Amines

<p>BI-1467335 HCl(BI 1467335) is a selective, orally active inhibitor of semicarbazide-sensitive amine oxidase (SSAO) that helps improve chronic obstructive</p>

<p>5(6)-TAMRA SE (5(6)-Carboxytetramethylrhodamine N-succinimidyl ester) is the amine-reactive, mixed isomer form of TAMRA.</p>

<p>5(6)-Carboxyfluorescein (5-(and-6)-Carboxyfluorescein mixed isomers) contains a carboxylic acid that can be used to react with primary amines via carbodiimide</p>

<p>Applications N-Methyl-N-nitroso-1-octadecylamine was found to present in various hair-care products when investigated through thermal energy analyzer.<br>References Morrison, J.B., et al.: Food. Chem. Toxicol., 21, 69 (1983); Rainey, W.T., et al.: Biomed. Mass. Spec., 5, 395 (1978);<br></p>

<p>Applications (S)-2-Amino-4-[(3-aminopropyl)amino]-butanoic Acid is used in the reaction of carboxynorspermidine decarboxylase of Vibrio alginolyticus.<br>References Nakao, H., et al.: J. Gen. Microbiol. 136, 1699-704 (1990)<br></p>

<p>Stability Stable at RT<br>Applications An intermediate used for the sythesis of xanthine derivatives.<br>References Daly, J.W., et al.: J. Med. Chem., 28, 487 (1985), Erickson, R.H., et al.: J. Med. Chem., 34, 3405 (1991),<br></p>

<p>Applications 1,3,5-Benzenetriamine could have cosmetic applications. It could be used for colouring hair with nitrile-containing dyes.<br>References Suenger, G., et al.: PCT Int. Appl. (2005), WO 2005120445 A2<br></p>

<p>Applications Ammonium Nonanoate is the salt form of n-Nonanoic Acid (N649385), which is commonly used in conjunction with glyphosate, a non-selective herbicide, for a quick burn-down effect in the control of weeds in turfgrass. It is also used in the preparation of plasticizers and lacquers.<br>References Pline, W., et al.: Weed Technol., 14, 667 (2000); Frade, J., et al.: Anal. Bioanal. Chem., 395, 2167 (2009);<br></p>

<p>Applications 1-Propylamine is used in the synthesis of pyrimidine derivatives as novel and highly potent PDE4 inhibitors. Also used in the preparation of fluorenone analogs with DNA topisomerase I inhibitors.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Goto, T. et al.: Bioorg. Med. Chem., 21, 7025 (2013); Lee, C. et al.: Bioorg. Med. Chem. 21, 7125, (2013);<br></p>

<p>Applications Benzylamine Hydrochloride (cas# 3287-99-8) is a useful research chemical.<br></p>

<p>Applications 4-Chlorophenylamine is an organic chemical reagent and precursor in the synthesis of various drugs and dyestuffs. It is a building block and a degredation product of Chlorhexidine (C335045), an antiseptic as well as azo dyes and pigments in printing and textiles.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Leucea, D. et al.: Ind. Text., 61, 304 (2010); Below, H. et al.: Microchim. Acta 146, 129 (2004);<br></p>

<p>Applications 4-Amino-nicotinonitrile<br></p>

<p>Stability Hygroscopic<br>Applications N-[4-[(4-Hydroxyphenyl)amino]phenyl]acetamide is used in the synthesis of lithographic plates.<br></p>

<p>Stability hygroscopic<br>Applications 3-Amino-1-propanol is used in the synthesis of tetrathiafulvalenes displaying optical and electrochemical properties. Also used in the synthesis of lipid-like materials for the delivery and encapsulation of RNAi therapeutics.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ignatenko, E. et al.: Russ. J. Org. Chem., 49, 1379 (2013); Akinc, A. et al.: Nat. Biotech., 26, 561 (2008);<br></p>

<p>Applications Trimethyl-tetradecylammonium chloride,99% (cas# 4574-04-3) is a useful research chemical.<br></p>

<p>Stability Store in freezer at -20°C<br>Applications 2-Amino-5-cyclopropyl-1,3,4-thiadiazole (cas# 57235-50-4) is a compound useful in organic synthesis.<br></p>

<p>Applications IHydroxylamine, is a useful reactant used that is mainly used as a reducing agent in organic reactions.<br></p>

<p>Applications 3,4'-Diaminodiphenyl Ether, can be used for the synthesis of asymmetric soluble polyimides. It can also be used as a spacer in the preparation of glycine-based molecular tongs as inhibitors of β-amyloid peptide Aβ1-40 aggregation in vitro.<br>References Zhao, T., et al.: Suliao Gongye, 39, 20 (2011); Cellamare, S., et al.: Bioorg. Med. Chem., 16, 4810 (2008);<br></p>

<p>Applications Triphenylamine (cas# 603-34-9) is a useful research chemical.<br></p>

<p>Stability Hygroscopic<br>Applications N-​(4-​Amino-​5-​oxoheptyl)​guanidine is a biosynthetic intermediate in the study of saxitoxin gene cluster in cyanobacteria.<br>References Kellmann, R., et al.: Appl. Environ. Microbiol., 74, 4044 (2008)<br></p>

<p>Applications ((Dimethylaminomethylidene)amino)-3H-1,2,4-dithiazoline-3-thione as a novel efficient sulfur transfer reagents suitable for DNA and RNA synthesis.<br>References Guzaev, A.P., et al.: Tetrahedon Lett., 52, 434-437 (2011)<br></p>

<p>Applications N,N-Dimethylhexadecylamine is used in the synthesis of 3-(N,N-Dimethylpalmitylammonio)propanesulfonate (D461825), a zwitterionic surfactant used in the preparation of a highly efficient adsorbent for herbicides, DHAPS-Mt.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Gu, Z., et. al.: Ind. Eng. Chem. Res., 54, 4947 (2015)<br></p>

<p>Applications 5-Amino-2-chlorobenzotrifluoride is a compound useful in organic synthesis. It also performs a radioprotective activity against ionizing radiations.<br>References Blickenstaff, R. T., et al.: J. Pharm. Sci., 83, 219 (1994); Kumari, P., et al.: Org. Biomol. Chem., 16, 2049 (2018)<br></p>

<p>Applications 1-(Dimethylamino)-2-propanone is an intermediate in the synthesis of Amylocaine Hydrochloride which, is used mostly in spinal anesthesia.<br></p>

<p>Applications 4-Amino-1,3-dimethyl-5-nitrosouracil is a useful building block for organic synthesis.<br></p>

<p>Impurity Potassium Clavulanate EP Impurity M<br>Applications Bis(2-dimethylaminoethyl) Ether (Potassium Clavulanate EP Impurity M) is used in the manufacturing of flexible polyurethane foams.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 3-[(4-Bromophenyl)(methyl)amino]propanoic acid (cas# 231278-20-9) is a quinazoline derivative and an aryl iodide. 3-[(4-Bromophenyl)(methyl)amino]propanoic acid has also been used in the design, synthesis and biological evaluation of quinazoline-phosphoramidate mustard conjugates as anticancer drugs.<br>References Zhang, Y.; et al.: Bioorg. Med. Chem. Lett., 27, 1584 (2017); Lin, S.; Eur. J. Med. Chem., 127, 442 (2017).<br></p>

<p>Applications Cetyltrimethylammonium hydrogensulfate 99% (cas# 68214-07-3) is a useful research chemical.<br></p>

<p>Stability Hygroscopic, Light Sensitive<br>Applications 4-Aminophenylphosphorylcholine (cas# 102185-28-4) is a compound useful in organic synthesis.<br>References Bruderer, U., et al.: Mol. Immunol., 26, 63 (1989),<br></p>

<p>Applications Didodecylmethylamine has been used in the preparation of emodin quaternary ammonium salt derivatives with antitumor activity.<br>References Shao, J., et. al.: Eur. J. Med. Chem., 56, 308 (2012)<br></p>

<p>Applications 4-(3-Aminophenyl)-3-morpholinone is an intermediate during the preparation of imidazothiazoles as protein kinase inhibitors for treating cancers.<br>References Bamaung, N., et al.: PCT Int. Appl. (2009), WO 2009070516 A1 20090604.<br></p>

<p>Applications 4-(diethylamino)benzophenone (cas# 18127-87-2) is a useful research chemical.<br></p>

<p>Applications Diammonium salt of Phosphoric Acid, used in various chemical processes as a phosphorylating compound. Also used in the preparation of prosthetics and collagen nanocomposites due to the bone-like properties.<br>References Ezhova, Z. et al.: Russ. J. Inorg. Chem., 58, 1177 (2013); Wu, Y. et al.: Asian J. Chem., 25, 5881 (2013);<br></p>

<p>Applications 3-(methylamino)-3-oxopropanoic acid (cas# 42105-98-6) is a useful research chemical.<br></p>

<p>Impurity Acetazolamide EP Impurity G<br>Applications 5-Amino-1,3,4-thiadiazole-2-thiol is a thiadiazole derivative with antibacterial acitivity used in the preparation of herbicides as well as carbonic anhydrase inhibitors. (Acetazolamide EP Impurity G)<br>References Li, Z. et al.: Ying. Huax., 5, 54 (1988); Supuran, C. et al.: Rev. Roum. Chim., 40, 1227 (1995);<br></p>

<p>Stability Hygroscopic, Light Sensitive, Temperature Sensitive<br>Applications Ammonium geranyl pyrophosphate triammonium salt is a useful synthetic intermediate. Ammonium geranyl pyrophosphate triammonium salt is also used as a precursor to synthesize Insect Juvenile Hormone and its analogues, which are used as insecticides for crops.<br>References Ashok, M., et al.: P.Natl. Acad. Sci., 95, 2761 (1998); Sen, S. &amp; Ewing, G.: J. Org. Chem., 62, 3529 (1997)<br></p>

<p>Applications 5-Aminolevulinic Acid Hydrochloride (cas# CAS:5451-09-2) is a useful research chemical.<br></p>

<p>Applications 1-aminoindan (cas# 34698-41-4) is a useful research chemical.<br></p>

<p>Applications N-(5-Aminopentyl)acetamide is an acetylated polyamine, a promising biochemical marker for cancer and many other pathophysiological conditions.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Hakkinen, M. R., et al.: J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci., 941, 81 (2013); Paik, M., et al.: Clin. Chim. Acta, 411, 1532 (2010)<br></p>

<p>Applications PROP-2-EN-1-AMINE HCL (cas# 10017-11-5) is a useful research chemical.<br></p>

<p>Applications 5-(N-Ethyl-N-2-hydroxyethylamino)-2-penthlamine is a useful synthetic intermediate in the synthesis of Hydroxy Chloroquine (H905300/H905305); a major metabolite of Chloroquine (C379965, diphosphate salt) which is a standard anti-malarial drug.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Brocks, D., et al.: Clin. Pharmacokinet., 42, 1359 (2003); Brocks, D., et al.: Clin. Pharmacokinet., 42, 1359 (2003); Huang, S., et al.: Talanta, 64, 887 (2004); Luthman, H., et al.: Nucleic Acids Res., 11, 1295 (1983); Vezmar, M., et al.: Biochem. Pharmacol., 56, 733 (1998); Krajewski, W.A., et al.: J. Biomol. Struct. Dyn., 16, 1097 (1999)<br></p>

<p>Applications 2-[Methyl(phenylmethyl)amino]ethanol is used in the preparation of dihydropyrimidinones as sodium iodide symporter inhibitors used to regulate the accumulation of iodide in the thyroid gland. Also used in the synthesis of new class of pseudopeptides as potential inhibitors of β-sheet aggregation.<br>References Lacotte, P. et al.: ChemMedChem, 8, 104 (2013); Klein, J. et al.: Org. Lett., 14, 330 (2012);<br></p>

<p>Applications 1,3,5-Tris(4-aminophenyl)benzene (cas# 118727-34-7) is a useful reagent for catalytic asymmetric synthesis of chiral covalent compounds.<br>References Wang, J., et al.: J. Am. Chem. Soc., 142, 16915 (2020)<br></p>

<p>Applications 1,3-Diaminopropane is a common chemical reagent, used in the synthesis of 7-methoxytacrine-adamantylamine heterodimers as cholinesterase inhibitors applied in the treatment of Alzheimer’s disease. Also used in the synthesis of thrombosis inhibitors.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Spilovska, K. et al.: Molecules, 18, 2397 (2013); Smith, S. et al.: Blood, 120, 5103 (2012);<br></p>

<p>Applications Tert-butyl 4-Aminobutanoate Hydrochloride is used as a substance in the prevention of drug-induced memory impairement by immunopharmacotherapy.<br>References Treweek, J. B., et al.: J. Med. Chem., 51, 6866 (2008)<br></p>

<p>Applications 2-(3,4-Diethoxyphenyl)ethanamine is a useful intermediate in the preparation of Drotaverine hydrochloride, an antispasmodic drug arising from papaverine class of biologically active compounds.<br>References Turks, M., et al.: Rigas Tehniskas Universitates Zinatniskie Raksti, Serija 1: Materialzinatne un Lietiska Kimija, 23, 107 (2011)<br></p>

<p>Applications 1,3-Diethyl-6-aminouracil (cas# 41740-15-2) is a compound useful in organic synthesis.<br></p>

<p>Applications Octylamine is used as a reactant in the synthesis of 2H-indazoles and 1H-indazolones which are used as myeloperoxidase(MPO) inhibitor.<br> E0<br>References Roth, A., et al.: Bioorg. Med. Chem., 22, 6422 (2014);<br></p>