., 19, 127 (1998)<br></p>

<p>Applications An intermediate in the preparation of Piperidinyloxy free radical derivatives.<br>References Irie, O., et al.: Bioorg. Med. Chem. Lett., 18, 5280 (2008),<br></p>

<p>Applications 4-(2-Amino-ethyl)-benzoic Acid is a useful reagent for the preparation of amino acid derivatives with anticancer activity.<br>References Kim, S., et al.: PCT Int. Appl. (2020), WO 2020204548 A1<br></p>

<p>Applications Indole-3-pyruvic Acid is a compound involved in the biosynthesis of Indole-3-acetic acid, a plant hormone which plays important roles in regulating growth and responses to environmental changes.<br>References Kong, W., et al.: Plant Cell Physiol, 56, 715-726 (2015)<br></p>