Building Blocks

<p>Applications 1-methyl-3-phenyl-1H-pyrazole is a useful research reagent for the synthesis of bioactive important small molecules.<br>References Blum, L. C., et al.: J. Chem. Inf. Model., 51, 3105 (2011); Koronatov, A. N., et al.: J. Org. Chem., 83, 210 (2018)<br></p>

<p>Applications 2-methylquinoline-4,6-diamine (cas# 5443-31-2) is a useful research chemical.<br></p>

<p>Applications Misonidazole can be used as a potential hypoxic cancer cell radiosensitizer and DNA binding and nicking agent. The metabolites of misonidazole can themselves be cytotoxic or they can increase the chemosensitivity and radiosensitivity of the target cells<br>References Bonnet, M., et al.: Bioorg. Med. Chem., 22, 2123 (2014); Edwards, D.I.: Comprehensive Med. Chem., 2, 725 (1990); Murata, R., et al.: Radiother. Oncol., 87, 331 (2008); Brown, J.M. The mechanisms of cytotoxicity and chemosensitization by misonidazole and other nitroimidazoles. Int.J.Radiat.Oncol.Biol.Phys. 8(3-4), 675-682 (1982).<br></p>

<p>Applications Naphthalene-1-d1 (CAS# 875-62-7) is a useful isotopically labeled research compound.<br></p>

<p>Applications Nonyl 4-Hydroxybenzoate-d4 is labelled Nonyl 4-Hydroxybenzoate which was used to prepare 4-[(aminosulfonyl)oxy] benzoic acid derivatives as potent inhibitors of the enzyme estrone sulfatase (ES). It was also used to synthesize sulfonylbenzoic acid esters as potential inhibitors of oestrone sulphatase with antitumor activities.<br>References Ahmed, S., et al.: Bioorg. Med. Chem. Lett., 12, 2391 (2002); Owen, C., et al.: J. Pharm. Pharmacol., 55, 85 (2002)<br></p>

<p>Applications Methyl 4-methoxypicolinate is a useful intermediate for the synthesis of substituted terpyridine ligands for use in protein purification.<br>References Lin, C., et al.: Tetrahedron, 70, 8520 (2014)<br></p>

<p>Applications Methylcyclohexane-d11 (ring-d11) (CAS# 352431-19-7) is a useful isotopically labeled research compound.<br></p>

<p>Applications Methylcyclopentane-d12 (CAS# 144120-51-4) is a useful isotopically labeled research compound.<br></p>

<p>Applications 1-(4-Methoxyphenyl)ethanol (cas# 3319-15-1) is a useful research chemical.<br></p>

<p>Applications N-Methylurea is used as a reagent in the synthesis of bis(aryl)(hydroxyalkyl)(methyl)glycoluril derivatives and is a potential byproduct of caffeine.<br>References Antonova, M.M., et al.: Chem. Heterocycl. Comp., 50, 503 (2014); Zarrelli, A., et al.: Sci. Total Environ., 470, 453 (2014)<br></p>

<p>Applications Methyl 5-cyano-2-fluorobenzoate<br></p>

<p>Applications trans-2-Methyl-cyclopropyl Boronic Acid Pinacol Ester can be synthesized from trans-1-Propen-1-ylboronic Acid (7547-97-9).<br></p>

<p>Applications 2-(Methoxy-d3)-3-(2-methylpropyl)pyrazine is an intermediate used in the preparation of 2-methoxy-3-alkylpyrazines and their deuterated isotopologues.<br>References Schmarr, H. G., et al.: J. Label. Compds and Radiopharm., 54, 438 (2011); Gerritsma, D. A., et al.: J. Label. Compds. Radiopharm., 46, 243 (2003)<br></p>

<p>Applications 2-Methoxy-d3-pyrazine (CAS# 32046-21-2) is a useful isotopically labeled research compound.<br></p>

<p>Applications Methyl 4-(trifluoromethyl)benzoate<br></p>

<p>Applications 4-(Methyl-d3-amino)butyric-2,2,3,3,4,4-d6 Acid HCl (CAS# 1219805-36-3) is a useful isotopically labeled research compound.<br></p>

<p>Applications 2-Methoxycarbonylphenylboronic acid<br></p>

<p>Applications (4-Methoxy-3,5-dimethylpyridin-2-yl)methanol (cas# 86604-78-6) is a useful research chemical.<br></p>

<p>Applications 2-Methylbenzothiazole-6-carboxylic Acid is a useful research chemical, a reagent for the synthetic studies on fungicidal agents.<br>References Saikachi, H., et al.: Yakugaku Zasshi, 78, 376 (1958)<br></p>

<p>Applications 1-(1-methyl-1H-1,2,3-triazol-5-yl)ethan-1-one (cas# 194209-18-2) is a useful research chemical.<br></p>

<p>Applications 3-Methoxy-2-nitrobenzoic acid<br></p>

<p>Applications 2-(1-Methyl-1H-pyrazol-4-yl)ethanamine (cas# 796845-58-4) is a useful research chemical in the development of DNA-compatible methodology for generating novel highly functionalized imidazoles.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Geigle, S. N., et al.: Org. Lett., 21, 9001 (2019)<br></p>

<p>Applications Methyl trans-Cinnamate-d5 (phenyl-d5) (CAS# 61764-82-7) is a useful isotopically labeled research compound.<br></p>

<p>Applications 1-(2-Methylpropyl)-4-piperidone had potential use in the manufacturing of medicament for promoting bone regrowth and repair.<br></p>

<p>Applications 2-(Methylsulfonyl)benzenemethanol is an intermediate used in the synthetic preparation of thiophene inhibitors of polo-like kinase.<br>References Emmitte, K.A., et al.: Bioorg. Med. Chem., 19, 1018 (2009);<br></p>

<p>Applications 4-Methyl-2-pentanol-1,1,1-d3 is a useful isotopically labeled compound of 4-Methyl-2-pentanol (M324750)<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>