Building Blocks

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

5-Cyano-1-methylbenzoimidazole is a pyridine that is used primarily in the synthesis of anticancer drugs. It has been shown to have significant cytotoxic effects on cancer cells and inhibit cell growth. 5-Cyano-1-methylbenzoimidazole is synthesized from 1,2,4-triazol and methyl benzoate.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

2,3,4,5-Tetrahydro-1,5-benzothiazepin-4-one is an organic compound that is used in the synthesis of pharmaceuticals. It is a ketone that has been shown to be active against some alkali metal ions such as potassium and sodium. 2,3,4,5-Tetrahydro-1,5-benzothiazepin-4-one reacts with an ethyl acetate solution of potassium carbonate to give a precipitate. The reaction proceeds through an acylation reaction between the ethyl acetate and potassium carbonate. This reaction is catalyzed by hydrogen bonds between 2,3,4,5-tetrahydro-1,5 benzothiazepin-4 one and the ethyl acetate molecule. This compound also reacts with esters to form ester derivatives. It has been shown to have an optically active form when dissolved in dieth

7-Chloro-6-nitroquinazolin-4(1H)-one is a manipulator that has been shown to be effective in the treatment of epidermal growth. The compound was found to be an efficient inhibitor of protein kinases and histone deacetylases, which are important for the regulation of cellular proliferation. 7-Chloro-6-nitroquinazolin-4(1H)-one is also a nucleophile that reacts with electrophiles such as organic peroxides and nitrosating agents. This reaction leads to the production of reactive oxygen species, which may contribute to its antitumor activity.

N-Methylthiophene-2-sulfonamide is an inhibitor of arylsulfonamides. It can be used to investigate the conformational and torsional effects of arylsulfonamides and their relationship to the inhibition of sulfonamide. N-Methylthiophene-2-sulfonamide has been shown to have good inhibitory activity against sulfonamide with conformation and torsional effects, which may be due to its ability to bind to the sulfanilamide in the active site. The computational results also show that this compound has potential for use as a drug candidate.

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Bromomethanesulfonamide is a synthetic drug that is used to treat acute lymphoblastic leukemia and hepatitis. It inhibits the activity of the enzyme ns5b polymerase, which is involved in viral replication. Bromomethanesulfonamide is also an NS5B polymerase inhibitor, which may be effective against some types of chronic hepatitis caused by a virus. This drug has been shown to inhibit serotonin synthesis in animals, but this effect has not been observed in humans. Bromomethanesulfonamide has also been used as a control agent for pharmaceutical preparations and carbonic anhydrase inhibitors for glaucoma treatment.</p>

6-Hydroxy-2H-benzo[b][1,4]oxazin-3(4H)-one is a dermatological active substance that is used in the treatment of skin diseases. It has been shown to be an immunosuppressant in animals and humans and can also be used in the treatment of respiratory disease. It has vasotropic properties and is an antiinflammatory agent. 6-Hydroxy-2H-benzo[b][1,4]oxazin-3(4H)-one is a topoisomerase II inhibitor that binds to DNA and prevents the unwinding of DNA strands by inhibiting the formation of topoisomerases II–DNA complexes. The compound binds to the C1 position on the cyclohexane ring, which contains both unsubstituted alkyl and unsubstituted aryl groups as well as elements such as silver halide.

5,6,7,8-Tetrahydro-8-quinolinecarbothioamide is a pyridine compound with the molecular formula C4H5N. It is an anti-ulcer agent that has been used in the synthesis of other organic compounds. This compound contains a pyridine ring with a nitrogen atom at position 8 that is substituted with a cyano group. It also contains two hydrocarbon rings and one nitro group at position 5. 5,6,7,8-Tetrahydro-8-quinolinecarbothioamide can be synthesized by reacting 2 equivalents of carbonyl fluoride with 1 equivalent of sodium nitrite in the presence of copper metal.

<p>Versatile small molecule scaffold</p>

2-(Aminomethylidene)-2,3-dihydro-1H-inden-1-one is a lipophilic drug that is used in pharmaceutical preparations. It is a non-irritating and non-sensitizing agent that does not cause any significant sensitization reactions. It is used as a diagnostic aid for the detection of fatty acid esters in tissue samples, an enhancement agent during cavity preparation, and as pharmaceutical dosage for treatment of depression. This compound has been shown to act as a transporter gene modulator and can be found in tissues such as the brain, heart, kidney, liver, spleen, adrenal gland and pancreas. 2-(Aminomethylidene)-2,3-dihydro-1H-inden-1-one may be conjugated with glutathione or sulfate and excreted into bile. Fatty acids are transported into cells by carriers