Amines

<p>Applications 4,6-Diaminoquinazoline is used in the preparation of potential nociceptin receptor (NOP) antagonists. 4,6-Diaminoquinazoline is a predicted metabolite of 6-Amino-4-(4-phenoxyphenylethylamino)quinazoline (A621350).<br>References Sestili, I. et al.: Eur. J. Med. Chem., 39, 1047 (2004);<br></p>

<p>Applications Mevinolinic Acid, Monoammonium Salt can be used as reactant/reagent in process for the preparation of the Simvastatin precursor, 2,2-dimethylbutanoic acid (1S,3R,7S,8S,8aR)-8-[(3R,5R)-7-(cyclopropylamino)-3,5-dihydroxy-7-oxoheptyl]-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-1-naphthalenyl ester, via an amidation reaction.<br>References Khanna, J., et al.: Indian, IN 184809 A1 20000930 (2000)<br></p>

<p>Applications 2-(3-Aminopropylamino)ethanol is the hydroxy analogue of WR-1065 (A576820), a metabolite of Amifostine (A576810). Amifostine is an organic thiophosphate that has the ability to protect a broad range of tissues from cytotoxicity (e.g. from chemotherapeutic agents) without inducing an antitumour response. 2-(3-Aminopropylamino)ethanol is also used as an nucleophilic tag in the detection of human butyrylcholinesterase adducts.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Antonadou, D., et al.: Int. J. Rad. Oncol. Biol. Phys., 52, 739 (2002); Kemp, G., et al.: J. Clin. Oncol., 14, 2101 (1996)<br></p>

<p>Applications 5-Bromopentyltrimethylammonium Bromide (cas# 15008-33-0) is a compound useful in organic synthesis.<br></p>

<p>Applications 6-AZIDOHEXAN-1-AMINE (cas# 349553-73-7) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications Ethyl (Z)-3-(Dimethylcarbamoylamino)-4,4,4-trifluoro-but-2-enoate is an intermediate in the synthesis of Tiafenacil (T436300), which is a uracil herbicide used as a pesticide for the prevention and control of plants.<br>References Peng, X., et al. Faming Zhuanli Shenqing, 68pp Patent 2018 CODEN:CNXXEV<br></p>

<p>Applications 2-Aminobenzenesulphonic acid (cas# 88-21-1) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 3-Amino-1,2-propandiol is used in the synthesis of Decarbazolyl Carvedilol (D212720), a metabolite of Carvedilol (C184625) found in humans, rats, dogs and mice.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Schaefer, W.H. et al.: Drug. Metab. Dispos., 26, 958 (1998); Neugebauer, G. &amp; Neubert, P.: Eur. J. Drug. Metabol. Ph., 16, 257 (1991); Neugebauer, G. et al.: J. Cardiovasc. Pharm., 10, S85 (1987)<br></p>

<p>Applications 5-Iodo-2-aminoindane<br></p>

<p>Applications Intermediate in the preparation of Trimebutine metabolites.<br></p>

<p>Applications 2-((tert-bButoxycarbonyl)amino)-2-(hydroxymethyl)-4-(4-octylphenyl)butyl Acetate is the intermediate in the synthesis of Mono-O-acetyl Fingolimod TFA (F524600), which is an impurity of Fingolimod (F805000, HCl salt) which is a novel immune modulator that prolongs allograft transplant survival in numberour models by inhibiting lymphocyte emigration from lymphoid organs.<br>References Brinkmann, V., et al.: Transplantation, 72, 764 (2001). Brinkmann, et al.: J. Biol. Chem., 277, 24, 21453 (2002). Mtaloubian, M., et al.: Nature, 427, 355 (2004)<br></p>

<p>Applications N-(4-amino-2-chlorophenyl)-5-chloro-2-hydroxybenzamide (cas# 10558-45-9) is a useful research chemical.<br></p>

<p>Applications A compound used in anti-corrosive coating material for the prevention of corrosion in metals.<br>References Weng, C. et al.: Chem. Mat., 22, 2075 (2011);<br></p>

<p>Applications 2-(Aminosulfonyl)benzoic Acid can be used as reactant/reagent in synthesis and pharmacological activity of γ-(phenyloxamido)- and γ-(phenylsulfonyloxamido)butanoic acids.<br>References Georgiyants, V. A., et al.: Farmatsevtichnii Zhurnal, 2, 34 (2010);<br></p>

<p>Applications (±)-trans-1,2-Diaminocyclohexane is a reagent used in the thyroid receptor agonists for treatment of androgenetic alopecia.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Li, J. J., et al.: Bioorg. Med. Chem. Lett., 20, 306 (2010)<br></p>

<p>Applications Ethylammonium Thiocyanate is used in the study of protic ionic liquid nanostructure.<br>References Hayes, R., et al.: Angewandte Chemie, International Edition, 52, 4623 (2013); Murphy, T., et al.: J. Phys. Chem., 118, 12017 (2014)<br></p>

<p>Applications methyl amino(2-bromophenyl)acetate hydrochloride (cas# 1219408-44-2) is a useful research chemical.<br></p>

<p>Applications 9,10-Dihydroergotamine N-Oxide is a useful synthetic compound.<br></p>

<p>Applications pentan-2-amine hydrochloride (cas# 76716-21-7) is a useful research chemical.<br></p>

<p>Applications Ammonium Bromide is used as a bromide activated chloramine biocide for effective control of volatile fatty acids and catalase and biofilm elimination in paper making industry. Also applied in biopharmaceuticals and dosage form designs.<br>References Bharati, S., et al.: Appita J., 56, 426 92003); Torosian, G., et al.: Am. J. Hosp. Pharm., 30, 716 (1973)<br></p>

<p>Stability Hygroscopic<br>Applications 1-Amino-3-Hydroxybenzene is used in the preparation of inhibitors of mammalian carbonic anhydrase isoforms. Also used in the preparation of quinoline tethered fluorescent carbon dots for regulated anticancer discovery.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Carta, F. et al.: Bioorg. Med. Chem., 21, 1564 (2013); Karthik, S. et al.: Chem. Comm., 49, 10471 (2013);<br></p>

<p>Applications 2-Benzylthio-5-amino-1,3,4-thiadiazole is used to study and investigate its antitumor activities against human cervix adenocarcinoma(HeLa), human liver cancer cell(SMMC-7721), human breast cancer cell(MCF-7) and human lung cancer cell(A549) lines that isfurther evaluated by CCK-8 assay.<br>References Zhao, J., et. al., Chem. Res. Chin. Univ.,30, 764-769 (2014)<br></p>

<p>Applications 2-Amino-2-cyclopropylpropanenitrile, is an enamine building block that can be used in the synthesis of various chemical compounds, such as in synthesis of 5-substituted hydantoins, and Ketone-Derived Enamides.<br>References Murray, R. G. et al.: Organic &amp; Biomolecular Chemistry, Vol: 6, P: 988-99 1 (2008); Coussanes, G. et al.: euro. J. Org. Chem, Vol 2016, P: 4176-4188 (2016);<br></p>

<p>Applications (Z)-Benzyl (2-Amino-2-(hydroxyimino)ethyl)carbamate is an intermediate used in the synthesis of N-((5-Hydroxy-6-oxo-4-((2,4,6-trifluorobenzyl)carbamoyl)-1,6-dihydropyrimidin-2-yl)methyl)-1,3,4-oxadiazole-2-carboxamide (H950690), which is a derivative of Raltegravir (R100305), a potent integrase (IN) inhibitor for WT and S217Q PFV IN.<br>References Hare, S., et al.: Proc. Natl. Acad. Sci. U. S. A., 107, 20057 (2010); Hicks, C., et al.: Clin. Infect. Dis., 48, 931 (2009); Moss, D., et al.: Antimicrob. Agents Chemother., 56, 3020 (2012); Hare, S., et al.: Mol. Pharmacol., 80, 565 (2011)<br></p>

<p>Applications Tetrabutylammonium tetrafluoroborate (cas# 429-42-5) is a useful research chemical.<br></p>

<p>Applications N-[3-(4-Aminophenyl)propyl]-N,N-dimethylamine<br></p>

<p>Applications 3,4-Diaminophenol (cas# 615-72-5) is a useful research chemical.<br></p>

<p>Applications O-Cyclopropylmethyl-hydroxylamine, Hydrochloride (cas# 74124-04-2) is a compound useful in organic synthesis.<br></p>

<p>Applications (9H-Purin-6-ylamino)-acetic acid (cas# 10082-93-6) is a useful research chemical.<br></p>

<p>Stability Air Sensitive<br>Applications Aminophenethylamine is an efficient sorbent for the separation of dopamine.<br>References Lulinski, P., et al.: Talanta, 119, 623 (2014)<br></p>

<p>Applications (1S,3R,4S)-Ethyl 4-Amino-3-((tert-butoxycarbonyl)amino)cyclohexanecarboxylate Oxalate has been used as a reactant for the preparation of oxadiazole compounds containing cyclohexanediamine moiety.<br></p>

<p>Applications Used in the preparation of (R)-Sulforaphane (S699105).<br></p>

<p>Applications Ethyl trans-2-(4-aminocyclohexyl)acetate, HCl<br></p>

<p>Stability Air Sensitive<br>Applications Can be used as a building block for chiral ligands.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications Tetra-N-octylammonium iodide (CAS# 16829-91-7) is a tetraalkylammonium salt and a useful nitrogen-containing building block. Tetra-N-octylammonium iodide is also used as a solid extrantant for platinum and gold in analysis of natural objects.<br>References Dmitriev, S.; et al.: Anal. Sci., 7, 65 (1991).<br></p>

<p>Applications Benzyl (2S)-2-carbobenzyloxyamino-6-hydroxyhexanoate (cas# 84246-49-1) is a compound useful in organic synthesis.<br></p>

<p>Applications 2,2-Diethoxy-N-ethylethanamine is used in the preparation of 1-substituted-2-mercaptoimidazoles with antithyroid activity.<br>References Jones, R.G.J. Am. Chem. Soc., 71, 4000 (1949)<br></p>

<p>Applications B-[3-[[2-Hydroxy-3-[3-(triethoxysilyl)propoxy]propyl]amino]phenyl]boronic acid was prepared for the use as porous polymeric monolith for the specific capture of cis-​diol-​containing flavone under neutral condition.<br>References Pan, J., et al.: Chem. Eng. J., 317, 317-330 (2017);<br></p>

<p>Applications Lactosamine forms the backbone of several cell surface glycans such as sialylated glycans or keratin sulfates. Also, it is a basic structural element of Lewis type, and human milk oligosaccharides.<br>References Karoly, A., et al.: Tetrahedron Lett., 57, 2595-2597 (2016)<br></p>

<p>Applications O,O-Dibutyl Phosphorodithioate is an intermediate used to prepare oligodeoxyribonucleoside phosphorodithioates.<br>References Okruszek, A., et al.: J. Org. Chem., 60, 6998 (1995)<br></p>

<p>Applications Trimethylphenylammonium tribromide is a brominating agent, and is also used as an oxidizing agent in the preparation of disulfides and sulfoxides from thiols and sulfides.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ghorbani-Choghamarani, A., et al.: Phosphorus Sulfur, 186, 1665 (2011); Gonzalez, A., et al.: Phytochemistry, 12, 1113 (1973)<br></p>

<p>Applications 3-Amino-4-hydroxybenzoic acid (cas# 1571-72-8) is a useful research chemical.<br></p>

<p>Applications 3-DI-N-PROPYLAMINO-1-PROPYNE (cas# 6323-79-1) is a useful research chemical.<br></p>

<p>Applications 4-(Ethylmethylamino)butanal Diethyl Acetal is a useful research chemical.<br></p>

<p>Applications An intermediate of Synergistin. Antibacterial.<br></p>

<p>Applications 4-(2-Amino-3,3-dimethyl-1-oxobutyl)benzonitrile hydrochloride is used as a reagent to synthesize phenyloxobutanylpyridinylpiperazinecarboxamide derivatives, compounds that have TRPA1 receptor antagonistic properties.<br>References Svensson, M. &amp; Weigelt, D. Preparation of Phenyloxobutanylpyridinylpiperazinecarboxamide Derivatives for Use as TRPA1 Receptor Antagonist. PCT Int. Appl. 2012050512. Apr 19, 2012.<br></p>

<p>Applications Degradation of Acid Black 1 reveals the formation of 3-Aminocatechol as one of the intermediates.<br>References Krishnakumar, B., et al.: Desalin. Water. Treat., 24, 132 (2010).<br></p>

<p>Applications 5-Amino-1,2,3-thiadiazole, as a thiadiazole derivative, is a privileged structure in medicinal chemistry and has been investigated for anticonvulsant and antimicrobial activities.<br>References Matsumoto, T., et al.: Masakuni; PCT Int. Appl. (2006), WO 2006054652 A1 20060526; Gommaa, A., et al.: Alexandria J. Pharm. Sci., 5, 153 (1991)<br></p>

<p>Applications A potent γ-ketoaldehyde scavenger that has been shown to protects cardiac sodium channel (NaV1.5) from oxidant-induced inactivation<br>References Zagol-Ikapitte, I. et al.: Pharmaceutics, 2, 18 (2010); Nakajima, T. et al.: J. Mol. Cell. Cardiol., 48, 352 (2010); Davies, S.S. et al.: Biochem., 45, 15756 (2006);<br></p>

<p>Applications ethyl 3-amino-3-oxopropanoate (cas# 7597-56-0) is a useful research chemical.<br></p>

<p>Applications (S)-3-Aminobutan-1-ol can be used as an intermediate in the preparation of compounds having HIV integrase inhibitory activity.<br>References Johns, B. et al.: J. Med. Chem., 56, 5901 (2013);<br></p>

<p>Applications 5-(Aminomethyl)-2,3-dihydro-1H-inden-1-one Hydrochloride is a useful research chemical for organic synthesis.<br></p>

<p>Applications Ethyl 3-Aminocrotonate is used as a reagent to synthesize Nitrendipine (N490150), a calcium channel antagonist that is used to treat patients with hypertension. Ethyl 3-Aminocrotonate is also used as a reagent to synthesize (S)-Felodipine (F232370), a calcium entry blocker that has antihypertensive properties.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bailey, D., et al.: Clin. Invest. Med., 12, 357 (1989); Bean, B.: Proc. Nat. Acad. Sci., 81, 6388 (1984); Kwon, K., et al.: Tetrahedron, 67, 10222 (2011); Leenen, F. &amp; Holiwell, D.: Am. J. Cardio., 69, 639 (1992); Meyer, H., et al.: Arz. Forsch., 33, 1528 (1983); Stoepel, K., et al.: Arz. Forsch., 31, 2056 (1980)<br></p>

<p>Applications 2,4-Diaminobenzenesulfonic acid (cas# 88-63-1) is a useful reagent for improving the chlorine resistance and water permeability of polyamide (PA) membrane in water treatment.<br>References Meng, Q. W., et al.: ACS Applied Mat., 12, 35393 (2020)<br></p>

<p>Applications Ethyl 4-[[(methylphenylamino)methylene]amino]benzoate<br></p>

<p>Applications N,5-diphenyl-1,3,4-thiadiazol-2-amine (cas# 1437-57-6) is a useful research chemical.<br></p>

<p>Applications 1,11-Diaminoundecane<br></p>

<p>Applications S-(3-((4-Aminophenyl)amino)-3-oxopropyl) Methanesulfonothioate is an intermediate used in the synthesis of (E)-S-(3-((4-((4-(4-hydroxybutyl)phenyl)diazenyl)phenyl)amino)-3-oxopropyl) methanesulfonothioate (H895230), which a useful research chemical.<br></p>

<p>Applications 3-(2-Aminoethoxy)propionic Acid (cas# 144942-89-2) is a compound useful in organic synthesis.<br></p>

<p>Applications S-(+)-2-Amino-1-propanol is an aliphatic amino alcohol shown to induce an antiproliferative effect in B16 melanoma cells. S-(+)-2-Amino-1-propanol is used in the preparation of oxazolines which are often used as ligands in homogeneous catalysis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Landau, O. et al.: Cancer Lett., 69, 203 (1993); Gant, T.G. et al.: Tetrahedron, 50, 2297 (1994);<br></p>