Ketones

Please enquire for more information about 1-(4-Fluoro-3-(trifluoromethyl)phenyl)-2,6,6-trimethyl-5,6,7-trihydroindol-4-one including the price, delivery time and more detailed product information at the technical inquiry form on this page

2-Acetamido-6-formylpteridin-4-one is a reductive amination product of folic acid. It is a stable compound and has been shown to be useful in the treatment of human diseases such as cancer, Alzheimer's disease, and Parkinson's disease. The reductive amination reaction produces formyl groups that can be acetylated or alkylated to produce stable compounds with different properties. This compound also reacts with glutamic acid to produce an amide.

Please enquire for more information about 2,2-dimethyl-5-(((2-phenylethyl)amino)methylene)-1,3-dioxane-4,6-dione including the price, delivery time and more detailed product information at the technical inquiry form on this page

Dibenzylideneacetone (DBA) is a pro-apoptotic protein that binds to DNA and targets the mitochondria. It has been shown to have potent antitumor activity, as well as other biological properties. DBA binds to the cytosolic calcium ion with a coordination geometry of square planar, which may be due to its similarity to sodium. This compound also interacts with leishmania parasites and mitochondrial membrane potential.

1-(3-Aminopropyl)pyridin-2(1H)-one HCl is a fine chemical that belongs to the group of heterocyclic compounds. It is a versatile building block that can be used as an intermediate or a scaffold in chemical synthesis. 1-(3-Aminopropyl)pyridin-2(1H)-one HCl is soluble in water and has been shown to react with a variety of other compounds, including amines, alcohols, thiols, and phenols. This compound also has high quality and can be used for research purposes.

Please enquire for more information about 5-(((2-(3,4-dimethoxyphenyl)ethyl)amino)methylene)-2,2-dimethyl-1,3-dioxane-4,6-dione including the price, delivery time and more detailed product information at the technical inquiry form on this page

Efavirenz is a non-nucleoside-based reverse transcriptase inhibitor (NNRTI) of the reverse transcriptase of HIV-1. It inhibits the viral enzyme reverse transcriptase by binding to its active site. In certain cell culture assays, efavirenz showed great efficiency when inhibiting wild-type HIV-1 replication with values of inhibition constant Ki between 2.97 to 17.60 mM in single mutation enzymes and 26.05 to 56.50 nM in double mutation. In the treatment of HIV, efavirenz has been studied in combination with emtricitabine and tenofovir disoproxil fumarate for ease of administration in some clinical studies. Recent in vitro cell studies indicated efavirenz is a potential treatment for pancreatic, prostate and triple-negative breast cancers due to its cytotoxicity against cancer cells, with an EC50 of 31.5 μM.

6-Fluoro-1,3,4,5-tetrahydro-3-[4-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]-1H-- 1,2,3-triazol-1yl]-1-(2trifluoroethyl)-2H-1benzazepin-2one (6FTH) is an anticancer drug that belongs to the class of benzothiazole derivatives. It has been shown to have potent antiangiogenic and antiproliferative properties in preclinical studies. 6FTH has been shown to be effective against colon cancer and breast cancer cells in vitro. It also inhibits the growth of squamous cell carcinoma cells by downregulating the expression of proteins involved in tumorigenesis. The compound has been found to be safe when used as an adjuvant to a combination therapy containing cisplatin

Please enquire for more information about 5,5-dimethyl-2-(((3-nitrophenyl)amino)methylene)cyclohexane-1,3-dione including the price, delivery time and more detailed product information at the technical inquiry form on this page

3',4'-Dihydroxyphenylacetone (DOPA) is a metabolite of dopamine that is produced in the brain and kidneys. DOPA has been shown to have pharmacological properties, but its function as an endogenous neurotransmitter has not been confirmed. DOPA is also a precursor for the synthesis of melanin, which is found in skin cells. The detection of DOPA in urine samples can be used to diagnose Parkinson's disease or other conditions characterized by low levels of dopamine. The enzyme glutamate dehydrogenase converts DOPA into 3-methoxytyramine, which can be detected in urine samples using chromatographic methods. 3',4'-Dihydroxyphenylacetone may be measured in the blood plasma of patients with bacterial infections and urinary tract infections. A detectable concentration of this metabolite could indicate that the body is making use of an alternate pathway for synthesizing amines.

2-(2-Butyl)-4-{4-[4-(4-methyloxy-phenyl)-piperazin-1-yl]-phenyl}-2,4-dihydro-[1,2,4]-triazol-3-one (ITZ) is an antifungal drug that inhibits the synthesis of ergosterol. It is used in the treatment of systemic fungal infections such as candidiasis and cryptococcosis. ITZ is a metabolite of itraconazole and fluconazole. The presence of impurities in ITZ can be detected by liquid chromatography with a diode array detector or a fluorescence detector. An antiinfective drug product should be bioequivalent to the reference product and have comparable levels of impurities. Chromatograms are used to identify peaks on a graph and measure their height (area under the curve) to determine how much of each substance is present in the sample.

(6alpha,17beta)-6-Fluoro-17-Hydroxyandrost-4-En-3-One is an androgen that has both agonistic and antagonistic effects on nuclear receptors. It activates the androgen receptor and is equipotent with testosterone. This drug also inhibits the estrogen receptor, but does not bind to the progesterone receptor. This synthetic agent is used for treating hypogonadism in males due to castration or aging and prostate cancer.

3-[(4-Fluorophenyl)amino]cyclohex-2-en-1-one is a drug that has been shown to have both inotropic and chronotropic effects on the heart. It also has a hypotensive activity, which may be due to its ability to reduce peripheral resistance by blocking alpha 1 receptors. 3-[(4-Fluorophenyl)amino]cyclohex-2-en-1-one is an anaesthetic agent with the potential for use in surgical procedures. The structural similarity of 3-[(4-Fluorophenyl)amino]cyclohex-2-en-1-one to acrylonitrile suggests that this drug may be toxic to the heart, as acrylonitrile is a known cardiotoxin.

Eupatilin is a flavonoid compound, which is derived from the Artemisia species. This plant-based source has been traditionally used in various medicinal applications across different cultures. Eupatilin’s mode of action involves inhibition of pro-inflammatory cytokines and modulation of signaling pathways associated with inflammation, such as the NF-kB pathway. Additionally, it has been found to possess antioxidant activities, which further contributes to its therapeutic potential.

Please enquire for more information about 2-(benzo[3,4-d]1,3-dioxolen-5-ylmethylene)indane-1,3-dione including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 11-(tert-butyl)spiro[1,2,3-trihydroquinazoline-2,4'-cyclohexane]-4-one including the price, delivery time and more detailed product information at the technical inquiry form on this page

(8S,10S,11S,13S,14S,17S)-9-Fluoro-11-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-2,6,7,8,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-one (fluorometholone) is a corticosteroid that is used in the treatment of asthma and other respiratory diseases. Fluorometholone has been shown to have strong antiinflammatory activity and inhibit the production of inflammatory cytokines. It also has mineralocorticoid activity and can be used to treat adrenal insufficiency. This drug has potent potencies structurally similar to glucocorticoids and mineralocorticoids.

1-(4-Hydroxyphenyl)-2-phenyl-1-butanone is a versatile building block that is used in the synthesis of many complex compounds. It has been used as a reagent or speciality chemical and can be used to synthesize a wide range of organic compounds. The compound also exhibits high quality and can be used as an intermediate in the synthesis of pharmaceuticals, herbicides, pesticides, and other research chemicals. 1-(4-Hydroxyphenyl)-2-phenyl-1-butanone is also a useful scaffold for the synthesis of natural products such as alkaloids, terpenes, and other research chemicals.

Please enquire for more information about 2-Bromo-1-(1H-indol-3-yl)propan-1-one including the price, delivery time and more detailed product information at the technical inquiry form on this page