Building Blocks

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>4-IBP is a drug candidate for prostate cancer. It has been shown to inhibit tumor cell growth and induce autophagy, which is a process whereby cells can eliminate damaged proteins and organelles. 4-IBP also inhibits the uptake of glucosylceramide, which is required for the synthesis of complex lipids that are important in cellular signaling pathways. 4-IBP is able to bind with human protein and inhibit serotonin reuptake inhibitor. This drug also binds with receptors that are involved in the inhibition of prostate cancer cell proliferation.</p>

<p>3,5-Bis(trifluoromethyl)cinnamic acid is a hydrophobic molecule that can be encapsulated in nanocarriers and used for drug delivery. The encapsulation of hydrophobic molecules in nanocarriers can increase their solubility and stability. 3,5-Bis(trifluoromethyl)cinnamic acid has been shown to form micelles with ethylene oxide chains. Micelles are spherical structures formed by amphiphilic molecules that have both a hydrophobic and a hydrophilic end. This characteristic allows the micelles to self-assemble when they are mixed with water or other polar liquids such as oil. 3,5-Bis(trifluoromethyl)cinnamic acid is also an antagonist at the CXCR1 receptor, which is involved in inflammatory processes.</p>

<p>Benzyl 2-bromo-2,2-difluoroacetate (BBDFA) is a synthetic drug that is used as an inhibitor of human leukocyte elastase. It is used in diagnostic and industrial process to inhibit the proteolytic activity of leukocyte elastase. This compound has been shown to be effective in the treatment of degenerative diseases such as Alzheimer's disease and Parkinson's disease. The inhibition of leukocyte elastase by BBDFA may provide a therapeutic benefit by reducing the levels of extracellular matrix degradation products from tissue or organs. <br>Benzyl 2-bromo-2,2-difluoroacetate is synthesized by reacting cyclic acetal with bromine followed by reaction with difluoroacetic acid. The compound inhibits the enzyme proteolytic through binding to its active site, which blocks access to substrate peptides.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Methyl 2-isopropyloxazole-4-carboxylate is a pharmacokinetic enhancer used in cancer therapy. It is an estrogen metabolite that can be used to modulate the estrogen profile, lowering it by inhibiting the production of estrogen. Methyl 2-isopropyloxazole-4-carboxylate has been shown to increase the efficiency of ligands, which are drugs that bind to proteins and alter their function. This drug has also been shown to lower levels of estrogens and progesterone in monkeys. The correlation between serum estradiol levels and tumor growth has also been studied in these animals. Methyl 2-isopropyloxazole-4-carboxylate could potentially be used therapeutically against hormone receptor positive cancers such as breast cancer, prostate cancer, or ovarian cancer.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>