Cyano-, Nitrile-

Applications Tert-butyl 3-amino-4-cyanobenzoate is a useful compound for organic synthesis.

Applications 4-Biphenylacetonitrile is a useful synthetic intermediate. It was used to study the adsorption orientation of the biphenyl derivatives on the Au colloidal surfaces with α-cyclodextrins. 4-Biphenylacetonitrile on condensation reaction with ethyl phenyl propiolate yields biphenyl derivatives of acetylenic β-ketocyanide.
References Lee, J., et al.: Bull. Korean. Chem. Soc., 30, 1637 (2009); Al-Jallo, H., et al.: J. Chem. Eng. Data, 17, 513, (1972)

Applications (2-Isocyanoethyl)-benzene is a useful synthetic intermediate. It is a reagent used in Ugi reactions to synthesize various compounds such as tetrazole and bisamide.
References Zhao, T., et al.: Org. Lett., 15, 639 (2013); Brockmeyer, F., et al.: Helv. Chim. Acta., 95, 1857 (2012)

Applications tert-Butyl 3-Cyanomorpholine-4-carboxylate is used as a reactant for the synthesis of HIV integrase inhibitors.
References Gardelli, C., et. al.: J. Med. Chem., 50, 4953 (2007); Pace, P., et. al.: J. Med. Chem., 50, 2225 (2007); Summa, V., et. al.: J. Med. Chem., 49, 6646 (2006)

Applications Methyl 2-cyanobenzoate

Applications A Wittig reagent.
References Laine, D., et al.: J. Med. Chem., 52, 5241 (2009), Nakao, A., et al.: Bioorg. Med. Chem. Lett., 19, 4607 (2009), Arakawa, Y., et al.: Chem. Pharm. Bull., 57, 167 (2009),

Applications Phenoxyacetonitrile is a building block that has been used as a reactant for the preparation of [[(oxo)pyridazinyl]phenoxy]acetonitrile derivatives to be used as vasodilators.
References Bansal, R., et. al.: Drug Dev. Ind. Pharm., 74, 296 (2013)

Applications Tetrakis(acetonitrile)palladium Bis(tetrafluoroborate) is used to prepare an α-Diimine-transition metal complex, which is used as a catalyst for polymerization of olefins. It is also a catalyst used in cross coupling reaction for C-C, C-O, and C-N bond formation.
References Feldman, J., et al.: Organometallics, 16, 1514 (1997); Johnson, L., et al.: PCT Int. Appl., WO 9623010 A2 19960801 (1996); Poppenbery, J., et al.: Surface Sci., 2011; Pijnenburg, N., et al.: Dalton Transactions, 40, 8896 (2011); Kilpin, K., et al.: Inorg. Chem., 50, 6334 (2011)

Applications Methyl Isocyanoacetate, is used in the Cu-catalyzed, diastereoselective synthesis of oxazolines (O846550).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Ideguchi, T., et al.: J. American Chem. Soc., 135, 12568 (2013);

Applications 4-(Cyanophenyl)boronic Acid Pinacol Ester is used to prepare arylparacyclophanes via Suzuki aryl cross-coupling of bromoparacyclophane with arylboronic acid and arylboronates. It’s also used to prepare tyrosine-modified analogs of α4β7 integrin inhibitor biotin-R8ERY.
References Roche, A., et al.: Org. Biomol. Chem.,, 3, 515 (2005); Papst, S., et al.: Bioorg. Med. Chem., 20, 5139 (2012)

Applications 2-Acetyl-4-cyanophenol

Applications 4-cyano-N,N-dimethylbenzamide (cas# 24167-50-8) is a useful research chemical.

Please enquire for more information about 1-Methylindole-3-acetonitrile including the price, delivery time and more detailed product information at the technical inquiry form on this page

2-fluoro-4-iodobenzonitrile is a potent inhibitor of the functions of VEGFR receptors. It inhibits the proliferation and migration of cancer cells by binding to VEGFR receptors, which are tyrosine kinases that regulate cell growth and differentiation. 2-Fluoro-4-iodobenzonitrile has been shown to inhibit angiogenesis, or the formation of new blood vessels, in vitro. This drug also has potent inhibitory activity against tumor growth in vivo. Clinical trials have shown that 2-fluoro-4-iodobenzonitrile can be used to treat various types of cancers, including breast cancer and colon cancer.

2-Cyanophenothiazine is an aliphatic hydrocarbon that belongs to the class of industrial chemicals. It is used as a reactant in organic synthesis, such as for the production of 2-cyanophenols and 2-phenylbenzimidazole. This compound can be produced by reacting n-hexane with amide or n-dimethylformamide. 2-Cyanophenothiazine has been shown to have mitochondrial biogenesis effects and increase mitochondrial membrane potential in thp-1 cells. It also has biological properties, such as being anti-inflammatory and having antitumor activity.

Please enquire for more information about 3-Cyano-1-azetidinesulfonyl chloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

(1-Methyl-1H-benzoimidazol-2-yl)-acetonitrile is a nucleophilic compound that reacts with carbanions to form alkyl benzoates. It can also act as an electrophile in the formation of nitroalkenes and amides, as well as an intermediate in the synthesis of phenazines. The potassium salt of this compound is used as a reagent in organic synthesis. (1-Methyl-1H-benzoimidazol-2-yl)-acetonitrile has been shown to react with methylene and aromatize to produce ethyl cyanoacetate, which can be used for the production of malononitrile. This reaction is catalyzed by potassium carbonate and esters.

Thiophene-3-acetonitrile is a reactive intermediate that is used in the synthesis of active enzymes. It has been shown to be an efficient method for the synthesis of antitubercular agents, such as rifamycins and other drugs. Thiophene-3-acetonitrile is an electron acceptor and can be used to generate active enzymes, such as those involved in DNA replication and transcription. This compound also has a variety of functional groups, which can be used for a number of techniques, including coordination geometry studies.

Potassium tetracyanoaurate(III) (K[AuCl4]) is a crystalline, intermetallic compound that has been used in the production of coatings, spherical particles, and electrochemical materials. The pentahydrate form has a diameter of 4.8-5.2 Å and a melting point of ~115°C. K[AuCl4] is stable in air and water but reacts with strong acids to form potassium chloride and potassium tetracyanocuprate(II). This substance also has an optimal pH range of 6-7 and an average solubility range of 0.05-0.1g/100mL at 20°C. The microstructure of K[AuCl4] is not well understood because it is difficult to isolate from other compounds during synthesis.

Potassium dicyanoargenate is an organic acid that is a precursor to silver nanoparticles. This compound is typically used in the production of cellulose derivatives, and for the activation of polymerization reactions. Potassium dicyanoargenate can also be used to produce insoluble polymers and cationic surfactants by combining it with a metal ion, such as sodium carbonate or hydroxyl groups.

4-Fluoro-3-nitrophenylacetonitrile is a monomer that can be synthesised from the reaction of carbamic acid and diphenyl ether. It is chiral, stereoselective and nucleophilic. 4-Fluoro-3-nitrophenylacetonitrile can also be synthesised by reacting fluoroacetamide with sodium cyanide in water, forming the corresponding amide, which reacts with acetonitrile to form the nitro compound. The anti-cancer properties of 4-fluoro-3 nitrophenylacetonitrile have been studied in vitro and in vivo. This substance has been shown to inhibit growth of cancer cells and induce apoptosis. In addition, this substance has been used as a synthetic strategy for dihydroisoquinolines, which are important for their anti-cancer properties.

4-(Dicyanomethylene)-2-tert-butyl-6-(1,1,7,7-tetramethyljulolidinium) (DCJTB) is a red fluorescent dye that emits light when activated by heat. DCJTB is cationic and can be polymerized thermally or chemically. The molecule has been shown to be activated by the addition of an electron donor such as a metal chelate. This reaction takes place in the solution phase. DCJTB has been used for the diagnosis of nonpolar solvents such as gasoline and oil leaks in machine parts. DCJTB has also been used to detect groundwater contamination with trichloroethylene (TCE).