Acids and Synthetic Reagents

Stability Unstable in Solution, Air Sensitive
Applications 2-HYDROXYTHIOPHENOL (cas# 1121-24-0) is a useful research chemical.

Applications Tetramethylammonium Hydroxide is used to prepare a new family of silicate/aluminosilicate mesoporous molecular sieves.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Beck, J., et al.: J. Am. Chem. Soc., 114, 10834 (1992).

Applications NU6027 is a potent cyclin-dependent kinase (CDK) and Rad3-related kinase (ATR) inhibitor. NU6027 has been shown to inhibit tumor cell growth. NU6027 inhibits ATR, impairing G2/M arrest and homologous recombination thus increasing sensitivity to DNA-damaging agents and poly(ADP-ribose) polymerase (PARP) inhibitors
References Arris, C.E., et. al.: J. Med. Che., 43, 2797 (2000); Peasland, A., et. al.: Brit. J. Cancer, 105, 372 (2011)

Applications Silver Acetate is used as a reagent in chemical synthesis in reaction such as carbonylation of primary and secondary amines as well as in woodward cis-hydroxylation converting alkenes into cis-diols. Also used in gum, lonzenges and sprays that are targeted to assist people in quitting the habit of smoking since it produces a bad taste when combined with cigarettes.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Wright, L., et al.: J. Phys. Chem., 59, 1060 (1955); Woodward, R., et al.: J. Am. Chem. Soc., 80, 209 (1958); Lancaster, T., et al.: Cochrane DB Syst. Rev., 2, 191 (2000);

Applications Darodipine, is a calcium channel antagonist.
References Matucci, R., et al.: British J. Pharmacol., 122, 1353 (1997);

Applications 4-Bromobutyric Acid is used in the preparation of analgesic and anti-inflammatory agents as nitroalkyl ethers. It is also used in the synthesis of Autotaxin (ENPP2) inhibitors, used in tissue fibrosis regulation, cancer cell invasion and metastasis.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Anzini, M. et al.: J. Med. Chem., 56, 4821 (2013); Kawaguchi, M. et al.: ACS Chem. Biol. et al.: 8, 1713 (2013);

Applications Di-p-toluoyl-d-tartaric Acid Monohydrate is a useful intermediate in the preparation of chiral rivastigmine hydrogen tartrate.
References Feng, J., et al.; Nanfang Yike Daxue Xuebao, 27, 177 (2007)

Applications A peripheral µ-opioid receptor antagonist. Gastroprokinetic.
References Zimmerman, D.M., et al.: J. Med. Chem., 37, 2262 (1994), Liu, S.S., et al.: Clin. Pharmacol. Ther., 68, 66 (2000), Taguchi, A., et al.: N. Engl. J. Med., 345, 935 (2001),

Applications 2-Isobutyrylcyclohexanone (cas# 39207-65-3) is a useful research chemical.

Applications Tris(acetonitrile)cyclopentadienylruthenium(II) Hexafluorophosphate is a catalyst, and catalyzes the reaction of diynes with aldehydes and N,N-dimethylformamide and also catalyzes other organic reactions.
References Yamamoto, Y., et al.: J. Org. Chem., 82, 7964 (2017); Weber, S. M., org. lett., 19, 564 (2017); Wilkinson, L. A., et al.: Organometallics, 36, 4376 (2017)

Applications Mdivi-1 is an inhibitor of mitochondrial division DRP1 and Dynamin I.

Stability Moisture Sensitive
Applications Fluorescein Isothiocyanate is a fluorescent reagent with incompletely defined position of the NCS. Fluorescein Isothiocyanate is used in multifunctional uniform nanoparticles composed of a magnetite nanocrystal core and a mesoporous silica shell for magnetic resonance, fluorescence imaging. and drug delivery. Dyes and metabolites.
References Kim, J., et al.: Angew. Chem. Int. Ed., 47, 8438 (2008);

Applications 2-Bromobenzyl Alcohol acts as a reagent for the synthesis of alkoxy tetrasubstituted chiral amino acids via three-component reaction of (diazo)oxindoles, alcohols and benzhydrylimino ester involving enantioselective trapping of oxonium ylides by benzhydrylimino ester. Also acts as a reagent for the preparation of orally active and liver-targeted prodrug of 5-fluoro-2'-deoxyuridine for treatment of hepatocellular carcinoma.
References Jia, S., et al.: Chin. Chem. Lett., PagesAhead of Print (2016); Peng, Y., et al.: J. Med. Chem., 59, 3661 (2016)

Applications 4-Bromostyrene