Ethers

<p>Applications Ethoxybenzene is a reagent used in the synthesis of benzenesulphonylurea derivatives as anti-hyperglycaemic agents and various PTP1B inhibitors.<br>References Liu, P. et al.: Bioorg. Med. Chem., 23, 7079 (2015);<br></p>

<p>Applications Tris[[2-(tert-butoxycarbonyl)ethoxy]methyl]methylamine is used in the preparation of dendronized polymers. Tris[[2-(tert-butoxycarbonyl)ethoxy]methyl]methylamine can be used in the synthesis of optically degradable dendrons for temporary adhesion of proteins to DNA. It is also used in the preparation of tricylic polyamide receptor for carbohydrate recognition.<br>References Calderon, M. et al.: Macromol. Sym., 258, 53 (2007); Kostiainen, M.A. et al.: Chem. Eur. J., 16, 6912 (2010); Klein, E. et al.: Angew. Chem. Int. Ed., 44, 298 (2005);<br></p>

<p>Applications Ethyl 4-(2-(tert-Butoxy)-2-oxoethoxy)-3-oxobutanoate is an intermediate for the synthesis of O-Des[2-aminoethyl]-O-carboxymethyl dehydroamlodipine (D289480), which is the metablolite of Amlodipine (A633495), a long-acting calcium channel blocker that is commonly used as an anti-hypertensive in the treatment of cardiovascular conditions.<br>References Arrowsmith, J.E., et al.: J. Med. Chem., 29, 1696 (1986), Burges, R.A., et al.: J. Cardiovasc. Pharmacol., 9, 110 (1987), Haria, M., et al.: Drugs, 50, 560 (1995)<br></p>

<p>Applications 2-(Methoxyimino)-3-oxo-butanoic Acid 1,1-Dimethylethyl Ester is an intermediate used in the synthesis of Cefotaxime Bromoacetyl Analogue (C242940), which is an impurity of Cefotaxime (C242950), a broad spectrum third generation cephalosporin antibiotic.<br>References Wise, R., et al.: Antimicrob. Agents Chemother., 14, 807 (1978), Muhtadi, F.J., et al.: Anal. Profiles Drug Subs., 11, 139 (1982),<br></p>

<p>Applications 2,5-dimethoxycyclohexa-2,5-diene-1,4-dione (cas# 3117-03-1) is a useful research chemical.<br></p>

<p>Applications α-(Aminomethyl)-2-(trifluoromethoxy)benzenemethanol is an analog of α-(Aminomethyl)-3-(trifluoromethoxy)benzenemethanol (A630745); a compound that is used as a reagent in the synthesis of potent and selective ethanolamine inhibitors of bacterial phenylalanyl tRNA synthetase. It is also used as a reagent in the synthesis of 1-aryl-2-((6-aryl)pyrimidin-4-yl)amino)ethanols as competitive inhibitors of fatty acid amide hydrolase.<br>References Jarvest, R.L., et al.: Bioorg. Med. Chem. Lett., 15, 2305 (2005); Keith, J.M., et al.: Bioorg. Med. Chem. Lett., 24, 1280 (2014)<br></p>

<p>2-Methoxy-5-methylsulfonylbenzoic acid is an organic compound that can be used as a pharmaceutical intermediate. It has been used to synthesize diagnostic agents and drugs such as isradipine and sarpogrelate hydrochloride. 2-Methoxy-5-methylsulfonylbenzoic acid is also used as an intermediate in the synthesis of bortezomib, a drug that inhibits the proteasome. This product contains impurities that may interfere with its use as a pharmaceutical preparation. The flow rate of this product is sensitive to changes in temperature and pressure.</p>

<p>3-Amino-5-methoxybenzoic acid is a macrocyclist, which means that it can switch between two different forms. When the temperature is below 27 degrees Celsius, it exists as a mesomorphic phase and when the temperature increases above 27 degrees Celsius, it exists as an isotropic phase. 3-Amino-5-methoxybenzoic acid also has homologues that are also mesomorphic or isotropic depending on their temperatures. The chemoenzymatic parameters of the two phases are different and so are their lamellar morphologies. The fluorine atom in 3-amino-5-methoxybenzoic acid makes it act like a Lewis acid, decreasing its melting point and increasing its vapor pressure. There are two isomers of 3-amino-5-methoxybenzoic acid: dodecyl and octadecyl 3--amino--5--methoxyben</p>

<p>2-Bromo-4-methoxybenzaldehyde is a cyclic, stereoselectively eliminable, acrylate that can be used in the asymmetric synthesis of sulfamidate and lactam. It can also be used to synthesize quinoline derivatives with aluminium chloride. This product has been shown to yield good yields when reacted with functional groups such as halides and nature. 2-Bromo-4-methoxybenzaldehyde is found in biomolecular reactions.</p>

<p>Please enquire for more information about [1-(2-Methoxyethyl)-1H-indol-3-yl]acetic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>2-Methoxybenzenesulphonyl chloride is an enzyme inhibitor that has been shown to have anti-cancer and anti-HIV activity. It inhibits the growth of cancer cells by interfering with protein synthesis and preventing RNA transcription. 2-Methoxybenzenesulphonyl chloride has also been shown to be effective in treating chronic hepatitis, degenerative diseases, and autoimmune diseases. This drug is metabolized through a number of metabolic transformations, including oxidation by cytochrome P450 enzymes or conjugation with glucuronic acid. The pro-apoptotic protein Bax is induced by 2-methoxybenzenesulphonyl chloride in human HL60 cells, which may be due to its ability to induce transcriptional regulation.</p>

<p>4-(Butoxymethyl)-2-methoxyphenol is an antimicrobial agent that has been shown to be effective against Candida glabrata. It is a non-ionic surfactant with a C8 alkyl chain, which is derived from the reaction of butyl alcohol and phenol. 4-(Butoxymethyl)-2-methoxyphenol can be used in oral care products such as toothpaste or mouthwash. This product also has a control analysis for sodium citrate and root powder, which may be due to its fatty acid and magnesium salt content.</p>

<p>2-(2-Aminoethoxy)ethanol (2-AE) is a natural compound that has been synthesized from ethanol and 2-aminoethanol. It has been shown to react with sodium carbonate to form stable complexes that are resistant to hydrolysis by amines. The stability of the complex is attributed to the formation of an intermolecular hydrogen bond between the hydroxyl group on the 2-AE molecule and the carboxylate group on the sodium carbonate molecule. 2-AE reacts with benzalkonium chloride, a quaternary ammonium salt, in water vapor to produce an alcohol and a fatty acid, which is then hydrolyzed by glycol ethers into glycolates. This mechanism is similar to that of other reactions involving quaternary ammonium salts, such as those in fatty acids or glycol ethers.</p>

<p>S-(+)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetic acid chloride is an optical, amide, and epoxidation derivatizing agent that is used to chiralify amines. It is a liquid at room temperature with a molecular weight of 123.87 g/mol. This chemical reacts with alcohols to form esters, which can be identified by their different retention times in chromatography. It also reacts with hydroxyl groups to form ethers and esters, as well as hydroxyls on other molecules such as amino acids, peptides, and proteins. S-(+)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetic acid chloride has been used for the synthesis of bisoprolol from metoprolol and triethylphosphite.</p>

<p>1-(2-Methoxyphenyl)piperazine is a drug that has been shown to have locomotor activity, antihypertensive activity, and inhibitory properties. It also acts as a matrix effect and receptor activity. 1-(2-Methoxyphenyl)piperazine has been shown to have inhibitory effects on 5-ht7 receptors, which are mainly found in the brain. This drug binds to the 5-ht2 receptor, which is a type of serotonin receptor in the brain. The binding of 1-(2-methoxyphenyl)piperazine to the 5-ht2 receptor inhibits the release of dopamine from neurons and leads to necrotic cell death. This drug can also be used as an analytical tool for measuring 5-ht1a receptors, which is a type of serotonin receptor found in the brain.</p>

<p>4-Methoxy phenethylamine (4MPEA) is a natural compound that has been found to have biological properties. It is a precursor of dopamine and norepinephrine, which are neurotransmitters in the brain. 4MPEA is an irreversible enzyme inhibitor with a hydroxyl group. The kinetic data for this compound has been determined by nitrogen atoms. Gamma-aminobutyric acid (GABA) is involved in the regulation of neuronal excitability and plays an important role in preventing seizures. 4MPEA may have potential as a drug for treating epilepsy or other neurological disorders.</p>

<p>Please enquire for more information about tert-Butyl-n-(6-methoxy-3-pyridyl)carbamate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 5-Chloro-2-hydroxy-2-methoxycarbonyl-1-indanone including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>2(2-Ethoxyethoxy)ethanol is a glycol ether that is used as a substrate film in analytical methods, such as thin layer chromatography. It has been shown to be toxic to the liver and kidney, but not the heart. 2(2-Ethoxyethoxy)ethanol is also an experimental solubility data and can be used to measure the hydrophobic effect of organic compounds. This substance has high values for solubility, which may be due to its glycol ester type. 2(2-Ethoxyethoxy)ethanol does not show toxicity to the heart when administered orally or by inhalation, but does show toxicity to the liver and kidney at high doses.</p>

<p>3-Methoxyphenethylamine is a naturally occurring phenethylamine that is found in the human body. It is produced by the enzyme phenylethanolamine N-methyltransferase from dopamine and 3-methoxytyramine. 3-Methoxyphenethylamine can be found in the saliva, but also in the brain, muscle and kidneys. Its presence has been detected in women's breast milk. This compound has been shown to have a significant effect on chloride ion absorption and renal blood flow, as well as on 5-hydroxyindoleacetic acid levels in the urine of patients with Parkinson's disease. The predominant metabolite of 3-methoxyphenethylamine is 3-hydroxymethylphenethylamine (3HMPEA).</p>

<p>1,1-Dimethoxyethane is an organic compound that belongs to the group of isatin derivatives. It has inhibitory activity against acetal formation and can be used as a solvent in chemical reactions. 1,1-Dimethoxyethane also inhibits cancer cell growth by interfering with the production of carboxylic acids. This compound may also have therapeutic effects on Alzheimer's disease and vascular diseases such as atherosclerosis and angina pectoris.</p>

<p>Please enquire for more information about 1-(3-Methoxybenzyl)-1H-indole-3-carbaldehyde including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>3,4-Dimethoxybenzyl chloride is an acetate extract that has been shown to have anticancer properties. It is also a corrosion inhibitor with the ability to inhibit fatty acid demethylation and antimicrobial agents. It has been used in pharmaceutical preparations for treating high blood pressure, as well as in the production of eugenol, papaverine and other drugs.</p>

<p>Please enquire for more information about (2-{2-[2-(2-Aminoethyl)-4,5-dimethoxybenzyl]-4,5-dimethoxyphenyl}ethyl)amine dihydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 2-Methyl-4-(trifluoromethoxy)iodobenzene including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 1-Benzyl-5-ethoxy-1H-indole-3-carbaldehyde including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>(2S,3S)-5-[2-(Dimethylamino)ethyl]-3-hydroxy-2-(4-methoxyphenyl)-2,3-dihydro-1,5-benzothiazepin-4-one hydrochloride is a racemic mixture of two enantiomers. It is a prodrug that is hydrolyzed to its active form, diltiazem. The drug has been shown to be effective in the treatment of hypertension and angina pectoris. (2S,3S)-5-[2-(Dimethylamino)ethyl]-3-hydroxy-2-(4-methoxyphenyl)-2,3-dihydro-1,5-benzothiazepin-4-one hydrochloride has been shown to inhibit the activity of the enzyme phosphodiesterase which breaks down cyclic AMP. This inhibition results in an increase in levels of</p>

<p>4-Methoxyphenyl chloroformate is a reactive chemical that can be used to synthesize amides, esters, and anhydrides. It reacts with nucleophiles such as chloride or hydroxide to form an intermediate product. This intermediate product then reacts with the desired molecule to form the desired final product. 4-Methoxyphenyl chloroformate has shown selectivity for binding to opioid receptors, including mu and delta subtypes. This chemical may be used in the synthesis of antibiotic drugs that have similar receptor subtypes. 4-Methoxyphenyl chloroformate also has been shown to modulate G protein signaling pathways in cells, which may lead to improved pharmacokinetic properties.</p>

<p>4-(Trifluoromethoxy)aniline is a reactive intermediate used in the synthesis of pharmaceuticals, dyes, and pesticides. It is prepared by reacting hydrogen fluoride with aniline in the presence of an acid catalyst. 4-(Trifluoromethoxy)aniline can be used to synthesize epoxyeicosatrienoic acids, which are potent anti-inflammatory agents. 4-(Trifluoromethoxy)aniline has been shown to have a pharmacokinetic profile that is similar to those of other fluoroquinolones, but has not been studied for clinical development.</p>

<p>Please enquire for more information about 4-Formyl-3-methoxy-phenyloxymethyl polystyrene resin (200-400 mesh) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>6-Methoxypyridine-2-boronic acid is a boronate ligand that can be used to form coordination complexes with metals. It has been shown to interact with silver ions, which are the most effective ligands for enhancing the fluorescence of organic dyes. 6-Methoxypyridine-2-boronic acid is able to rigidify organic molecules by binding to their steric and electronic properties, making them more resistant to photodegradation. This property makes it an excellent candidate for the use in the development of fluorescent labels in analytical chemistry.</p>

<p>Please enquire for more information about 1-(4-Methoxy-pyridin-2-yl)-ethanone including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>3-(trifluoromethoxy)aniline is a compound that contains a trifluoromethoxy group. It has been shown to have antiproliferative effects in prostate cancer cells. 3-(trifluoromethoxy)aniline inhibits the activity of pim-1, which is important for cell proliferation and differentiation. The synthesis of 3-(trifluoromethoxy)aniline can be accomplished by one of two methods. In the first method, 3-chloroaniline is reacted with trifluoroacetic acid and bis(trimethylsilyl)acetamide in dichloromethane to form 3-hydroxy-4-chlorobenzenesulfonyl chloride (3HCBSCl). In the second method, the desired product is synthesized from 3-aminophenol and trifluoroacetic acid in acetonitrile. These two methods produce different isomers</p>

<p>Please enquire for more information about 1-(4-Methoxyphenyl)-3-phenyl-1H-pyrazole-5-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Ethoxylated hydrogenated castor oil is a surfactant that is often used in vitro to study cell nuclei. It has been shown to have an optimum concentration of 0.025% (v/v) in vitro assays. Ethoxylated hydrogenated castor oil also has the ability to prevent radiation-induced damage by stabilizing the cell membrane and preventing leakage of cellular contents, which can lead to cell death. This surfactant has been shown to increase synchronous fluorescence in vitro, and it is not toxic when applied topically at concentrations up to 10%. Ethoxylated hydrogenated castor oil has been found to inhibit the growth of infectious bacteria such as Chlamydia pneumoniae and Helicobacter pylori, and it may be a potential drug for treating cardiac dysfunction.</p>

<p>4-Methoxyphenylacetylene is a phosphane that has been extensively studied for its reactivity in cross-coupling reactions with electron-deficient olefins. 4-Methoxyphenylacetylene has been shown to react with chlorides and form an intermediate chloride, which reacts with an olefin to form an ether. X-ray crystal structures of the reaction mechanism have been determined. The transfer mechanism involves nucleophilic attack of chloride on the phosphorus atom followed by elimination of hydrogen chloride from the phosphorus. The reaction product is an ether.</p>

<p>Please enquire for more information about 3-(Difluoromethoxy)benzaldehyde including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>2-Bromoethoxy-tert-butyldimethylsilane is a conjugate that has been shown to have anticancer efficacy in vivo. It is a pyrimidine derivative and inhibits the viral enzyme RNA polymerase, thereby inhibiting viral replication. 2-Bromoethoxy-tert-butyldimethylsilane also inhibits glyceraldehyde 3-phosphate dehydrogenase, which is an enzyme that catalyzes the conversion of glucose into glyceraldehyde 3-phosphate and plays an important role in glycolysis. The compound has been shown to be active against mouse tumors, which are associated with endogenous retroviruses. The compound has also been shown to inhibit gapdh, an enzyme involved in energy metabolism and cancer therapy.</p>

<p>2,2'-Bis-(1-adamantyl)-4,4'-dimethoxybiphenyl is a methyl ester of adapalene. It is used to assess the effects of adapalene on the skin and to determine its marker for topical application.</p>

<p>1-(3,5-Dimethoxyphenyl)piperazine (1DMPP) is a phenylpiperazine derivative that has shown anticancer activity in vitro against human cancer cells. It is orally bioavailable and has been found to inhibit the growth of cancer cells in vivo. 1DMPP is metabolized by the liver into a number of metabolites that are excreted via the kidneys. The pharmacokinetic properties of 1DMPP have been studied in rats and mice, which revealed that it is well absorbed when administered orally and has a short terminal half-life. In vitro studies have demonstrated that 1DMPP inhibits cell growth through inhibition of protein synthesis and DNA replication.</p>

<p>Please enquire for more information about 2-[(Dimethylamino)methylene]-5-(2,3,4-trimethoxyphenyl)cyclohexane-1,3-dione including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 2-Methoxy-4-methylbenzenethiol including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 3-Amino-6,7-dimethoxy-2-methylquinazolin-4(3H)-one including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 5-Bromo-2-methoxyphenethylamine hydrobromide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Apixaban is a novel, orally active, and selective factor Xa inhibitor. It is the first oral anticoagulant that has been developed to inhibit both free and clot-bound thrombin. Apixaban binds reversibly to the active site of factor Xa and inhibits factor Xa-mediated conversion of prothrombin to thrombin, resulting in an increased concentration of prothrombin in blood. Apixaban also inhibits the activity of thrombin-activated protein C (APC) that degrades fibrin clots by proteolytic cleavage of fibrinogen. This drug has a crystalline form with a particle size between 10 and 100 μm.</p>

<p>2-(4-Methoxyphenyl)benzothiazole is a hydrogen-bond acceptor that is activated in the presence of an electron-withdrawing group. It has been shown to have anti-fungal properties and inhibitory properties against bacteria. 2-(4-Methoxyphenyl)benzothiazole also inhibits the activity of topoisomerase, which is an enzyme that controls DNA supercoiling and uncoiling, as well as DNA replication. The mechanism of this inhibition is not known, but it is thought to be due to the ability of 2-(4-methoxyphenyl)benzothiazole to form hydrogen bonds with the active site cysteine residues on topoisomerase I. 2-(4-Methoxyphenyl)benzothiazole also has been shown to be photophysical in nature, absorbing light at wavelengths of 350 nm and 480 nm and emitting light</p>

<p>Please enquire for more information about Ethyl 3-{[(1E)-(dimethylamino)methylene]amino}-5-methoxy-1-methyl-1H-indole-2-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>