Building Blocks

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

1-Acetylcyclopropane-1-carboxylic acid is a dicarboxylic acid that is produced by the alkylation of chloride with triethylbenzylammonium. It can be used to produce cyclopropanol, which can undergo an annulation reaction to form cyclopropylcarbinols. 1-Acetylcyclopropane-1-carboxylic acid has been shown to undergo rearrangement reactions in the presence of sodium hydroxide, and has been shown to be a good substrate for nucleophilic substitution reactions. This chemical also undergoes esterification with alcohols to form esters.

<p>Versatile small molecule scaffold</p>

<p>2-Bromo-3-methyl-5-nitrothiophene is an organic compound that reacts with nucleophiles, such as amines, to form adducts. It is also a ring-opening reaction of 2-nitrothiophene and oxidative deamination of aliphatic amines. This reactant is analogous to other compounds, such as 3-methylthiophene and 2,4,6-trinitrobenzene.</p>

<p>Bis(diisopropylamino)chlorophosphine is a phosphorylating agent that binds to the polymerase active site of the hepatitis C virus (HCV) NS5B protein. It is a promising anti-HCV drug candidate for the treatment of chronic hepatitis C infections. Bis(diisopropylamino)chlorophosphine has been shown to be effective in inhibiting HCV replication in vitro and in vivo, with no significant toxicity. Bis(diisopropylamino)chlorophosphine has also been shown to be an excellent probe for detecting HCV RNA in clinical samples by fluorescence microscopy. This compound has been successfully used in a phase I clinical trial and is currently undergoing phase II clinical development.</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

1-Benzoylpiperazine hydrochloride (1BP) is an antiviral prodrug that has been shown to inhibit HIV infection. It is a prodrug of benzylpiperazine, which inhibits viral replication by blocking the reverse transcriptase enzyme. 1BP is an amido derivative that is converted to benzylpiperazine in vivo, and then nitroreduced to form a reactive intermediate that binds irreversibly to the active site of the reverse transcriptase enzyme. This prevents the polymerization of viral DNA and formation of new viral particles. The drug also inhibits some strains of influenza A virus, herpes simplex virus type 2, and vaccinia virus. 1BP has antiviral activity against HIV-1, HIV-2, influenza A virus (strains H1N1 and H3N2), herpes simplex virus type 2, and vaccinia virus. It also has anti-inflammatory effects in vitro

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Ethyl 2-amino-2-methylbutanoate is a type of chemical compound that belongs to the group of organic compounds called esters. It has been shown to be a potential anti-cancer drug that inhibits DNA replication and induces apoptosis in cancer cells. Ethyl 2-amino-2-methylbutanoate has also been shown to have an effect on the histone lysine residues, which are important for cell proliferation and differentiation. Animal studies have suggested that this compound may also protect against breast cancer, with the ability to reduce tumor growth by inhibiting the production of estrogen receptors in mammary glands. The anticancer activity of Ethyl 2-amino-2-methylbutanoate is due to its ability to inhibit diltiazem hydrochloride, which is an enzyme involved in the synthesis of DNA and RNA.

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>2-Hydroxy-2-methyl-3-phenylpropanoic acid is a chlorinating agent that can be used as a cancer drug. It is one of the active substances in the plant didemnin, which has shown anticancer effects. 2-Hydroxy-2-methyl-3-phenylpropanoic acid reacts with oxindole to form 2,4,5,6,7 tetrahydrooxindole and 2,4,5,6 tetrahydrodideoxyoxindole. The chlorination reaction is catalyzed by corynebacterium glutamicum and produces epoxides. The epoxide ring opens under physiological conditions and reacts with hydroxyl groups on other molecules to form chlorohydrins or hydroxylamines.</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold