Amines

<p>Fluorescamine (Ro 20-7234) non-fluorescent; reacts with amines, forming bright products; detects amines, peptides.</p>

<p>6-TAMRA (6-Carboxytetramethylrhodamine) serves as a popular fluorophore for the creation of bioconjugates, particularly in the synthesis of fluorescent</p>

<p>5-FAM SE, a single-isomer green fluorophore, labels peptides, proteins, nucleotides.</p>

<p>5(6)-TAMRA SE (5(6)-Carboxytetramethylrhodamine N-succinimidyl ester) is the amine-reactive, mixed isomer form of TAMRA.</p>

<p>5(6)-CFDA: cell-permeable, esterase-responsive viability probe; fluoresces upon activation, indicating enzymatic activity and membrane integrity.</p>

<p>BI-1467335 HCl(BI 1467335) is a selective, orally active inhibitor of semicarbazide-sensitive amine oxidase (SSAO) that helps improve chronic obstructive</p>

<p>Applications 2-Amino-2-phenylbutyric acid 96% (cas# 5438-07-3) is a useful research chemical.<br></p>

<p>Applications 1-Amino-2-propanol is a reagent used in the synthesis of protein kinase CK2 inhibitors used in the treatment of neoplasia and other infective diseases.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Pagano, M. et al.: J. Med. Chem., 47, 6239 (2004);<br></p>

<p>Applications 1-(Dimethylamino)-2-propanone is an intermediate in the synthesis of Amylocaine Hydrochloride which, is used mostly in spinal anesthesia.<br></p>

<p>Stability Hygroscopic<br>Applications 1-Adamantanamine Sulfate (cas# 31377-23-8) is a useful research chemical.<br></p>

<p>Applications E-3-(Tributylstannyl)-2-propen-1-amine (cas# 202115-92-2) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications Trimethyl-tetradecylammonium chloride,99% (cas# 4574-04-3) is a useful research chemical.<br></p>

<p>Applications 3-[(4-Bromophenyl)(methyl)amino]propanoic acid (cas# 231278-20-9) is a quinazoline derivative and an aryl iodide. 3-[(4-Bromophenyl)(methyl)amino]propanoic acid has also been used in the design, synthesis and biological evaluation of quinazoline-phosphoramidate mustard conjugates as anticancer drugs.<br>References Zhang, Y.; et al.: Bioorg. Med. Chem. Lett., 27, 1584 (2017); Lin, S.; Eur. J. Med. Chem., 127, 442 (2017).<br></p>

<p>Stability Hygroscopic, Light Sensitive<br>Applications 6-Hydroxydopamine is a selective catecholaminergic neurotoxin. Studies show that 6-Hydroxydopamine can be used to create an animal model of Parkinson's disease as it causes almost complete destruction of nigral dopaminergic neurons and their striatal terminals when injected into the substantia nigra of rats. 6-Hydroxydopamine induces apoptosis in PC12 cells.<br>References Soto-Otero, R. et al.: J. Neurochem., 74, 1605 (2000); Fujita, H. et al.: Brain Res., 1113, 10 (2006); Breese, G.R. et al.: 174, 313 (1970);<br></p>

<p>Stability Hygroscopic<br>Applications Used as an intermediate in the industrial preparation of non-ionic X-ray contrast agents such as Iohexol (I729500), Ioversol (I737000), Ioxilan (I737500), Iopamidol (I735600).<br>References Rongved, P., et al.: Carbohydrate Res., 297, 325 (1997),<br></p>

<p>Applications 5-Amino-2-chlorobenzotrifluoride is a compound useful in organic synthesis. It also performs a radioprotective activity against ionizing radiations.<br>References Blickenstaff, R. T., et al.: J. Pharm. Sci., 83, 219 (1994); Kumari, P., et al.: Org. Biomol. Chem., 16, 2049 (2018)<br></p>

<p>Applications Benzylamine Hydrochloride (cas# 3287-99-8) is a useful research chemical.<br></p>

<p>Applications 1,3-Diaminopropane is a common chemical reagent, used in the synthesis of 7-methoxytacrine-adamantylamine heterodimers as cholinesterase inhibitors applied in the treatment of Alzheimer’s disease. Also used in the synthesis of thrombosis inhibitors.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Spilovska, K. et al.: Molecules, 18, 2397 (2013); Smith, S. et al.: Blood, 120, 5103 (2012);<br></p>

<p>Applications 6-(6-(6-Aminohexanamido)hexanamido)hexanoic Acid is used in the making of a preconjugate which serves as immunoreactive conjugate useful as a developer antigen in a competitive inhibition immunoassay for the polymorphic analyte. Also used in the efficient synthesis of a heterobifunctional coupling agent.<br>References Oh, C. S., et al.: PCT Int. Appl. (1994), WO 9416330 A1 19940721; Reddy, R. E., et al.: Bioconjug. Chem., 16, 1323 (2005)<br></p>

<p>Stability Hygroscopic<br>Applications Neamine is normally found as a core structure of aminoglycoside antibiotics. It is used in the synthesis of disaccharide neamine derivatives as antibacterial agents.<br>References Kawaguchi, H., et al.: J. Antibiot., 25, 695 (1972), Fourmy, D., et al.: Science, 274, 1367 (1996), Riguet, E., et al.: J. Med. Chem., 47, 4806 (2004)<br></p>

<p>Applications PROP-2-EN-1-AMINE HCL (cas# 10017-11-5) is a useful research chemical.<br></p>

<p>Applications N-Ethyl-N-(2-hydroxyethyl)nitrosamine is a member of the nitrosamine class of carcinogens and induces renal cancer. It has been shown to induce tumors in the kidneys of rats and in the lungs of mice.<br>References Hiasa, Y., et al.: Cancer Lett, 145, 143-149 (1999)<br></p>

<p>Applications 6-Amino-5-1,3-dimethyl-5-(formamido)uracil is a substitued uracilic metabolite of methylxanthine and is also a metabolite of Theophylline (T343850). 6-Amino-5-1,3-dimethyl-5-(formamido)uracil has been used for the synthesis of 8-arylaminotheophyllines.<br>References Peri, G., et. al.: Toxicol. Lett., 18, 133 (1983); Celardo, A., et. al.: Eur. J. Drug Metab. Ph., 10, 279 (1985); Senga, K., et. al.: J. Heterocyclic Chem., 15, 641 (1978)<br></p>

<p>Stability Hygroscopic<br>Applications N-​(4-​Amino-​5-​oxoheptyl)​guanidine is a biosynthetic intermediate in the study of saxitoxin gene cluster in cyanobacteria.<br>References Kellmann, R., et al.: Appl. Environ. Microbiol., 74, 4044 (2008)<br></p>

<p>Applications N-(Benzyloxycarbonyl)ethanolamine is an intermediate used to prepare alkynylaryladenines as A2A adenosine receptor agonists and effects on hepatic glucose production. It is also used in the synthesis of functionalized N-arylaminoethyl amides as noncovalent inhibitors of cathepsin S.<br>References Harada, H., et al.: Bioorg. Med. Chem., 9, 2709 (2001); Tully, D., et al.: Bioorg. Med. Chem. Lett., 16, 5112 (2006)<br></p>

<p>Applications Ethylenediamine Dihydrochloride (cas# 333-18-6) is a useful research chemical.<br></p>

<p>Stability Stable at RT<br>Applications An intermediate used for the sythesis of xanthine derivatives.<br>References Daly, J.W., et al.: J. Med. Chem., 28, 487 (1985), Erickson, R.H., et al.: J. Med. Chem., 34, 3405 (1991),<br></p>

<p>Applications 2-[Methyl(phenylmethyl)amino]ethanol is used in the preparation of dihydropyrimidinones as sodium iodide symporter inhibitors used to regulate the accumulation of iodide in the thyroid gland. Also used in the synthesis of new class of pseudopeptides as potential inhibitors of β-sheet aggregation.<br>References Lacotte, P. et al.: ChemMedChem, 8, 104 (2013); Klein, J. et al.: Org. Lett., 14, 330 (2012);<br></p>

<p>Applications Ethylamine Solution is used as a reagent in the synthesis of a series of hexadentate ligands as potential antibacterial agents. Also used as a reagent in the synthesis of tetrahydrothiazolopyridine derivatives as potent smoothened antagonists.<br>References Zhang, M., et al.: Chem. Biol. Drug Des., 84, 659 (2014); Ma, H., et al.: Eur. J. Med. Chem., 89, 721 (2015)<br></p>

<p>Applications 4-Dimethylaminosulfotoluidide is an intermediate in the synthesis of Tolylfluanide (T536730), a polyvalent sulfamide fungicide that is closely related to dichlofluanide.<br>References Wainwright, A. et al.: Bright. Crop Prot. Conf. Pests Dis., 1, 275 (1996)<br></p>

<p>Applications N,N-Dimethyldodecylamine is used as a reagent in the synthesis of epoxy quaternary ammonium salt surfactants which exhibit potential antibacterial activity.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Liu, Y., et al.: J. Disper. Sci. Technol., 35, 1460 (2014)<br></p>

<p>Applications 5-Amino-1-pentanol is an aliphatic amino alcohol with potential plasma lipid-lowering properties. 5-Amino-1-pentanol and other amino alcohols are used as emulsifying agents in dry-cleaning soaps, wax removers, cosmetics, paints and insecticides.<br>References Bondesson, G. et al.: Acta Pharm. Suec., 11, 417 (1974); Scheers, E.M. et al.: ALTA Alt. Lab. Anim., 30,309 (2002);<br></p>

<p>Applications Cetyltrimethylammonium hydrogensulfate 99% (cas# 68214-07-3) is a useful research chemical.<br></p>

<p>Stability Light and Mositure Sensitive<br>Applications An amino substituted benzene used in the manufacture of dyes. Potential use in sensitive immunosensor for cancer biomarker.Environmental toxin on US EPA Toxic Release Inventory list (TRI) list.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Wu, Y. et al.: Anal. Bioanal. Chem., 400, 2141 (2011); Du, D. et al.: Anal. Chem., 82, 2989 (2010);<br></p>

<p>Applications 2-Amino-4,6,7,8-tetrahydro-5-(N-carbethoxy)thiazolo[5,4-d]azepine (cas# 887352-60-5) is a compound useful in organic synthesis.<br></p>

<p>Applications 4-Aminoantipyrine (cas# CAS:83-07-8) is a useful research chemical.<br></p>

<p>Impurity Mesalazine EP Impurity C<br>Applications 2-Aminophenol is an isomer of 4-Aminophenol (A618920) and is used as a reagent for the synthesis of heterocyclic compounds and dyes.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Pan, E., et al.: Chem. Sci., 4, 482 (2013); Meek, A.R., et al.: Can. J. Chem., 90, 865 (2012); Kiorpelidous, E., et al.: Chem. Res. Toxicol., 25, 2054 (2012);<br></p>

<p>Applications 2-(Acetylamino)-N-(phenylmethyl)propanamide, has shown to have anticonvulsant activity in vitro. Likely an impurity in the medication Lacosamide, (L098500).<br>References Martinez, J C. et al: MATCH, Vol. 67, issue 3, P: 745-758 (2012);<br></p>

<p>Applications Ethanolamine is used in the preparation of various pharmaceutical compounds and inhibitors. Substituted carboxamides are synthesized using Ethanolamine that show potent antitumor activity. Also used in the synthesis of aminoquinolones which display anti-plasmodial activity.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Lombardo, L. et al.: J. Med. Chem., 47, 6658 (2004); Egan, T.: J. Med. Chem., 43, 283 (2000);<br></p>

<p>Applications 3,4'-Diaminodiphenyl Ether, can be used for the synthesis of asymmetric soluble polyimides. It can also be used as a spacer in the preparation of glycine-based molecular tongs as inhibitors of β-amyloid peptide Aβ1-40 aggregation in vitro.<br>References Zhao, T., et al.: Suliao Gongye, 39, 20 (2011); Cellamare, S., et al.: Bioorg. Med. Chem., 16, 4810 (2008);<br></p>

<p>Applications 1,3,5-Benzenetriamine could have cosmetic applications. It could be used for colouring hair with nitrile-containing dyes.<br>References Suenger, G., et al.: PCT Int. Appl. (2005), WO 2005120445 A2<br></p>

<p>Applications 2-aminobenzene-1,4-disulfonic acid (cas# 98-44-2) is a useful research chemical.<br></p>

<p>Applications 2-​[(2-​Hydroxyethyl)​octadecylamino]​ethyl ester octadecanoic acid is used as a modifier to Polymer films of LDPE and ethylene-​vinyl acetate copolymers (EVA) to enhance antifog properties.<br>References Irusta, L., et al.: J. Appl. Polym. Sci., 111, 2299-2307 (2009);<br></p>

<p>Applications 1-Propylamine is used in the synthesis of pyrimidine derivatives as novel and highly potent PDE4 inhibitors. Also used in the preparation of fluorenone analogs with DNA topisomerase I inhibitors.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Goto, T. et al.: Bioorg. Med. Chem., 21, 7025 (2013); Lee, C. et al.: Bioorg. Med. Chem. 21, 7125, (2013);<br></p>

<p>Applications 2,4-DIAMINOPTERIDINE-6-CARBOXYLIC ACID (cas# 716-74-5) is a useful research chemical.<br></p>

<p>Applications N-(2-(2,4,6-TRICHLOROPHENOXY)ETHYL)PROPAN-1-AMINE (cas# 67747-01-7) is a useful research chemical.<br></p>

<p>Applications N,N-Dimethyltetradecylamine (cas# 112-75-4) is a compound useful in organic synthesis.<br></p>

<p>Stability Hygroscopic<br>Applications N-[4-[(4-Hydroxyphenyl)amino]phenyl]acetamide is used in the synthesis of lithographic plates.<br></p>

<p>Applications N,N-Dimethylhexadecylamine is used in the synthesis of 3-(N,N-Dimethylpalmitylammonio)propanesulfonate (D461825), a zwitterionic surfactant used in the preparation of a highly efficient adsorbent for herbicides, DHAPS-Mt.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Gu, Z., et. al.: Ind. Eng. Chem. Res., 54, 4947 (2015)<br></p>

<p>Stability Hygroscopic<br>Applications N-​Ethyl-​α-​methyl-​3-​(trifluoromethyl)​-benzeneethanamine hydrochloride has been used in case studies for the study of impulsivity, motor skills, and anxiogenic effects in the neuroscience community.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Whitney, K.N., et al.: Exp. Clin. Psychopharm., 21, 345-54 (2013); Arrant, A.E., et al.: Neuropharmacology, 65, 213-22 (2013)<br></p>