Building Blocks

Stability Hygroscopic
Applications 4-Phenolsulfonic Acid Sodium Salt Dihydrate preparation of N-pyrazolylbenzenesulfonylamide derivatives as activators of PPARs
References Vedananda, T., et al.: PCT Int. Appl., 61 (2005)

Applications 10H-Phenothiazine 5-Oxide is a by-product in the synthesis of Phenothiazine S,S-Dioxide (P297600). Phenothiazine S,S-Dioxide is a derivative of Phenothiazine (P318040), a key component of antipsychotic and antihistaminic drugs.
References Bansode, T., et al.: Eur. J. Med. Chem., 44, 5094 (2009); Baell, J., et al.: J. Med. Chem., 53, 2719 (2010); Howard, P., et al.: Environ. Sci. Technol., 44, 2277 (2010); Koren, J., et al.: J. Biol. Chem., 285, 2498 (2010); Amobi, N., et al.: Eur. J. Pharmacol., 627, 285 (2010)

Applications D-Phenylalanine, the stereoisomer of L-Phenylalanine (P319415) has been used in the synthesis of Schaeffer’s acid analogues as important structures in tuberculostatic design. They exhibit the ability to inhibit Mycobacterium tuberculosis type II dehydroquinase.
References Schmidt, M. et al.: ChemMedChem., 8, 54 (2013);

Impurity Aspartame EP Impurity C
Applications L-Phenylalanine (Aspartame EP Impurity C) is an essential amino acid. L-Phenylalanine is biologically converted into L-tyrosine, another one of the DNA-encoded amino acids, which in turn is converted to L-DOPA and further converted into dopamine, norepinephrine, and epinephrine. L-Phenylalanine is produced for medical, feed, and nutritional applications such as in the preparation of Aspartame. Neuroprotective product.
References Hollunger, G. et al.: Acta Pharmacol. Toxicol., 34, 391 (1974); Bagchi, S.P. et al.: Biochem. Pharmacol., 26, 900 (1977);

Applications Phenylboronic Acid is a compound used in organic synthesis of various pharmaceutical goods.
References Ainley, A.D., et al.: J. Chem. Soc., 2171 (1930);

Applications Phenyl chloroformate is a corrosive liquid that is used to synthesize Urazole, a five membered heterocyclic compound that reacts with aldoses to form α and β pyranosides and furanosides. Phenyl chloroformate is also used as a reagent to prepare Sorafenib (S676850), a multikinase inhibitor that targets the tumour and tumour vasculature in patients with melanoma.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Boettecher, B. & Meister, A.: Anal. Biochem., 138, 449 (1984); Chai, W., et al.: Tetrahedron Lett., 53, 3514 (20112); Eisen, T., et al.: Brit. J. Cancer, 95, 581 (2006); Kolb, V., et al.: J. Mol. Evol., 38, 549 (1994); Llovet, J., et al.: Engl. J. Med., 359, 378 (2008)

Applications L-Phenylephrine (cas# 59-42-7) is a useful research chemical.

Applications An intermediate in the manufacturing of pressor amines. The sulfate salt is used as topical vasoconstrictor.
References Zhang, L., et al.: Biochem. J., 340, 255 (1999), Miyazaki, M., et al.: J. Biol. Chem., 278, 33904 (2003), Li, C., et al.: Bioorg. Med. Chem. Lett., 19, 5214 (2009),

Applications 1-phenyl-1,2,3,4-tetrahydronaphthalene (cas# 3018-20-0) is a useful research chemical.

Applications A chiral arylalkylamine used as organocatalysts. Used in the synthesis and chiral recognition properties of novel fluorescent chemosensors for amino acid.
References Kristensen, T. E. et al.: Eur. J. Org. Chem., 30, 5185 (2009); Liu, W. et al.: You. Xua., 26, 518 (2006);

Applications Phenprocoumon is known for being an oral anti-coagulant.
References Kohl, C. et al.: Drug. Metab. Disp., 28, 161 (2000);

Applications An aryl hydrazine used in the preparation of various dyes and pharmaceutical compounds. It is used in the investigation of oligosaccharides as well as the structure of photosystem II.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Lattova, E. et al.: Meth. Mol. Biol., 534, 65 (2009); Anderson, L.B. et al.: J. Biol. Chem., 275, 4920 (2000);

Applications 2-Phenylacetimidamide hydrochloride (cas# 2498-46-6) is a useful research chemical.

Applications 1-(Phenylmethyl)-4-piperidinamine is used in the preparation of 4-substituted coumarins as novel acetylcholinesterase inhibitors used in the treatment and various therapeutic approaches to Alzheimer’s disease. It is also used in the synthesis of nicotinamide derivatives as anti-angiogenic agents.
References Razavi, S. et al.: Eur. J. Med. Chem., 64, 252 (2013); Choi, H. et al.: Bioorg. Med. Chem. Lett., 23, 2083 (2013);

Stability Hygroscopic
Applications 1-Phenylpiperazine was tested for its activity as a topical glaucoma agent.
References Blevins, W., et al.: J. Bacteriol., 112, 513 (1972), Cohen, M., et al.: J. Pharmacol. Exp. Ther., 223, 110 (1982), Parshikov, I., et al.: Appl. Microbiol. Biotechnol., 56, 474 (2001),

Applications N-(Phenyl)-2-naphthylamine is a reagent in the preparation of unsymmetrical triaryldiamines as thermally stable hole transport layers for various organic LEDs.
References Koene, B. et al.: Chem. Mat., 10, 2235 (1998)

Applications 2-Phenylbenzothiazole is an organic compound that was detected in water and sediment from sedimentation ponds as a contaminant.
References Grung, M., et al.: Sci. Total Environ., 751, 141808 (2021)