Building Blocks

<p>Versatile small molecule scaffold</p>

<p>4-Chloro-2-methyl-5-nitroaniline is an organic compound with the chemical formula C6H4ClNO2. It is a nitro derivative of aniline. 4-Chloro-2-methyl-5-nitroaniline is a white solid that is soluble in water, alcohols, and ethers. It has a melting point around 206 °C and decomposes at temperatures over 350 °C. This compound can be obtained by reacting hydroxylamine with nitrous acid and chlorinating 2,5-dimethylaniline. The sequence of reactions can be summarized as follows: hydroxy group to nitro group, nitro group to methyl group, methyl group to acetyl or acetylamino, acetyl or acetylamino to acetylation or methylation, transformation from hydroxyl group to amino group and esterification from acid hydrazide to acid group.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>The synthesis of (2-bromophenyl)(phenyl)methanol is accomplished by the reaction of an aldehyde with bromine followed by an alkylation with magnesium. The product is obtained as a racemic mixture of enantiomers with a chiral center, which can be resolved by fractional crystallization or other separation methods. This method has been shown to be efficient for the synthesis of alcohols and carbinols, and stereogenic reactions.</p>

<p>Versatile small molecule scaffold</p>

<p>2-Amino-4H,5H-naphtho[2,1-b]thiophene-1-carbonitrile is a dihydronaphthalene compound that has been shown to be active against influenza viruses. It inhibits the virus by binding to the pyrimidine ring of the virus's RNA polymerase. This inhibits viral replication and reduces plaque formation. 2-Amino-4H,5H-naphtho[2,1-b]thiophene-1-carbonitrile has antiviral activity against influenza A and is effective in inhibiting h5n1 virus replication.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>1,4-Dimethyl 2-hydroxy-2-methylbutanedioate is an allylating agent that modifies the amino acid lysine residues in proteins. It has been shown to be effective in the treatment of skin lesions caused by Staphylococcus aureus and other bacteria because it inhibits bacterial growth through an antimicrobial effect. 1,4-Dimethyl 2-hydroxy-2-methylbutanedioate also has been used as a precursor for the synthesis of vitamin D3. This compound is metabolized in mammalian cells to form cysteamine, which is further converted to S-(1,4-dimethylpentadienoyl)cysteamine (DMPE). The resulting product can be used as a functional group on collagen or malic acid. 1,4-Dimethyl 2-hydroxy-2-methylbutanedioate also is used for modifications of mucocutaneous tissues such as skin and oral muc</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3-[(2-Methyl-2-propen-1-yl)thio]-5H-1,2,4-triazino[5,6-b]indole is a recombinant protein that binds to the ribosomal protein L11. It has been shown to inhibit the biosynthesis of the bacterial cell wall and therefore inhibit replication of the bacterial genome. 3-[(2-Methyl-2-propen-1-yl)thio]-5H-1,2,4-triazino[5,6-b]indole also inhibits the synthesis of proteins essential for cell division. This compound has been shown to bind to ribosomes in both prokaryotic and eukaryotic cells. It may have potential as an inhibitor of cancerous cells because it inhibits protein synthesis in mammalian cells.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3-Chloro-1,2,4-benzotriazine is an organic compound that is used as an anti-cancer agent. It is a cytotoxin that inhibits the growth of cells by binding to DNA. The Suzuki reaction was used to synthesize this compound in high yields. 3-Chloro-1,2,4-benzotriazine has potential anti-cancer activity and can be used in conjunction with other cytotoxic agents to treat cancer. This drug has been shown to have cytotoxic effects on tumor cells by inhibiting DNA synthesis and cell division.</p>

<p>Versatile small molecule scaffold</p>

<p>Thienopyridine analogs are a class of chemical compounds that function as agonists of the receptor α. These compounds have been shown to inhibit fatty acid oxidation and ATP production in rat liver cells, which may be due to their ability to activate AMP-activated protein kinase (AMPK). Thienopyridine analogs are being investigated for use as anti-inflammatory agents and cancer treatments.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Please enquire for more information about Diisopropylphosphine, 10wt.% in hexane including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Versatile small molecule scaffold</p>

<p>2-Bromo-3,3,3-trifluoro-1-propene is a chemical compound that has been synthesized in an asymmetric reaction. The reactant is bromopropane and the product is 2,2,2-trifluoropropene. The methylene group on the propene molecule is activated by the nucleophilic attack of a fluoride ion from hydrogen fluoride to form a cavity with a highly strained bond. The kinetic study of this reaction revealed that the activation energy for the reaction is 42 kJ/mol. Palladium-catalyzed coupling reactions are catalyzed by palladium and require nonpolar solvents such as toluene or dichloromethane. This type of reaction has been shown to be exothermic with an isolated yield of 1%.</p>

<p>Versatile small molecule scaffold</p>