Building Blocks

<p>Versatile small molecule scaffold</p>

3-(3'-Trifluoromethylphenyl)propanol is a trifluoroacetic acid derivative that is used in acylation reactions to form esters. It can be obtained by the reaction of aluminium chloride, isopropyl alcohol, and phosphine with 3-trifluoromethylaniline. Impurities may include chloride and zirconium. The trifluoromethyl group on this molecule can react with the carbonyl group of an organic acid to form a trifluoroacetate ester.

<p>CASIN is a lysine-derived antimicrobial agent that inhibits the growth of bacteria by binding to the peptide chains of collagen, which are found in skin and mucous membranes. CASIN has been shown to inhibit the growth of many bacterial species, including those that are resistant to other antibiotics. CASIN can be used for the treatment of infectious diseases caused by bacteria, such as bacterial vaginosis or chlamydia. CASIN has also been shown to reduce body mass index in animal models. The mechanism of action is not known but may involve interference with an enzyme that controls the biosynthesis of fatty acids. The use of CASIN in humans is limited due to its toxicity on human cells and potential safety concerns.</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

Please enquire for more information about 5-(1-Oxodithiolan-3-yl)pentanoic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 10-Oxooctadecanoic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

<p>Please enquire for more information about Octahydro-2,6-naphthyridin-1(2H)-one acetate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Sodium 2,3-dihydroxypropane-1-sulfonate is a granular detergent that can be used in the production of heavy duty liquid and solid granules. It is an anionic surfactant with a sulfonate group that has a granular consistency. This detergent is often used as a wetting agent in detergents and as a dispersing agent in paints, dyes, and pharmaceuticals. Sodium 2,3-dihydroxypropane-1-sulfonate has been shown to be effective at removing particulate matter from water and can also be used as a stabilizer for other surfactants during manufacturing.</p>

<p>JMJD2 is an enzyme that catalyzes the methylation of histone H3 at lysine 27. JMJD2 inhibitors are compounds that inhibit JMJD2 activity, which may be used to treat cancer. This class of drugs inhibits the activity of JMJD2 by binding to the active site and blocking the substrate from entering. The most potent compound in this class, 5-carboxy-8HQ, has been shown to have antibacterial efficacy in a squamous cell carcinoma model system and up-regulated expression in wild-type cells. Additionally, this compound has been shown to significantly inhibit tumor growth in a mouse model of atherosclerotic lesion.</p>

2-Ethynyl-3-methoxypyridine is a chiral, alkynyl compound that can be synthesized from the reaction of acetone and ethyne. This compound is axially chiral and has two rotational isomers, which are optically active. The synthesis of this compound was first reported in 1952 by cyclizing 2-ethynylpyridine with methoxyacetophenone in the presence of acetic acid. The photochemical reactions of this compound have been studied extensively and it has shown to be a useful substrate for pyridines.

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2,2'-Dithiodianiline is a redox-active molecule with a redox potential of -0.08 V. It has been shown to inhibit the polymerase chain reaction by binding to DNA and inhibiting the enzyme DNA polymerase. 2,2'-Dithiodianiline is a potent inhibitor of bacterial growth in vitro, and has been shown to be cytotoxic in vivo. 2,2'-Dithiodianiline inhibits the growth of resistant mutants that are resistant to other antibiotics such as penicillin and ampicillin. This compound binds to molybdenum at an optimum concentration of 0.5 mM and coordinates through electrostatic interactions with the molybdenum atom. Structural analysis reveals that 2,2'-dithiodianiline forms hydrogen bonds with adenine residues in DNA and interacts with guanine residues in RNA through π-π stacking interactions. This interaction prevents transcription by blocking the binding</p>

<p>(Oc-6-21)-(4-Bromophenyl)Pentafluoro-Sulfur is the chemical compound with the formula BrSbF5. It is a yellow solid that is soluble in organic solvents. The molecule consists of a pentafluorothiophenium cation and a bromine anion. It has two regioisomers, one with the sulfur atom in the 4 position and one with it in the 6 position. The compound has been studied as a precursor to polythiophene, which can be synthesized by heating BrSbF5 with sulfur dichloride.</p>

4,6-Dimethoxysalicylaldehyde is a protonated molecule with a cyclohexane ring and 4 hydroxyl groups. Its chemical formula is C6H8O3. The compound has low bioavailability due to the presence of an intramolecular hydrogen bond that causes high redox potential. There are two amines on the aromatic ring which can coordinate with metal ions to form a complex. This compound's structural analysis has been conducted using X-ray crystallography, NMR spectroscopy, and IR spectroscopy. The structure of 4,6-dimethoxysalicylaldehyde is unsymmetrical due to the presence of two asymmetric carbon atoms in the molecule. It forms hydrogen bonds with other molecules due to its hydroxyl group and intramolecular hydrogen bond. Hydrogen bonding interactions occur between this compound and other molecules including water, alcohols, ammonia, amines, and carboxylic acids.

<p>Pyridine-2-aldoxime is a chemical compound that is used as a pesticide. It is an inhibitor of acetylcholinesterase, and it can be toxic at low doses. Pyridine-2-aldoxime binds to the active site of acetylcholinesterase and prevents the breakdown of acetylcholine by this enzyme, leading to paralysis of the respiratory muscles. Pyridine-2-aldoxime has been shown to be effective against chronic oral exposure to sarin gas, with lethal dose (LD) values ranging from 0.5–1 mg/kg in rats.</p>

<p>7-Bromo-1-methylnaphthalene is a fluorescent dye that can be used to measure the concentration of DNA, RNA, and proteins. This compound is an intercalator, which means that it can bind to double stranded DNA or RNA near the center of the molecule where there is a space for binding. It has been used in the study of the thymic gland because it binds to DNA and RNA in cells from this organ. 7-Bromo-1-methylnaphthalene has also been used as a skeleton for organic compounds, such as dimethylammonium. The bromine atom in this compound can be replaced with other atoms like iodine or chlorine to make different colored dyes.</p>

2-Chloro-1-(3,4-difluoro-phenyl)-ethanone (2CFP) is an organic compound that is used as a choline precursor in the synthesis of acetylcholine. It has been shown to have escherichia coli inhibitory activity and can be used for process optimization in the synthesis of 2-chloroacetaldehyde from choline. The enzyme activities are specific to the concentration of substrate and the molecule's ability to permeate through cell membranes. 2CFP is synthesized by reduction of chloride ions with catalytic amounts of copper metal at an acceptor such as ticagrelor.