Building Blocks

<p>Iridium(III) bis-(2-phenylpyridine) (Ir{dFCF3ppy}2(bpy)) is a monomeric amido ligand that can be used in polymerization processes. It has an average molecular weight of 185.8 and a transition temperature of -55°C. Ir{dFCF3ppy}2(bpy) is soluble in organic solvents such as chloroform and acetone and will react with amines, anionic sites, and cycloalkyl groups to form polymers. The yields of the polymerization process are dependent on the starting materials used.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Cabozantinib is a small molecule that is the first to target VEGFR-2, which is a receptor tyrosine kinase involved in the development of fibrosis. Cabozantinib inhibits the activity of VEGFR-2 by binding to its ATP-binding site and blocking the phosphorylation of downstream signaling pathways. Cabozantinib has been shown to have antifibrotic properties in both preclinical and clinical models. The drug candidate has been shown to reduce kidney fibrosis in animal models. The standard dose for cabozantinib was found to be 5 mg/kg, with a maximum tolerated dose of 20 mg/kg. In vitro studies have indicated that cabozantinib binds with high affinity to the ATP-binding pocket of VEGFR-2, exhibiting competitive inhibition against other kinases such as PDGFR-beta and cKit, as well as diaryliodonium (a specific inhibitor). Caboz</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>4-(Isopropylamino)butanol is a colorless liquid with an alkaline reaction. It reacts easily with acids and is soluble in water. The boiling point of this substance is 242°C. In the presence of ammonium chloride, the solution becomes acidic. 4-(Isopropylamino)butanol is used as a solvent for paints, varnishes, and lacquers.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Tadalafil is a synthetic drug that is used as a treatment for erectile dysfunction. It works by inhibiting the PDE5 enzyme, which is responsible for breaking down cGMP. Tadalafil has been shown to be effective in the treatment of male erectile dysfunction and pulmonary hypertension, with few side effects. This drug is taken orally, with a meal or without one, and can be administered with or without food. To improve absorption, tadalafil should be taken at least 30 minutes before sexual activity. The dosage of tadalafil ranges from 2.5 to 20 mg, and it should not exceed 40 mg per day.</p>

<p>Please enquire for more information about 2,2,2-Trifluoroethanesulfinyl chloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>