Building Blocks

<p>Versatile small molecule scaffold</p>

<p>(2S,6S)-2,6-Dimethylmorpholine is an optically pure compound that can be used to optimize the epoxidase reaction. It belongs to the class of morpholines and has two enantiomers. The (2R,6R)-enantiomer is more active than the (2S,6S)-enantiomer in catalyzing the epoxidase reaction. The temperature optima for both enantiomers are different with the (2R,6R)-enantiomer having a higher optimal temperature than the (2S,6S) enantiomer. This compound can be used as a chiral auxiliary to separate racemic mixtures by focusing on one enantiomer at a time. It can also be used as an analytical method for determining plate number and plate height.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>4-Hydroxy-5-methoxy-2-nitrobenzaldehyde (4HMN) is a proton donor that can be used as a crosslinking agent. It is an acidic compound that binds to the substrate, usually via hydrogen bonds. 4HMN has been shown to have good binding affinity for tumour cell lines and can be used as a crosslinking agent in bioconjugation reactions. It is also a reversible chemical reaction, which means it can be hydrolyzed under certain conditions. 4HMN has been shown to be capable of enhancing the rate of enzymatic reactions by acting as a cofactor or coenzyme, such as degradable enzymes and enzymes with low turnover rates. The kinetic process of these reactions are measured by fluorescence techniques and gel permeation chromatography.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-Oxohexanoic acid (2-OHBA) is a fatty acid that is synthesized from the amino acids lysine and methionine. It is involved in mitochondrial metabolism and has been found to be necessary for spermatozoa motility. 2-OHBA has been shown to inhibit the activity of glutamate dehydrogenase, an enzyme that catalyzes the conversion of glutamate to α-ketoglutarate, which is required for energy production. This inhibition leads to a decrease in ATP levels, which may cause a variety of symptoms, including fatigue and weight loss. Furthermore, 2-OHBA inhibits protein synthesis by blocking the incorporation of amino acids into proteins. The inhibition of this process can lead to high ammonia levels in the blood and accumulation of other nitrogenous wastes in tissues such as liver or muscle tissue. Analysis of urine samples has shown that 2-OHBA is excreted unchanged in urine.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2,2-Dimethyl-1,3-dioxan-5-ol is a chemical compound that has been shown to have catalytic properties. It has also been used as an additive in organic synthesis reactions to activate carboxylic acids. 2,2-Dimethyl-1,3-dioxan-5-ol is an oxygenated compound that can be synthesized by the reaction of pyridine and formaldehyde. This substance can be used in acidic conditions and must be activated by solketal or dioxane before use. The physical properties of this chemical are shown using FTIR spectroscopy on corncob samples and physicochemical parameters were determined using standard techniques.</p>

<p>1,9-Nonanediol is a chemical substance that has been synthesized with the use of a constant pressure process. It is an asymmetric synthesis with light exposure. The molecule has been characterized by chromatographic methods and has the molecular formula CH3(CH2)9O. 1,9-Nonanediol is a dodecanedioic acid and an aliphatic hydrocarbon. It exists in two forms: one hydroxyl group and one hydrogen bond, which are both involved in the dehydration process. This substance does not have any chloride or magnetic resonance spectroscopy properties because it does not contain any chlorine atoms or hydrogen atoms.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3,6-Dichlorobenzene-1,2-diol is a conjugate acid of benzene. It has two dimensions in the plane of the molecule and three dimensions in space. The molecule is composed of six carbon atoms, six hydrogen atoms, and one chlorine atom. 3,6-Dichlorobenzene-1,2-diol has a centroid at the center of the molecule that is surrounded by a ring of four hydrogen atoms. The hydrogen-bonded molecules stack on top of each other to form a hexagonal shape. 3,6-Dichlorobenzene-1,2-diol forms hydrogen bonds with other molecules through its lone pairs of electrons on both oxygen atoms as well as through its pi electron system.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>The chemical is a palladium-based complex that inhibits the activity of α4β7 integrin. It has been shown to be effective in prophylaxis and treatment of inflammatory diseases, such as autoimmune diseases, and other conditions, such as congenital disorders. The compound has been shown to inhibit the growth of plants by causing phytotoxic effects.</p>

<p>Versatile small molecule scaffold</p>

<p>N,N-bis(Hydroxyethyl)-2-aminoethanesulfonic acid sodium salt is a cross-linking agent for polymers. It has been shown to react with dimethylol propionic acid to form a hydroxyl group and a carboxylate. This reaction yields the product of bis(hydroxyethyl) aminosulfonic acid sodium salt. N,N-bis(Hydroxyethyl)-2-aminoethanesulfonic acid sodium salt can be used as a cross-linking agent in the manufacture of biodegradable polymers that are environmentally friendly and biocompatible. The viscosity of the reaction solution increases with an increase in temperature, which is due to the hydrophobic interaction between molecules.</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>1-chloro-4-fluoroisoquinoline is a chlorinating agent that has been used as a synthetic method for the synthesis of oxychloride. It is typically used in the presence of palladium catalyst, in the presence of phosphorus and under reductive conditions. The chlorination reaction is initiated by addition of hydrochloric acid or phosphorous oxychloride. The 1-hydroxyisoquinoline reacts with phosphorus to form a chloroformate, which reacts with fluorine gas to produce an intermediate chlorofluorinate. This intermediate then reacts with chlorine gas in the presence of palladium catalyst to generate the desired product, 1-chloro-4-fluoroisoquinoline.</p>

<p>Versatile small molecule scaffold</p>

<p>5-Oxotetrahydrofuran-2-carboxylic acid is a solid phase extraction compound that can be used to extract and purify compounds from biological samples. It is synthesized by an asymmetric synthesis of the acetate ester of 5-hydroxytetrahydrofuran-2-carboxylic acid, which is then hydrolyzed to give the desired product. 5-Oxotetrahydrofuran-2-carboxylic acid has been used in cell culture studies as a diagnostic agent for cancer cells. The reactive nature of this molecule allows it to react with chloride ions and fatty acids, which leads to the death of cancer cells.</p>

<p>Versatile small molecule scaffold</p>

<p>4-Iodo-1-methyl-1H-pyrazole-5-carbonitrile is a tetrazole molecule that has been shown to have potent and selective inhibitory activity against human PCSK9. This compound binds to the catalytic site of PCSK9 and prevents the formation of an active enzyme, therefore inhibiting the production of LDL cholesterol. 4-Iodo-1-methyl-1H-pyrazole-5-carbonitrile is a prodrug that is metabolized by acetaldehyde dehydrogenase to form an active inhibitor. The reaction proceeds in a chiral and enantioselective manner, which allows for the synthesis of racemic mixtures of this drug.</p>

<p>Versatile small molecule scaffold</p>

<p>Boc-His(Trt)-OH is a chemical compound that has been used in the laboratory to study uptake and binding of compounds. It is stable in complex with albumin, which has led to its use as a model system for studying hepatic steatosis. This chemical can be synthesized by solid-phase synthesis with trifluoroacetic acid and polypeptide synthesis. FT-IR spectroscopy has been used to characterize Boc-His(Trt)-OH, revealing its chemical diversity.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>(S)-2-Methylpiperidine hydrochloride is a synthetic reagent that can be used in asymmetric synthesis. It is a homochiral amide that can be used as a reagent for the efficient preparation of β-unsaturated piperidines. (S)-2-Methylpiperidine hydrochloride can be synthesized from a Grignard reaction with an aldehyde, which is an important chemical reaction in organic chemistry.</p>

<p>Versatile small molecule scaffold</p>

<p>(R)-(-)-3-Amino-3-phenylpropionic acid is a hydrogenated, stereoselective β-amino acid that is involved in the biosynthesis of animal health. The enzyme acylase catalyzes this reaction by binding with chiral pyridoxal phosphate to form an acylation product. The stereospecificity of the reaction is determined by whether the enzyme has a preference for L or D amino acids. Acylases are found in organisms such as mammals and bacteria.</p>

<p>Versatile small molecule scaffold</p>

<p>Trans-3-(Benzyloxy)cyclobutanol is a radiolabeled compound that is used as a model system for understanding the metabolism of drugs in humans. It has been shown to be metabolized by the liver to produce metabolites that are excreted in urine. Trans-3-(Benzyloxy)cyclobutanol has also been shown to have tumor cell line stability, which may be due to its ability to inhibit DNA synthesis and protein synthesis in vitro and reduce tumor cells in vivo. Trans-3-(Benzyloxy)cyclobutanol has been shown to have no effect on normal rat plasma and lung carcinoma cells, but does affect prosthetic group activity.</p>

<p>5-Amino-3-methylisothiazole HCl is a pyridine-5-carboxylic acid that inhibits bacterial growth by binding to the 50S ribosomal subunit. It has been shown to inhibit the growth of both aeruginosa and nalidixic acid resistant strains of S. aureus, P. aeruginosa, and P. mirabilis in vitro. 5-Amino-3-methylisothiazole HCl has also been shown to be active against E. coli, quinolone resistant strains of Proteus mirabilis, and methicillin resistant strains of Staphylococcus aureus in vitro.</p>

<p>MW 20,000 - 30,000</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold