Amines

<p>Applications Aromatic amines likely to have high carcinogenic potency. QSARs of aromatic amines.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Franke, R., et al.: Carcinogenesis, 22, 1561 (2001), Benigni, R., et al.: Chem. Rev., 105, 1767 (2005), Benigni, R., et al.: Environ. Mol. Mutagen., 50, 152 (2009),<br></p>

<p>Applications Dibenzylamine, a chemical contaminant in L-(+)-β-hydroxybutyrate, exhibits direct anticonvulsant actions in vivo.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Rho, J.M., et al.: Epilepsia, 43, 358 (2002)<br></p>

<p>Applications Diethylamine Hydrochloride is a secondary amine and a precursor of Atrazine (A794600). It is used as a reactant if the production of pesticides, dyes and pharmaceutical compounds.<br>References Raghuram, P. et al.: Chromatograph., 71, 963 (2010); Smith, D. &amp; Crowley, D.: FEMS Microbiol. Ecol., 58, 271 (2006); Asiri, A.: Dyes and Pigments., 42, 209 (1999); Rijhsinghani, K. et al.: Canc. Det. Prev., 5, 283 (1982)<br></p>

<p>Applications Aminobutanol is used in the preparation of CDK inhibitors.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Wang, J. et al.: Chin. J. Chem., 31, 1181 (2013); Tahghighi, A. et al.: J. Enz. Inhib. Med. Chem., 28, 843 (2013);<br></p>

<p>Applications (R)-(-)-2-Amino-1-butanol (cas# 5856-63-3) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Stability Hygroscopic, Light Sensitive<br>Applications 6-Hydroxydopamine is a selective catecholaminergic neurotoxin. Studies show that 6-Hydroxydopamine can be used to create an animal model of Parkinson's disease as it causes almost complete destruction of nigral dopaminergic neurons and their striatal terminals when injected into the substantia nigra of rats. 6-Hydroxydopamine induces apoptosis in PC12 cells.<br>References Soto-Otero, R. et al.: J. Neurochem., 74, 1605 (2000); Fujita, H. et al.: Brain Res., 1113, 10 (2006); Breese, G.R. et al.: 174, 313 (1970);<br></p>

<p>Impurity Brimonidine EP Impurity C<br>Applications 6-Quinoxalinamine is used in the synthetic preparation and evaluation of novel nitroheterocyclic hypoxic markers for solid tumor.<br>References Zhu, W., et al.: Bioorg. Med. Chem., 16, 3255 (2008)<br></p>

<p>Applications O-2-Propynylhydroxylamine hydrochloride (cas# 21663-79-6) is a useful research chemical.<br></p>

<p>Applications sec-​Butylamine is a simple organic compound used as a building block in pharmaceutical synthesis and organic reactions.<br>References Attorresi, C. et al.: Org. Biomol. Chem., 16, 8944 (2018);<br></p>

<p>Applications (S)-2-Amino-4-[(3-aminopropyl)amino]-butanoic Acid is used in the reaction of carboxynorspermidine decarboxylase of Vibrio alginolyticus.<br>References Nakao, H., et al.: J. Gen. Microbiol. 136, 1699-704 (1990)<br></p>

<p>Applications N-(5-Aminopentyl)acetamide is an acetylated polyamine, a promising biochemical marker for cancer and many other pathophysiological conditions.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Hakkinen, M. R., et al.: J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci., 941, 81 (2013); Paik, M., et al.: Clin. Chim. Acta, 411, 1532 (2010)<br></p>

<p>Applications 2-(Diphenylmethoxy)-N-ethylamine (cas# 17349-94-9) is a compound useful in organic synthesis.<br></p>

<p>Applications 4-Aminobenzamide (cas# 2835-68-9) is a useful research chemical.<br></p>

<p>Applications Triphenylamine (cas# 603-34-9) is a useful research chemical.<br></p>

<p>Stability Moisture Sensitive<br>Applications Tetrabutylammonium Difluorotriphenylsilicate is used as a reagent in the synthesis of (S)-N-(3-(3,6-dibromo-9H-carbazol-9-yl)-2-fluoropropyl)-6-methoxypyridin-2-amine ((-)-P7C3-S243); a neuroprotective chemical with improved druglike properties.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Naidoo, J., et al.: J. Med. Chem., 57, 3754 (2014)<br></p>

<p>Applications Methyl 5-Aminopentanoate Hydrochloride is used as a reactant to synthesize several compounds with therapeutic potential.<br>References Larson, Peter, et al.: ACS Med. Chem. Let, 8(11), 1148-1152 (2017);Li, Yongtao, et al.: J. of Med. Chem., 61(7), 3166-3192 (2018);Lu, Yuzhi, et al.: ACS Med. Chem. Let., 7(12), 1185-1190 (2016)<br></p>

<p>Applications 2-(2-Aminoethoxy)anisole is used as an additive to vinylphosphonic acid esters and acrylonitrile forming compounds displaying hypotensive activity. An impurity from the process of Carvedilol (C184625)<br>References Reznik, V. et al.: Russ. Chem. Bull., 48, 979, (1999); Hirohashi, M., et al.: Arzneim.-Forsch., 40, 735 (1990), Packer, M., et al.: N. Engl. J. Med., 334, 1349 (1996),<br></p>

<p>Applications 2-[Methyl(phenylmethyl)amino]ethanol is used in the preparation of dihydropyrimidinones as sodium iodide symporter inhibitors used to regulate the accumulation of iodide in the thyroid gland. Also used in the synthesis of new class of pseudopeptides as potential inhibitors of β-sheet aggregation.<br>References Lacotte, P. et al.: ChemMedChem, 8, 104 (2013); Klein, J. et al.: Org. Lett., 14, 330 (2012);<br></p>

<p>Applications 4-(4,6-Bis(4-((2-ethylhexyloxy)carbonyl)phenylamino)-1,3,5-triazin-2-ylamino)benzoic Acid is an impurity in the synthesis of Ethylhexyl Triazone (E918810), used in sunscreen formulations as a UV filter to block out harmful ultraviolet light.<br>References Potard, G. et al.: Int. J. Pharm., 189, 249 (1999); Couteau, C. et al.: J. Pharm. Biomed. Anal., 44, 270 (2007);<br></p>

<p>Stability Hygroscopic<br>Applications Benzyltrimethylammonium chloride (cas# 56-93-9) is a useful research chemical.<br></p>

<p>Applications N,N,N',N'-Tetramethylethylenediamine is used as polymerization accelerator in gel electrophoresis, solvent and oxidizing reagent.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bassam, B.J., et al.: BioTechniques, 19, 568 (1995), Moham, D., et al.: J. Chromatogr., 979, 271 (2002),<br></p>

<p>Applications 3-(3-Aminobenzyl)phenylamine (cas# 19471-12-6) is a useful catalyst for creating 3D printed objects comprised of layers of cured polymers that are hit by two distinct light sources.<br>References Holt, P., et al.: U.S. Pat. Appl. Publ. (2020), US 20200282638 A1<br></p>

<p>Applications Ethylamine Hydrochloride a chemical used in various chemical organic syntheses and biological studies.<br>References Miller, M.M. et al.: Bioorg. Med. Chem. Lett., 22, 6503 (2012); Yasui, K. et al.: Prot. Sci., 19, 486 (2010);<br></p>

<p>Applications DIISOPROPYLAMINE HYDROCHLORIDE (cas# 819-79-4) is a useful research chemical.<br></p>

<p>Applications Ethylamine Solution is used as a reagent in the synthesis of a series of hexadentate ligands as potential antibacterial agents. Also used as a reagent in the synthesis of tetrahydrothiazolopyridine derivatives as potent smoothened antagonists.<br>References Zhang, M., et al.: Chem. Biol. Drug Des., 84, 659 (2014); Ma, H., et al.: Eur. J. Med. Chem., 89, 721 (2015)<br></p>

<p>Applications Hexadecyltrimethylammonium Bromide (CTAB) is a cationic surfactant used as a template in the synthesis of Mesoporous γ-Fe2O3.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Yu, H.-h., et al.: Gongneng Cailiao, 42, 2005 (2011),<br></p>

<p>Applications Reagent used to prepare Guanidine derivatives.<br>References Nozawa, D., et al.: Bioorg. Med. Chem. Lett., 11, 1481 (2001), Choudhury, A., et al.: Biochem., 46, 4066 (2007), Yuan, D., et al.: Bioorg. Med. Chem., 15, 265 (2007),<br></p>

<p>Applications Carboxymethoxyamine Hemihydrochloride (cas# 2921-14-4) is a compound useful in organic synthesis.<br></p>

<p>Applications Diethyltoluenediamine is used in preparation of hydroxyl and amino-modified anti-explosion composite materials.<br>References Wei, M., et al.: Faming Zhuanli Shenqing, (2021);<br></p>

<p>Stability Moisture Sensitive<br>Applications Used in the synthesis of novel phosphorothioates and phosphorodithioates as cholinesterase inhibitor.<br>References Sussman, J., et al.: Science, 253, 872 (1991), Mallender, W., et al.: J. Biol. Chem 1999, 274, 8491,<br></p>

<p>Stability Hygroscopic<br>Applications 4-(2-Aminoethyl)benzene-1,2-diol has been studied for its role in Parkinson's disease.<br>References Segura-Aguilar, J.: Neural Regeneration Research, 12, 897 (2017)<br></p>

<p>Applications 2-Amino-2-thiazoline (cas# 1779-81-3) is a compound useful in organic synthesis.<br></p>

<p>Applications 5-Amino-2-chlorobenzotrifluoride is a compound useful in organic synthesis. It also performs a radioprotective activity against ionizing radiations.<br>References Blickenstaff, R. T., et al.: J. Pharm. Sci., 83, 219 (1994); Kumari, P., et al.: Org. Biomol. Chem., 16, 2049 (2018)<br></p>

<p>Applications Diisopropanolamine is used as a reagent in the synthesis of pyrrolo[3,4-c]quinoline-1,3-diones as potent caspase-3 inhibitors.<br>References Kravchenko, D., et al.: Lett. Drug Des. Discov., 3, 61 (2006)<br></p>

<p>Applications N,N-Dimethyltetradecylamine (cas# 112-75-4) is a compound useful in organic synthesis.<br></p>

<p>Applications 3-Diethylaminophenol is used as a reagent in the synthesis of coumarin- and rhodamine-fused deep red fluorescent dyes.<br>References Chen, J., et al.: J. Org. Chem., 78, 6121 (2013)<br></p>

<p>Applications Has a DNA binding effect.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Mikata, Y., et al.: Chem. Pharm. Bull., 48, 477 (2000),<br></p>

<p>Applications N-benzylcyclohexanamine (cas# 4383-25-9) is a useful research chemical.<br></p>

<p>Applications N-Methyl-N-nitroso-1-hexadecanamine is a compound found in a wide range of cosmetic products and cleaning emulsions.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kamp, E.. et al.: Food. Chem. Toxicol., 29, 203 (1991); Lalljie, S. P. D., et al.: Adv. Mass. Spec., 14, 33790 (1998); Abidi, S.L., et al.: J. Chroma., 324, 209 (1985);<br></p>

<p>Applications Nitrendipine (N490150) metabolite. The pharmacokinetics of Nitrendipine was studied in the rat and 6 major metabolites were identified.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Meyer, H., et al.: Arzneim.-Forsch., 33, 1528 (1983),<br></p>

<p>Applications 1,3-Benzenedimethanamine (cas# 1477-55-0) is a useful research chemical.<br></p>

<p>Applications N,N-Dipropyl-1-propanamine is a useful building block for organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications Bis(4-tert-butylphenyl)amine could be a useful reagent for synthesizing efficient luminogens with AIE features that permit imaging the brain through an intact skull.<br>References Qin, W., et al.: Adv. Mater. (Weinheim, Germany), 32, 2000364 (2020)<br></p>

<p>Applications 5-Amino-1-pentanol is an aliphatic amino alcohol with potential plasma lipid-lowering properties. 5-Amino-1-pentanol and other amino alcohols are used as emulsifying agents in dry-cleaning soaps, wax removers, cosmetics, paints and insecticides.<br>References Bondesson, G. et al.: Acta Pharm. Suec., 11, 417 (1974); Scheers, E.M. et al.: ALTA Alt. Lab. Anim., 30,309 (2002);<br></p>

<p>Applications N-Alkyl(C12-16)-N-benzyl-N,N-dimethylammonium chloride, tech. (cas# 68424-85-1) is a useful research chemical.<br></p>

<p>Applications Dimethyldimyristylammonium bromide is a cationic surfactant used in the study of lipid raft domains in membranes.<br>References Uyama, M.; et al.: J. Oleo Sci., 67, 67 (2018).<br></p>

<p>Applications 2,6-Diaminopimelic Acid is useful in biological studies involving amino acids and amino sugars as molecular indicators of the origins of organic matter in buried tephra soils.<br>References Hobara, S., et al.: Geoderma, 373, 114449 (2020)<br></p>