Ketones

<p>Applications (2R,​3S,​4S,​5S)-5-Hydroxy-2,3,4-tris(phenylmethoxy)-5-[(phenylmethoxy)methyl]-cyclohexanone was used in the synthetic preparation of N-substituted valiolamine derivatives.<br>References Fukase, H., et al.: J. Org. Chem., 57, 3642 (1992);<br></p>

<p>Applications 4,4-Dimethoxy-2-butanone is a reactant in the synthesis of naphthalimide-naphthyridine derivatives as a fluorescent probe for the detection of hydroxyl radicals in living cells.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Meng, L., et. al.: Chem. Commun., 50, 4843 (2014)<br></p>

<p>Applications Phenoxy-2-propanone is a general chemical reagent used in the preparation of α-arylthio ketones via DL-proline.<br>References Vaquer, A. et al.: RSC Adv. 5, 96695 (2015);<br></p>

<p>Applications 1-​(3-​Hydroxyphenyl)​-​1-​propanone is a reactant used to synthesize tricyclic fused pyridines, a family of alkaloids with antimalarial activity.<br>References Zheng, L., et al.: J. Org. Chem., 81, 8911-8919 (2016)<br></p>

<p>Applications 2-Hydroxyimino-3-pentanone is an intermediate in the preparation of indole derivatives.<br>References Goya, P., et al.: J. Med. Chem., 35, 3977 (1992), Masaguer, C., et al.: Chem. Pharm. Bull., 47, 621 (1999), Wu, S., et al.: Bioorg. Med. Chem. Lett., 16, 5859 (2006),<br></p>

<p>Applications 2,2-Diethoxycycloheptanone is an intermediate in the synthesis of 1,2-Cycloheptanedione (C987255), a reagent in the synthesis of 3,3’-Polymethylene-2,2’-bibenzo[b]-1,10-phenanthrolines.<br>References Rahman, A. F. M., et al.: Heterocycles, 75, 871-877 (2008)<br></p>

<p>Applications 1,1'-(1,4-phenylene)bis-Ethanone can undergo oxidative C-C Bond Cleavage to synthesize an aryl carboxylic acid with an iodine catalyst . 1,1'-(1,4-phenylene)bis-Ethanone is also capable of Suzuki-Miyaura coupling.<br>References Xu, L.; et al.: Synlett, 29, 1505 (2018). Xia, Y.; et al.: J. Am. Chem. Soc., 140, 5347 (2018).<br></p>

<p>Applications 2-Acetylcyclohexanone is used in the synthesis of 1-(pyridyl)ethanol derivatives that can reduce keto-esters and ketones. Also used in the synthesis of phenothiazine derivatives that can inhibit protein farnesyltransferase molecules and some that show anti-proliferative activity.<br>References Baciu-Atudosie, L. et al.: Bioorg. Med. Chem. Lett., 22, 6896 (2012); Kawano, S. et al.: Biosci. Biotech. Biochem., 75, 1055 (2011);<br></p>

<p>Applications 1,4-Dihydroxy-2-butanone (cas# 140-86-3) is a useful research chemical.<br></p>

<p>Applications Cyclododecanone is a general chemical reagent used in organic synthesis.<br>References Hu, Y. et al.: Org. Biomol. Chem., 14, 3022 (2016);<br></p>

<p>Applications 5-[1-Hydroxy-2-(2,4,5-trifluorophenyl)ethylidene]-2,2-dimethyl-1,3-dioxane-4,6-dione is an impurity of the DPP-IV inhibitor Sitagliptin (S491000).<br>References Ye, F. et al.: Hech. Huax., 18, 767 (2010); Ahn, J.H, et al.: Bioorg. Med. Chem. Lett., 17, 2622 (2007);<br></p>

<p>Applications 2-Hexanone is used in various organic chemical syntheses. It is used in the synthesis of (+/-)-monomorine. It is also used in the preparation of alcohols by transfer hydrogenation of ketones.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Le, T. et al.: Tetrahedron Lett., 53, 5660 (2012); Ikhile, M. et al.: Tetrahedron Lett., 53, 4925 (2012);<br></p>

<p>Applications 3,​3-​Dimethyl-​2,​4-​pentanedione is used in asymmetric hydrosilation of ketones.<br>References Kuwano, R., et al.: Bull. Chem. Soc. Jpn., 73, 485 (2000).<br></p>

<p>Stability Moisture Sensitive<br>Applications 4,7-dimethyl-1,3-dihydro-2-benzofuran-1,3-dione (cas# 5463-50-3) is a useful research chemical.<br></p>

<p>Applications iso-Butyl Vinyl Ketone is a major component in the secretion of Iporangaia pustulosa and Neosadocus maximus.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Rocha, D.F., et. al. J. Nat. Prod., 74, 658 (2011)<br></p>

<p>Please enquire for more information about 2-(Chloromethyl)-3-(4-fluorophenyl)quinazolin-4(3H)-one including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 1-Phenyl-4-hexyn-3-one including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>p-Mentha-8-thiol-3-one is a stabilizer that can be used in the synthesis of agathosma and other terpenes. It is also used as a mass spectrometric standard for the identification of stereoisomers. p-Mentha-8-thiol-3-one has been shown to have antibacterial effects against gram positive bacteria, including methicillin resistant Staphylococcus aureus (MRSA). This compound can be used in vitro to study the interactions between cytochrome P450 enzymes, lipid matrix and terpene compounds. In addition, it has been shown to work as a gas sensor, where it reacts with sodium sulfide to produce hydrogen sulfide gas.</p>

<p>4-Fluorophenylacetone is a phenylacetic acid derivative that inhibits the 5-HT2 receptors. It has been shown to have inhibitory activities against dopamine and serotonin by acting as an agonist at the receptor. 4-Fluorophenylacetone also binds to nucleophilic sites on proteins, which may lead to inhibition of protein synthesis. This product has been used in molecular modeling studies and has been shown to be an amine with a phosphate group that can form a stable bond with other molecules. Brevibacterium sp. strain P7 was used as a model system for this study and it was found that 4-fluorophenylacetone inhibited the growth of this bacterium by binding to the enzyme RNA polymerase, preventing transcription and replication.</p>

<p>Please enquire for more information about 8-[(2-Hydroxyethyl)(methyl)amino]-1,3,9-trimethyl-3,9-dihydro-1H-purine-2,6-dione including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 17,21Dihydroxy-16beta-methylpregna-1,4,9(11)-triene-3,20-dione including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 5alpha-Cholestane-3,7-dione including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>1-Pentyl-1H-indole-2,3-dione is a synthetic cannabinoid that is used as a recreational drug. It has been shown to be thermally labile and can decompose at high temperatures. 1-Pentyl-1H-indole-2,3-dione is an acidic compound with a melting point of 79°C. The compound is also oxidant and therefore can react with other compounds to create new substances. This reaction can be accelerated by light or heat, which may result in the formation of hazardous products such as naphthalene.</p>

<p>Please enquire for more information about 5-Chloro-2-hydroxy-2-methoxycarbonyl-1-indanone including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>2-Amino-2-(2-chlorophenyl)cyclohexan-1-one is an anesthetic drug that belongs to the group of ketamine. It is a chiral compound and has been shown to have central nervous system depressant effects, which are more pronounced than those of ketamine. This drug also affects the cardiovascular system and can cause respiratory depression. 2-Amino-2-(2-chlorophenyl)cyclohexan-1-one has been shown to be metabolized in humans by cytochrome P450 (CYP3A4). It may potentiate the effect of drugs that induce CYP3A4 activity such as erythromycin, rifampin, and phenobarbital.<br> 2-Amino-2-(2-chlorophenyl)cyclohexan-1-one is not active against MRSA or methicillin resistant pseudomonas aeruginosa (MR</p>

<p>(3,5-Dimethoxy-4-hydroxyphenyl)acetone is a phenolic compound that is used as a calibration standard in the analysis of tannins. It has been shown to have a catalytic effect on the oxidation of oleic acid and linoleic acid in the presence of peroxides. The addition of (3,5-dimethoxy-4-hydroxyphenyl)acetone to an oil or fat emulsion at room temperature leads to an increase in the viscosity of the emulsion. This compound can be found in many plants, such as tea and coffee beans, cocoa beans, and red wine grapes.</p>

<p>Please enquire for more information about 1-(1-Methyl-1H-indazol-3-yl)ethanone including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>11alpha-Methylandrostan-17beta-ol-3-one is a pharmacological agent that belongs to the group of androgens. It is an oral preparation and has been used in the treatment of infectious diseases, autoimmune diseases, and metabolic disorders. It has also been used as a matrix effect control in biological samples. The biological effects of 11alpha-Methylandrostan-17beta-ol-3-one are mediated by its direct action on cells or through conversion to testosterone or dihydrotestosterone (DHT). These effects include increasing protein synthesis, promoting bone formation, lowering cholesterol levels, stimulating the production of red blood cells, and decreasing fat deposition. The main side effects are acne vulgaris, male pattern baldness, prostate enlargement, increased risk for prostate cancer, and increased risk for developing breast cancer.</p>

<p>5-Hydroxyquinolin-2(1H)-one is a chalcone that can be synthesized from 2,5-dihydroxybenzaldehyde and quinoline. It is a bacteriostatic agent that inhibits bacterial growth by binding to the 50S ribosomal subunit, blocking the formation of an antibiotic-substrate complex with the enzyme cell wall synthesis that is required for cell wall biosynthesis, inhibiting protein synthesis and cell division. 5-Hydroxyquinolin-2(1H)-one has shown activity against methicillin resistant Staphylococcus aureus (MRSA) and methicillin resistant Enterococcus faecium. 5-Hydroxyquinolin-2(1H)-one also represses the expression of DNA topoisomerase II genes, which may be associated with its inhibitory effects on bacterial growth.</p>

<p>Please enquire for more information about 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)isoindolin-1-one including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 2-(Chloromethyl)-3-(2-methylphenyl)quinazolin-4(3H)-one including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>2-Amino-1-(4-fluorophenyl)-1-propanone (Fluoroamphetamine) is a chemical that binds to the serotonin transporter, which is responsible for the reuptake of serotonin into the presynaptic neuron. Fluoroamphetamine has been shown to lower empathy and increase feelings of reward in animals. This drug has no significant effect on dopamine and noradrenaline levels but does cause an increase in metabolic acidosis. Fluoroamphetamine is most often used by analytical laboratories as a synthetic intermediate, but it can also be used as a strategy to develop specific antidotes against serotonin blockers. Fluoroamphetamine's health effects are similar to those of amphetamine with regards to cardiovascular risks and addictive potential.</p>

<p>3-(2-Bromoacetyl)-2H-chromen-2-one is a compound that has been shown to inhibit the growth of human liver cancer cells and has been used in the treatment of some cancers. 3-(2-Bromoacetyl)-2H-chromen-2-one is a nucleophile, which reacts with electrophiles, such as 2Nal, to form an intermediate covalent bond. The reaction mechanism for this process involves a nucleophilic substitution reaction, where one atom (the nucleophile) attacks another atom (the electrophile) from the side opposite its electron cloud. This process results in the formation of a covalent bond between the two atoms and the release of water. 3-(2-Bromoacetyl)-2H-chromen-2one was found to be effective against Streptococcus faecalis and other bacteria after being tested in vitro with these organisms. In addition to being</p>

<p>10b-Hydroxyestr-4-ene-3,17-dione (10bOHE1) is a reactive molecule that can undergo nucleophilic substitution reactions with nucleophiles. It has a strong odor and binds to odorant receptors in the nose. 10bOHE1 is an analog of estrone and interacts with aromatase enzymes, which are involved in the biosynthesis of estrogens. This molecule can be used as an inhibitor for aromatase enzymes in the biosensors for estrogen activity.</p>

<p>Please enquire for more information about 1-[3-Chloro-5-(trifluoromethyl)phenyl]ethanone including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about (16a)-21-(Acetyloxy)-16-methyl-pregna-1,4,9(11)-triene-3,20-dione including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>7,8-Dimethylbenzo[g]pteridine-2,4(1H,3H)-dione is a stable complex that has been shown to connect with riboflavin. It has been used as a fluorescence probe for the detection of receptor molecules in biological samples. 7,8-Dimethylbenzo[g]pteridine-2,4(1H,3H)-dione was synthesized through the reaction of 2-(4-bromophenyl)pyridine and 2-aminoethanol. The compound has also been studied for its ability to prevent cardiac infarcts by stabilizing blood platelets and reducing the risk of thrombosis.</p>

<p>Please enquire for more information about 9-[(5-Amino-1,3,4-thiadiazol-2-yl)methyl]-1,3-dimethyl-3,9-dihydro-1H-purine-2,6-dione including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>3-Hydroxy-2-butanone is a reactive, fatty acid with the chemical formula CH3(CH2)4COH. It is a methyl ketone and an important intermediate in the synthesis of other organic compounds. 3-Hydroxy-2-butanone can be produced by corynebacterium glutamicum through the addition of air to a mixture of 2-butanol and malonic acid. This compound has inhibitory properties against wild type strains of corynebacterium glutamicum and caproic acid production by tissue culture cells. The mechanism for this inhibition is not yet known, but it may be due to its ability to alter the biochemical properties of corynebacterium glutamicum.</p>

<p>Please enquire for more information about 5alpha-Pregnan-20beta-Ol-3-one including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>