Building Blocks

Versatile small molecule scaffold

α-Vinylbenzyl alcohol is a chiral compound with a hydroxyl group. It is an allylation product of hydrochloric acid and allyl chloride. α-Vinylbenzyl alcohol has been shown to be effective against allergic reactions in human serum, which are caused by the release of histamine. This chemical compound also has nucleophilic attack capabilities that can produce reaction products such as malonic acid or allyl carbonate. The effective dose for this drug is not known, but it may be around 1mg/kg of body weight.

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>4-Isopropylphenyl)acetaldehyde is a phosphodiesterase inhibitor that has been shown to inhibit the activity of cyclic nucleotide phosphodiesterases. These enzymes have been implicated in the development of Alzheimer's disease and other neurological disorders. 4-Isopropylphenyl)acetaldehyde inhibits the formation rate of cAMP, which leads to downstream effects on neurotransmitter release, causing an increase in signaling from receptor cells and an increase in cytoarchitecture. The drug also inhibits phosphodiesterase activity in nasal tissue and parathyroid glands, leading to increased levels of intracellular cAMP. 4-Isopropylphenyl)acetaldehyde is only active against cyclic nucleotide phosphodiesterases that are sensitive to inhibition by this compound.</p>

<p>Azecane is a functional group that contains an hydroxyl (OH) and a lactam (-NH-C(=O)-). It is used in the synthesis of α-lactams, which are antibiotics. Azecane has been shown to be a potent inhibitor of cancer cells. It has also been shown to have strong inhibitory effects on bacteria, such as methicillin resistant Staphylococcus aureus and Mycobacterium tuberculosis. Azecane is synthesized through an asymmetric synthesis process involving silver ions and nitrogen atoms. This process produces two enantiomers, which can be distinguished by optical imaging techniques.</p>

Methyl phthaloyl chloride is a phenoxy compound that has been used as an inhibitor in the preparation of cyclic peptides. This compound has been shown to have anticancer and antiviral properties, and it also inhibits the growth of cancer cells by inhibiting cell-cycle progression. Methyl phthaloyl chloride is a nitro compound that can undergo nucleophilic attack by water molecules to produce an amide. The structural formula of this compound is shown below.

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>2-Cycloheptylacetic acid (2CHA) is a hydrochloride salt of 2-cycloheptylacetic acid. It has been shown to be a potent inhibitor of the GABA transaminase enzyme, which leads to GABA accumulation in the brain and thus an increase in GABAergic signalling. This inhibition leads to increased inhibitory neurotransmission and decreased excitatory neurotransmission in the brain. 2CHA has been validated with electrochemical impedance spectroscopy as a diagnostic tool for bowel disease, with potential applications for inflammatory bowel disease.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Ethyl sulfamate is a drug that has been developed as an agrochemical and as a potential anticancer agent. It is an aziridine-forming reagent that is used to convert epidermal growth factor (EGF) into EGF-2, which has been shown to have anticancer properties. The mechanism of action of ethyl sulfamate is not yet fully understood, but it appears to be related to its ability to inhibit the kinase activities of protein tyrosine kinases and protein serine/threonine kinases. In addition, ethyl sulfamate inhibits the activity of acid catalyst and enhances the activity of depression in rats. Ethyl sulfamate can also be used as a selective growth factor for erythrocyte progenitor cells in culture.</p>

Benzylsulfinic acid is a hydroxyl group containing compound. It is an antihypertensive agent and it has been shown to have antioxidant properties. Benzylsulfinic acid is photosensitive and should not be used in the presence of light. This compound has been shown to inhibit the production of tiglic acid, which is a component of bowel disease, in the small intestine. Benzylsulfinic acid can also be converted into other compounds that are involved in biochemical reactions, such as hydrochloric acid, a cationic surfactant, or methyl ethyl sulfate. This conversion process can lead to metabolic disorders, as well as hydrogen bond and methyl ethyl sulfonium ion formation.

<p>Versatile small molecule scaffold</p>