Building Blocks

<p>Versatile small molecule scaffold</p>

<p>1,4-Dimethyl 2-hydroxy-2-methylbutanedioate is an allylating agent that modifies the amino acid lysine residues in proteins. It has been shown to be effective in the treatment of skin lesions caused by Staphylococcus aureus and other bacteria because it inhibits bacterial growth through an antimicrobial effect. 1,4-Dimethyl 2-hydroxy-2-methylbutanedioate also has been used as a precursor for the synthesis of vitamin D3. This compound is metabolized in mammalian cells to form cysteamine, which is further converted to S-(1,4-dimethylpentadienoyl)cysteamine (DMPE). The resulting product can be used as a functional group on collagen or malic acid. 1,4-Dimethyl 2-hydroxy-2-methylbutanedioate also is used for modifications of mucocutaneous tissues such as skin and oral muc</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>The synthesis of (2-bromophenyl)(phenyl)methanol is accomplished by the reaction of an aldehyde with bromine followed by an alkylation with magnesium. The product is obtained as a racemic mixture of enantiomers with a chiral center, which can be resolved by fractional crystallization or other separation methods. This method has been shown to be efficient for the synthesis of alcohols and carbinols, and stereogenic reactions.</p>

<p>Versatile small molecule scaffold</p>

<p>4-Chloro-2-methyl-5-nitroaniline is an organic compound with the chemical formula C6H4ClNO2. It is a nitro derivative of aniline. 4-Chloro-2-methyl-5-nitroaniline is a white solid that is soluble in water, alcohols, and ethers. It has a melting point around 206 °C and decomposes at temperatures over 350 °C. This compound can be obtained by reacting hydroxylamine with nitrous acid and chlorinating 2,5-dimethylaniline. The sequence of reactions can be summarized as follows: hydroxy group to nitro group, nitro group to methyl group, methyl group to acetyl or acetylamino, acetyl or acetylamino to acetylation or methylation, transformation from hydroxyl group to amino group and esterification from acid hydrazide to acid group.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>1-(4-Methylphenyl)-3-(prop-2-yn-1-yl)urea is a fluorescent derivative that can be detected with certain techniques. It has been used to detect phosphatases in cervical cancer cells and tumor cells. This compound is a ligand for the surface antigen of placental alkaline phosphatase (PLAP). It can also bind to other organic ligands, such as recombinant human erythropoietin (EPO), which may be useful for redirecting the action of this protein. 1-(4-Methylphenyl)-3-(prop-2-yn-1-yl)urea is an organic bispecific molecule that binds to two receptors, one on tumor cells and one on normal cells. This binding leads to cell death by apoptosis through the release of cytochrome c from mitochondria.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Flindersia laevicarpa is a small tree native to Australia. The leaves of the tree are used for medicinal purposes and contain 1,5-diphenylpentan-3-ol. Flindersia laevicarpa has been shown to have anti-inflammatory and antioxidant properties, as well as an ability to inhibit platelet aggregation.</p>

<p>Ethyl 5-oxo-3-thioxo-2H-1,2,4-triazine-6-carboxylate is an acid ethyl ester of the triazine compound ethyl 3,5,6,7,8,-tetrahydro-2H-[1]benzothiopyran-2,4(3H)-dione. It has been shown to inhibit bacterial growth by binding to the enzyme ribonucleotide reductase.</p>

<p>Versatile small molecule scaffold</p>

<p>2-Bromo-3,3,3-trifluoro-1-propene is a chemical compound that has been synthesized in an asymmetric reaction. The reactant is bromopropane and the product is 2,2,2-trifluoropropene. The methylene group on the propene molecule is activated by the nucleophilic attack of a fluoride ion from hydrogen fluoride to form a cavity with a highly strained bond. The kinetic study of this reaction revealed that the activation energy for the reaction is 42 kJ/mol. Palladium-catalyzed coupling reactions are catalyzed by palladium and require nonpolar solvents such as toluene or dichloromethane. This type of reaction has been shown to be exothermic with an isolated yield of 1%.</p>

<p>Versatile small molecule scaffold</p>