Building Blocks

4-Bromo-3-iodonitrobenzene is a pyrrole derivative that yields 4-bromo-3-iodobenzene upon treatment with palladium. It is a precursor to other products, such as 3-iodo-4-(pyrrolidinomethyl)benzoic acid and 4-(pyrrolidinomethyl)benzoic acid. This compound can be used in the synthesis of biomolecules, such as nucleosides, nucleotides, amino acids, peptides, and proteins. The synthesis of this compound involves deuterium exchange between the bromine and the hydrogen on the nitrogen atom. For example, if 4-bromo-3-iodonitrobenzene reacts with sodium methoxide in methanol it will produce 4-(methylamino)-3-(iodomethyl)aniline hydrochloride. The reaction yield of this

1-Cyclohexylpropyl carbamate is a diagnostic agent that can be used to measure inflammatory bowel disease. It is an analog of 1-cyclohexyl-2,2,2-trifluoroethyl carbamate. The compound is insoluble in water and must be reconstituted with a diluent prior to use. The particle size of the reconstituted compound can be adjusted by varying the concentration of the diluent. 1-Cyclohexylpropyl carbamate binds to herpes simplex virus type 2 (HSV-2) with high affinity and has been shown to inhibit HSV-2 replication in cell culture. Iontophoresis is a technique for delivering ionic molecules into tissue by means of an electric field. This technique has been shown to increase the concentration of 1-cyclohexylpropyl carbamate within cells infected with HSV-2.

Methyl 2,2-dimethyl-3-oxopropanoate is an enantioselective propionate with an asymmetric synthesis. The enantiomers of methyl 2,2-dimethyl-3-oxopropanoate are separated by the use of a chiral auxiliary. The enantioselective synthesis of propionates is achieved by crotylboration, a reaction that uses boron and crotyl alcohol as substrates. Methyl 2,2-dimethyl-3-oxopropanoate is an example of a polyketide synthesized via the polyketide pathway. This compound is used in the synthesis of halipeptin, which is an antibiotic that inhibits bacterial growth by inhibiting protein synthesis and cell division.

1-(4-Chlorophenyl)propan-1-ol is a ligand that binds to the active site of enzymes, such as chiral alcohol dehydrogenase and amino alcohol dehydrogenase. It was used to catalyze the synthesis of optically pure products in enantioselective reactions. 1-(4-Chlorophenyl)propan-1-ol has been shown to be an excellent precatalyst for asymmetric catalysis. It also reacts with amino alcohols to form optically pure products in an experiment involving the use of chiral azetidine.

2-(4-Methoxybenzyloxy)ethanol is a reversible and efficient catalyst for the dehydration of adenine. It is used in chemical synthesis to make 2,4-dibromoacetic acid. This compound has also been shown to be an effective dehydratase for clostridium.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

N-[4-Chloro-3-(trifluoromethyl)phenyl]-2,2-dimethylpropanamide is a white crystalline solid that belongs to the class of chains. This compound has hydrogen bonds and pivaloyl groups. It is also torsion and has a benzene ring. N-[4-Chloro-3-(trifluoromethyl)phenyl]-2,2-dimethylpropanamide is used in the synthesis of pharmaceuticals.

1-(2-Bromoethyl)naphthalene is a heterocyclic compound with two bromine atoms attached to the same carbon atom. It has two stereoisomers, one of which can be synthesized from phenacyl and the other from diketone. It is used in organic synthesis as a reactive intermediate for the alkylation of various substrates. The rate of reactivity is dependent on the electron donating ability of the substrate, with electron-donating groups resulting in faster reaction rates. This product has been shown to undergo enthalpic transfer reactions at room temperature, and chemoselective alkylation reactions at elevated temperatures.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

2-Hydroxyethane-1-sulfonamide is a potent antiviral agent that inhibits the virus from entering cells by binding to the fatty acid component of the viral envelope. It also has potent antitumor activity and has been shown to be effective against HIV infection. 2-Hydroxyethane-1-sulfonamide binds to mitochondrial matrix proteins, inhibiting fatty acid oxidation and glycogen synthase kinase 3 (GSK3) activation. This inhibition leads to the depletion of cellular energy stores, which eventually results in cell death. 2-Hydroxyethane-1-sulfonamide also inhibits ammonolysis reactions, which converts ammonium into ammonia, a process that is necessary for nitrogen fixation in plants and bacteria.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Quinoline-3,4-diamine is a heterocyclic compound with a nitrogen atom in the ring. It is classified as an aromatic compound and has many different substituents. The most common are the methyl group, ethyl group, and enamine. Quinoline-3,4-diamine is used in the synthesis of pyridine compounds such as carbonyl chlorides and hydroxyl amines. It also reacts with alkoxy groups to form esters. Quinoline-3,4-diamine has been shown to have antioxidant properties and may be useful for treating dementia.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold