
Ketones
Found 18871 products of "Ketones"
Efavirenz
CAS:Efavirenz is a non-nucleoside-based reverse transcriptase inhibitor (NNRTI) of the reverse transcriptase of HIV-1. It inhibits the viral enzyme reverse transcriptase by binding to its active site. In certain cell culture assays, efavirenz showed great efficiency when inhibiting wild-type HIV-1 replication with values of inhibition constant Ki between 2.97 to 17.60 mM in single mutation enzymes and 26.05 to 56.50 nM in double mutation. In the treatment of HIV, efavirenz has been studied in combination with emtricitabine and tenofovir disoproxil fumarate for ease of administration in some clinical studies. Recent in vitro cell studies indicated efavirenz is a potential treatment for pancreatic, prostate and triple-negative breast cancers due to its cytotoxicity against cancer cells, with an EC50 of 31.5 μM.Formula:C14H9ClF3NO2Purity:Min. 95%Color and Shape:PowderMolecular weight:315.68 g/mol6-Oxo boldione
CAS:Controlled Product6-Oxo boldione is an aromatase inhibitor that inhibits the conversion of testosterone to estradiol and has been shown to be effective in inhibiting the growth of bacteria such as Typhimurium. 6-Oxo boldione has been shown to inhibit the growth of estrogen-sensitive breast cancer cells in vitro. It also has a dose-dependent effect on rat liver microsomes, with a greater inhibition at high doses. This drug may be metabolized by modification of its side chain or by biotransformation. 6-Oxo boldione is not active against other enzymes such as cytochrome P450 or glutathione S-transferases.Formula:C19H22O3Purity:Min. 95%Color and Shape:PowderMolecular weight:298.38 g/mol3-(4-chlorophenyl)spiro[1,3-thiazolidine-2,3'-indoline]-4,7-dione
CAS:Please enquire for more information about 3-(4-chlorophenyl)spiro[1,3-thiazolidine-2,3'-indoline]-4,7-dione including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormula:C16H11ClN2O2SPurity:Min. 95%Color and Shape:PowderMolecular weight:330.79 g/mol7-Amino-2-(4-methoxyphenyl)[1,2,4]triazolo[1,5-a]pyrimidin-5(4H)-one
CAS:7-Amino-2-(4-methoxyphenyl)[1,2,4]triazolo[1,5-a]pyrimidin-5(4H)-one is a fine chemical that belongs to the category of versatile building blocks. It can be used as a reagent for research purposes and as a speciality chemical for the production of complex compounds. This compound is also an important building block for the synthesis of compounds with high quality and useful scaffolds.Formula:C12H11N5O2Purity:Min. 95%Color and Shape:PowderMolecular weight:257.25 g/mol3-(4-ethoxyphenyl)-5-indol-3-yl-1H,4H,5H-1,2-diazin-6-one
CAS:Please enquire for more information about 3-(4-ethoxyphenyl)-5-indol-3-yl-1H,4H,5H-1,2-diazin-6-one including the price, delivery time and more detailed product information at the technical inquiry form on this pagePurity:Min. 95%3-(4-(tert-butyl)phenyl)-5-indol-3-yl-1H,4H,5H-1,2-diazin-6-one
CAS:Please enquire for more information about 3-(4-(tert-butyl)phenyl)-5-indol-3-yl-1H,4H,5H-1,2-diazin-6-one including the price, delivery time and more detailed product information at the technical inquiry form on this pagePurity:Min. 95%p-Nitrobenzyl 6-(1'-hydroxyethyl)-azabicyclo(3.2.0)heptane-3,7-dione-2-carboxylate
CAS:p-Nitrobenzyl 6-(1'-hydroxyethyl)-azabicyclo(3.2.0)heptane-3,7-dione-2-carboxylate is a drug substance that is used in the manufacture of carbapenem antibiotics. It can be detected by a chloride ion chromatographic method, and the detection limit is 0.5 mg/L in the presence of zinc powder as a modifier. This material is used to prepare carbapenems using an analytical method that includes reaction monitoring by optical rotation, diastereomer chromatography, and transfer.Formula:C16H16N2O7Purity:Min. 95%Color and Shape:PowderMolecular weight:348.31 g/mol(1R)-(-)-2-Azabicyclo[2.2.1]hept-5-en-3-one
CAS:(1R)-(-)-2-Azabicyclo[2.2.1]hept-5-en-3-one is a carbocyclic nucleoside that has been used as a flow rate standard to measure the rate of liquid chromatography. It is an organic solvent, which has been shown to have kinetic properties in the ring opening of lactams and the hydrolysis of esters. (1R)-(-)-2-Azabicyclo[2.2.1]hept-5-en-3-one can be synthesized by reacting with a cocatalyst and a reaction time of less than 5 minutes at room temperature in a high performance liquid chromatography method or by liquid chromatography with preparative methods.br>br> (1R)-(-)-2-Azabicyclo[2.2.1]hept-5-en-3-one is used as a binding agent forFormula:C6H7NOPurity:Min. 98 Area-%Color and Shape:White PowderMolecular weight:109.13 g/mol3β,5-Dihydroxy-15β,16β-methylene-5β-androst-6-en-17-one
CAS:Controlled Product3b,5-Dihydroxy-15b,16b-methylene-5b-androst-6-en-17-one is a steroid hormone that has been shown to have antihypertensive properties. It has been shown to reduce the production of angiotensin II by inhibiting the enzyme angiotensin converting enzyme (ACE). 3b,5-Dihydroxy-15b,16b-methylene-5b-androst-6-en 17 one has also been shown to be a potent inhibitor of the enzyme 3beta hydroxysteroid dehydrogenase type 1 (3betaHSD1) and 5alpha reductase type 2 (5alphaRD2), which are enzymes that convert cortisone to cortisol and dihydrotestosterone to testosterone respectively. These effects on steroidogenesis may account for its observed antihypertensive activity.
Formula:C20H28O3Purity:Min. 95%Color and Shape:PowderMolecular weight:316.43 g/molThiazolidine-2,4-dione
CAS:Thiazolidine-2,4-dione (THZ) is a drug that has been shown to be an orally active, anti-inflammatory agent with postprandial blood glucose lowering properties. It inhibits the nuclear factor kappa B (NF-κB) binding activity and suppresses inflammation in vitro and in vivo. THZ also has hypoglycemic effects and may be used as an oral hypoglycemic agent for the treatment of diabetes mellitus type 2. THZ is not active against bowel disease or atherosclerosis. It interacts with other drugs, such as statins, which reduce its hypoglycemic effects. This drug also intercalates into DNA and binds to response elements related to inflammation and insulin signalling pathways.Formula:C3H3NO2SPurity:Min. 89.0%Color and Shape:PowderMolecular weight:117.13 g/mol3-(tert-butyl)-2-phenylindeno[3,2-c]pyrazol-4-one
CAS:Please enquire for more information about 3-(tert-butyl)-2-phenylindeno[3,2-c]pyrazol-4-one including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormula:C20H18N2OPurity:Min. 95%Color and Shape:PowderMolecular weight:302.37 g/mol2-Norbornanone
CAS:2-Norbornanone is a chemical compound that has been shown to be toxic to animals. It is used as a solvent and an intermediate in the manufacture of other chemicals. 2-Norbornanone is soluble in water and its toxicity depends on the pH of the solution. The toxicity of this compound increases with increasing acidity. The sodium salt of 2-norbornanone has no effect on the proton concentration at any pH level, while the acetate extract has a slight effect at low pH levels. This suggests that hydrogen bonding interactions are important for 2-norbornanone's toxicity.Formula:C7H10OPurity:Min. 95%Color and Shape:PowderMolecular weight:110.15 g/mol2-Methyl-1,2-benzisothiazolin-3-one
CAS:2-Methyl-1,2-benzisothiazolin-3-one (MBIT) is a water soluble microbiocide which is active against bacteria, yeasts and moulds and has potential applications as a preservative in paints, sealants and coatings. Similar compounds (BIT, MIT) have found use as preservatives in detergents and cleaning products due to their relative stability in solution and compatibility with enzymes.
Formula:C8H7NOSPurity:Min. 96 Area-%Color and Shape:White Off-White PowderMolecular weight:165.21 g/mol4-(Methylamino)-1-(3-pyridyl)-1-butanone dihydrochloride
CAS:4-(Methylamino)-1-(3-pyridyl)-1-butanone dihydrochloride (4-MBA) is a natural product that has been shown to have anti-cancer properties in vitro and in vivo. It inhibits the growth of cancer cells by inhibiting DNA synthesis and inducing apoptosis, as well as by inhibiting the production of certain proteins. 4-MBA has been shown to be effective against strains of Escherichia coli and Salmonella typhimurium. This compound is found in honeybush tea, Aspalathus linearis, and other plants, but is not present in humans or animals. 4-MBA has also been shown to inhibit nicotine metabolism in humans and rats.Formula:C10H16Cl2N2OPurity:Min. 95%Color and Shape:SolidMolecular weight:251.15 g/mol4-Aza-3-chromanone
CAS:4-Aza-3-chromanone is a naturally occurring compound that has been shown to have antimicrobial properties. 4-Aza-3-chromanone inhibits the synthesis of fatty acids by inhibiting the enzyme stearoyl (CoA) desaturase. This leads to a decrease in the production of cellular membrane phospholipids, which are necessary for cell growth. 4-Aza-3-chromanone also has an inhibitory effect on the ability of colorectal adenocarcinoma cells to grow and form colonies, which indicates that it may have anticancer properties. 4-Aza-3-chromanone binds to a target enzyme, which causes a change in its conformation and prevents it from catalyzing reactions with substrates. The binding site of 4-aza-3 chromanone is hydrophobic, which means it has hydrogen bonding interactions with functional groups like amino acids or carboxyl groups.
Formula:C8H7NO2Purity:Min. 95%Color and Shape:PowderMolecular weight:149.15 g/mol(5-Bromo-4-methoxyphenyl)acetone
CAS:5-Bromo-4-methoxyphenyl)acetone (BMA) is a versatile building block that is used in the production of fine chemicals, research chemicals, and reagents. It has been shown to be a useful scaffold for the synthesis of complex compounds. BMA is also an intermediate for the production of other chemicals. This chemical has been shown to have high quality with a wide range of uses as a reaction component or useful scaffold.Formula:C10H11BrO2Purity:Min. 95%Molecular weight:243.1 g/mol4-Pregnen-17alpha,20alpha,21-triol-3-one
CAS:Controlled Product4-Pregnen-17alpha,20alpha,21-triol-3-one (4PT) is a versatile building block that can be used in the synthesis of complex compounds. It has been used as a reagent and speciality chemical in research chemicals and as an intermediate for pharmaceuticals and other organic syntheses. 4PT also has been shown to have high quality with a reaction component and scaffold for organic synthesis.Formula:C21H32O4Purity:Min. 95%Color and Shape:PowderMolecular weight:348.48 g/mol(2-Methoxyphenyl)acetone oxime
CAS:2-Methoxyphenyl)acetone oxime is a versatile building block that can be used in the synthesis of complex compounds. It is a colourless crystalline solid with a melting point of 138°C and a boiling point of 188°C. This compound has been assigned CAS No. 43021-97-2 and is soluble in water, ethanol, acetone, benzene, chloroform, ether and ethyl acetate. The chemical structure for this compound is shown below:
Formula:C10H13NO2Purity:Min. 95%Color and Shape:PowderMolecular weight:179.22 g/mol19-Hydroxy-androstene-4-ene-3,17-dione
CAS:Controlled Product19-hydroxy-androstene-4-ene-3,17-dione is a metabolite of androstenedione that has been shown to have inhibitory effects on prostate cancer cells. This compound binds to the plasma membrane of these cells, leading to changes in its structure and function. 19-hydoxy-androstene-4-ene-3,17-dione has also been shown to have an inhibitory effect on human chorionic gonadotropin (HCG) and oestrone production by inhibiting the release of luteinizing hormone from the pituitary gland. This compound also inhibits the activity of protein kinase C (PKC), which is important for cell signaling. 19 hydroxyandrostene 4, 17 dione inhibits tissue culture reactions that rely on PKC as well as other enzymes involved in this process.Formula:C19H26O3Purity:Min. 98 Area-%Color and Shape:Off-White PowderMolecular weight:302.41 g/mol4-Methyl-2(5H)-furanone
CAS:4-Methyl-2(5H)-furanone is an isomeric compound that can be isolated from various plant sources including isoprene, chalcones, and other plant extracts. It has been shown to inhibit the formation of dental plaque and the growth of oral bacteria in a functional group study. 4-Methyl-2(5H)-furanone is also known as a chalcone and has been shown to have antibacterial properties. This chemical reaction can be used as an alternative to chlorhexidine for the treatment of dental plaque.Formula:C5H6O2Purity:Min. 95%Color and Shape:Clear LiquidMolecular weight:98.1 g/mol
