Amines

<p>Applications 5-(4-aminophenyl)-1,3,4-oxadiazole-2-thiol (cas# 32058-82-5) is a useful research chemical.<br></p>

<p>Applications 3-Amino-2-(formylamino)-3-iminopropanamide is a Temozolomide (T017775) impurity. Temozolomide acts as a imidazotetrazine alkylating agent. An antineoplastic.<br>References Newlands, E.S., et al.: Cancer Treat. Rev., 23, 35 (1997), Kim, C., et al.: J. Biol. Chem., 274, 1233 (1999), Hait, W., et al.: Cancer Res., 69, 1263 (2009),<br></p>

<p>Applications 1-Phenyl-2-(p-tolyl)ethylamine is an intermediate used to prepare γ-nitroaldehydes with quaternary stereogenic centers.<br>References Angewandte Chemie, International Edition, 52, 7228 (2013)<br></p>

<p>Applications 1-(2-Phenylethynyl)cyclohexanamine is a reactant that functions as a catalyst in the cyclization of propargylamines.<br>References Zhao, D. et al.: ChemCatChem., 9, 4598 (2017); Yuan, R. et al.: J. Org. Chem., 82, 3639 (2017);<br></p>

<p>Applications Ammonium bisulfite - In water (cas# 10192-30-0) is a useful research chemical.<br></p>

<p>Applications trans-4-(Dimethylamino)-3-buten-2-one is an reagent used in the synthetic preparation of various substances.<br>References Maggiulli, C.A., et al.: Org. Prep. Pro. Int., 16, 31 (1984); Afarinkia, K., et al.: Sci. Syn., 14, 275 (2003);<br></p>

<p>Stability Volatile<br>Applications rac 1,2-Diaminopropane is used as model precursor in the electron induced deposition of amorphous carbon nitride films. It is also used to synthesize cage peroxide, 1,6-diaza-3,4,8,9-tetraoxa-11-methylbicyclo[4.4.2]dodecane.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Wnuk, J., et al.: J. Phys. Chem., 113, 12345 (2009); Edward, J., et al.: Can. J. Chem., 77, 1057 (1999)<br></p>

<p>Applications [2-(4-Fluorophenyl)cyclopropyl]amine hydrochloride is a synthetic intermediate in the preparation of thiazolinone 4-monosubstituted quinolines as CDK1-Cyclin B inhibitors for use as anti-cancer agents.<br>References Tsai, T.Y., et al.: Bioorg. Med. Chem., 17, 2388 (2009); Vallgaarda, J., et al.: J. Med. Chem., 39, 1485 (1996);<br></p>

<p>Applications N-(2-Chloroprop-2-en-1-yl)-2,3-dihydro-1H-inden-1-amine is related to the drug Rasagiline(R126030). Rasagiline is used to increase the availability of dopamine at striatal receptors as a method to treat Parkinson’s disease.<br>References Youdim, M.B.H., et al.: Br. J. Pharmacol., 132, 500 (2001); Finberg, J.P., Rambam Maimonides Med. J., 1 (2010)<br></p>

<p>Applications N,N'-Diaminoguanidine Monohydrochloride is an analyte for HPLC. It also functions as an intermediate for the synthesis of energetic salts or materials based on dinitroguanidine.<br>References Shen, K., et al.: Huaxue Gongye Yu Gongcheng Jishu, 35, 74 (2014); Hu, B., et al.: Aust. J. Chem., 67, 1037 (2014); Zhang, Y., et al.: Chem. - A Eur. J., 18, 987 (2012)<br></p>

<p>Applications 2-(4-Amino-2-ethoxyphenyl)pthalimide (cas# 106981-52-6) is a compound useful in organic synthesis.<br></p>

<p>Applications Used for the preparation of dihydrouracils as anti-ictogenic or anti-epileptogenic agents.<br>References Akoulitchev, S., et al.: Nature, 377, 557 (1995), Marshall, N., et al.: J. Biol. Chem., 270, 12335 (1995), Marshall, N., et al.: J. Biol. Chem., 271, 27176 (1996), Shapiro, G., et al.: J. Clin. Oncol., 24, 1770 (2006),<br></p>

<p>Applications Benzyltrimethylammonium dichloroiodate is used in the mechanism of oxidation.<br>References Srinivasan, N., et al.: Tetrahedron, 30, 419 (1974), Sankhla, R., et al.: J. Chem. Res., 0465 (2002),<br></p>

<p>Applications TETRAMETHYLAMMONIUM BOROHYDRIDE (cas# 16883-45-7) is a useful research chemical.<br></p>

<p>Applications N4-Aminocytidine (cas# 57294-74-3) is a useful research chemical.<br></p>

<p>Applications 4-(dimethylamino)benzenesulfonamide (cas# 6162-21-6) is a useful research chemical.<br></p>

<p>Applications Used in the preparation of (R)-Sulforaphane (S699105).<br></p>

<p>Applications 2-(bis(2-(tert-butoxy)-2-oxoethyl)amino)acetic acid (cas# 171557-31-6) is a useful research chemical.<br></p>

<p>Applications Mono and dibasic phosphate esters are anionic surfactants which have the main feature of the stability in alkaline conditions over other surfactants. They have a wide range of properties including outstanding wetting, emulsification, lubrication, coupling activity and detergency.<br>References Ramirez, F., et al.: Tetrahedron, 35, 1581 (1979);<br></p>

<p>Applications 4-(4-Aminophenoxy)benzonitrile<br></p>

<p>Stability Air Sensitive<br>Applications Can be used as a building block for chiral ligands.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 1,2,4-Triazin-3-amine can be used as integrade inhibiting antiviral agents.<br>References Kiyama, R., et.al.: PCT Int. Appl.WO 2003016275 A1, 663, (2003);<br></p>

<p>Applications Di(3,5,5-trimethylhexyl)amine Hydrochloride is used in the preparation of N-nitrosoamines series.<br>References Wang, J., et al.: Huaxue Shiji, 31, 658 (2009)<br></p>

<p>Stability Temperature Sensitive<br>Applications A reagent which releases Nitric Oxide into aqueous solutions at controlled rates for in vitro studies.<br></p>

<p>Applications 4-(Methylamino)benzoic Acid (cas# 10541-83-0) is a compound useful in organic synthesis.<br></p>

<p>Applications 2,2-DIMETHOXY-1-PROPANAMINE (cas# 131713-50-3) is a useful research chemical.<br></p>

<p>Applications 2-cyclohexylpropan-1-amine (cas# 103254-49-5) is a useful research chemical.<br></p>

<p>Applications Tetramethylammonium Bromide (cas# 64-20-0) is a useful research chemical.<br></p>

<p>Applications Triethylamine Hydrochloride is a hydrochloride salt of triethyllamine (T775740). Triethylamine is used as a competing base for the separation of acidic basic and neutral drugs by reverse-phased high-performance liquid chromatography (HPLC). Triethylamine induces visual disturbances (such as foggy vision) in humans, and is also used in industry as a quenching agent in the ozonolysis of alkenes (e.g. (E)-2-Pentene [P227315]). Triethylamine is used in the purification of drugs which are pharmacologically or chemically similar through separation in reverse-phase HPLC (2).Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA). Environmental contaminants; Food contaminants.<br>References 1. Akesson B. et al.: Int Arch Occup Environ Health. 1986;57(4):297-302. 2. Roos RW. et al.: J Chromatogr. 1986 Dec 24;370(3):403-18.<br></p>

<p>Applications N-Ethyl-2,4-dichlorobenzylamine<br></p>

<p>Applications Ethyl 4-amino-3-fluorobenzoate<br></p>

<p>Applications (S)-Pyroglutaminol (cas# 17342-08-4) is a compound useful in organic synthesis.<br></p>

<p>Applications 2-(4-Aminophenyl)propanoic acid is a reagent in the preparation of 3-aminopyrazole inhibitors of CDK2/cyclin A as antitumor agents (Erratum).<br>References Pevarello, P., et al.: J. Med. Chem., 48, 5058 (2005);<br></p>

<p>Applications (E)-N-(2-((7-nitrobenzo[c][1,2,5]oxadiazol-4-yl)amino)ethyl)-4-oxo-4-phenylbut-2-enamide is a useful research chemical.<br></p>

<p>Stability Hygroscopic<br>Applications N-Benzyl-bis(2-chloroethyl)amine hydrochloride (cas# 10429-82-0) is a useful research chemical.<br></p>

<p>Applications 2,4-Diaminobenzenesulfonic acid (cas# 88-63-1) is a useful reagent for improving the chlorine resistance and water permeability of polyamide (PA) membrane in water treatment.<br>References Meng, Q. W., et al.: ACS Applied Mat., 12, 35393 (2020)<br></p>

<p>Stability Light Sensitive, Temperature Sensitive<br>Applications 4-(2-Aminophenyl)-4-oxo-2-butenoic Acid is a novel human lens metabolite from normal and cataractous human lenses. A UV filter.<br>References Mizdrak, J., et al.: Tetrahedron, 63, 4990 (2007); Taylor, L. M., et al.: Exp. Eye Res., 75, 165 (2002)<br></p>

<p>Applications Isopropyl 3-Aminocrotonate (cas# 14205-46-0) is a compound useful in organic synthesis.<br></p>

<p>Applications 3,4-Diaminophenol (cas# 615-72-5) is a useful research chemical.<br></p>

<p>Stability Hygroscopic<br>Applications Ethyl (Z)-[2-amino-4-thiazolyl](methoxyimino)acetate is used in the preparation of ceftriaxone-d3 (C245002), which is a labelled antibacterial.<br>References Reiner, R., et al.: J. Antibiot., 33, 783 (1980)<br></p>

<p>Applications 1-Amino-3,6,9-trioxaundecanyl-11-ol (cas# 86770-74-3) is a compound useful in organic synthesis.<br></p>

<p>Applications Tetra-N-octylammonium iodide (CAS# 16829-91-7) is a tetraalkylammonium salt and a useful nitrogen-containing building block. Tetra-N-octylammonium iodide is also used as a solid extrantant for platinum and gold in analysis of natural objects.<br>References Dmitriev, S.; et al.: Anal. Sci., 7, 65 (1991).<br></p>

<p>Applications Nonoxidative coloring agent for semipermanent coloring of keratin fibers such as hair and wool.<br>References Chen, C., et al.: Science, 279, 851 (1998), Nitz, M., et al.: Chembiochem., 4, 272 (2003),<br></p>

<p>Applications 9,10-Dihydroergotamine N-Oxide is a useful synthetic compound.<br></p>

<p>Applications N-Ethyl-3-phenylpropylamine is an intermediate in the synthesis of 4-Hydroxy Alverine (H827950), a metabolite of Alverine (A575780) in plasma.<br>References Bouvier, M., et al.: Gastroenterol. Clin. Biol., 16, 334 (1992), Mitchell, S., et al.: Aliment. Pharmacol. Ther., 16, 1187 (2002), Hayase, M., et al.: Br. J. Pharmacol., 152, 1228 (2007),<br></p>

<p>Applications Ethyl trans-2-(4-aminocyclohexyl)acetate, HCl<br></p>

<p>Applications 2-[2-(2-azidoethoxy)ethoxy]ethanamine (cas# 166388-57-4) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 5-Amino-2-bromobenzoic acid (cas# 2840-02-0) is a useful research chemical.<br></p>

<p>Applications Cyclopent-3-enamine hydrochloride (cas# 91469-55-5) is a useful research chemical.<br></p>

<p>Impurity Tiamulin Hydrogen Fumarate Impurity C<br>Applications Reagent used in the addition of Thiobistriethylamine.<br>References Evers, M., et al.: Bioorg. Med. Chem. Lett., 13, 4415 (2003),<br></p>

<p>Applications Methyl 2-Aminothiazole-5-carboxylate (cas# 6633-61-0) is a compound useful in organic synthesis.<br></p>

<p>Applications Amino(3-​chlorophenyl)​acetic Acid functions as intermediate useful in the preparation of synthetic penicillins, also used in the structure-activity relationship examination of several drugs containing the benzyl moiety, their roles in biochemical and pharmacological processes.<br>References Hansch, C., et al.: J. Med. Chem., 13, 957 (1970); Holdrege, C. T., et al.: Can. (1975), CA 966853 A2 19750429;<br></p>

<p>Applications N-[(2,4-Difluorophenyl)methyl]-2,4-difluoro-benzenemethanamine is derived from 2,4-Difluorobenzylamine (D45085), which acts as a reagent for the design of pyrazole derivatives as non-nucleoside heptatitis B virus inhibitors. It is also used as a reagent in the preparation, HIV antiviral activity, SAR, and molecular modelling of hydroxypyridonecarboxylic acids as HIV reverse transcriptase inhibitors.<br>References Jia, H., et al.: Eur. J. Med. Chem., 123, 202 (2016); Kankanala, J., et al.: J. Med. Chem., 59, 5051 (2016)<br></p>

<p>Applications ethyl 3-aminobutanoate (cas# 5303-65-1) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 5-(Aminomethyl)-2,3-dihydro-1H-inden-1-one Hydrochloride is a useful research chemical for organic synthesis.<br></p>

<p>Applications 4-Aminoindan is a reactant in the preparation of a UBLCP1 proteasome phosphatase inhibitor.<br>References He, Y., et. al.: Bioorg. Med. Chem., 23, 2798 (2015)<br></p>

<p>Applications 2-aminobenzenesulfonamide (cas# 3306-62-5) is a useful research chemical.<br></p>

<p>Applications (3,3-diethoxypropyl)dimethylamine (cas# 16851-30-2) is a useful research chemical.<br>References Choi, G., et al.:Angew. Chem. Int. Ed., 57,6166(2018)<br></p>

<p>Applications 3-DI-N-PROPYLAMINO-1-PROPYNE (cas# 6323-79-1) is a useful research chemical.<br></p>

<p>Applications tert-Butyl 2-Aminobenzoate is a useful reagent for preparing alkylamino quinazolinones.<br>References Lu, C., et al.: J. Org. Chem., 83, 1154 (2018)<br></p>

<p>Applications Tetrabutylammonium Diphenylphosphinate is used as a reagent in the synthesis of the potent antiviral agent (-)-Macrolactin A and its related compounds, (+)-Macrolactin E and (-)-Macrolactinic Acid, via a Stille cross-coupling reaction.<br>References Smith, A.B., et al.: J. Am. Chem. Soc., 120, 3935 (1998)<br></p>

<p>Applications O,O-Dibutyl Phosphorodithioate is an intermediate used to prepare oligodeoxyribonucleoside phosphorodithioates.<br>References Okruszek, A., et al.: J. Org. Chem., 60, 6998 (1995)<br></p>

<p>Applications 6-Bromohexyltriethylammonium Bromide (cas# 161097-76-3) is a compound useful in organic synthesis.<br></p>

<p>Applications (Z)-Benzyl (2-Amino-2-(hydroxyimino)ethyl)carbamate is an intermediate used in the synthesis of N-((5-Hydroxy-6-oxo-4-((2,4,6-trifluorobenzyl)carbamoyl)-1,6-dihydropyrimidin-2-yl)methyl)-1,3,4-oxadiazole-2-carboxamide (H950690), which is a derivative of Raltegravir (R100305), a potent integrase (IN) inhibitor for WT and S217Q PFV IN.<br>References Hare, S., et al.: Proc. Natl. Acad. Sci. U. S. A., 107, 20057 (2010); Hicks, C., et al.: Clin. Infect. Dis., 48, 931 (2009); Moss, D., et al.: Antimicrob. Agents Chemother., 56, 3020 (2012); Hare, S., et al.: Mol. Pharmacol., 80, 565 (2011)<br></p>