Amides

<p>Parathyroid hormone-related protein (PTHrP) is a peptide hormone produced by the parathyroid gland that functions as a phosphatase, inhibiting alkaline phosphatase. It also has an inhibitory effect on osteoclastic bone resorption and stimulates osteoblastic bone formation. PTHrP has been shown to be useful in treating osteoporosis and Paget's disease. It also has been used in conjunction with dexamethasone to treat patients with malignancies of the head and neck. PTHrP is an inhibitor of protein kinase A and phosphodiesterases, which are enzymes that regulate cellular processes such as proliferation and differentiation.</p>

<p>Antho-RFamide Pyr-Gly-Arg-Phe-NH2 is an acidic amino acid. It has been shown to be a precursor of dopamine β-hydroxylase, which is a key enzyme in the synthesis of epinephrine and norepinephrine. This compound has a diameter of 0.8 nm, and it's been observed in cnidarians and multicellular animals. The biological function of Antho-RFamide Pyr-Gly-Arg-Phe-NH2 is not yet known, but it has been sequenced and identified as fatty acid with a sequence that is identical to serotonin. Analysis shows that this molecule contains an acidic environment with an alkaline pH.</p>

N,N'-Bis(2-mercaptoethyl)isophthalamide is a peptide hormone that belongs to the group of imines. It is the active substance in fulminant hepatitis and has been used as a diagnostic agent. It has been shown to increase serum alanine levels and decrease intracellular glutathione levels in the brain. N,N'-Bis(2-mercaptoethyl)isophthalamide has also been used as a pharmaceutical formulation for treatment of liver disease. The dosage ranges from 10 mg/kg to 20 mg/kg body weight per day.

<p>Dynorphin A (1-11) amide trifluoroacetate salt is a modified form of the opioid peptide dynorphin, which is a natural ligand for kappa-opioid receptors. It has affinity for the surface receptors and can be used to study the modifications that occur in cell function. Dynorphin A (1-11) amide trifluoroacetate salt has been shown to decrease cell function when it interacts with these surface receptors, which are found in brain homogenates and other tissues. Dynorphin A (1-11) amide trifluoroacetate salt also has an effect on brain cells, which may be due to its ability to alter conformational changes in proteins by binding to them. This can lead to alterations in the structure of certain enzymes or receptor proteins.</p>

<p>Ceramide is a fatty acid that is an important component of cell membranes. It has been shown to inhibit the activity of enzymes such as phospholipase A2 and lipoxygenase, which are involved in inflammatory reactions. Ceramide can also be used to diagnose infectious diseases, such as tuberculosis and malaria. The diagnostic procedure involves measuring the enzyme activities of ceramidase and lysosomal sphingomyelinase with the help of a radioactive substrate. This can be done by extracting tissue from mammalian cells or by drawing blood samples from patients. In addition, ceramide may be associated with insulin resistance and cancer.</p>

<p>Please enquire for more information about TRAP-14 amide trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about (Nle 8·18,Tyr34)-pTH (1-34) amide (bovine) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>N,N-Bis(2-hydroxyethyl)dodecanamide is a surfactant that is used in the treatment of wastewater. It has been shown to be effective at removing p-hydroxybenzoic acid from water and at reducing the concentration of this compound in the environment. N,N-Bis(2-hydroxyethyl)dodecanamide also has antimicrobial properties and synergizes with other antimicrobial agents to provide a more potent effect than when it is used alone. This surfactant has been shown to have an effect on congestive heart failure by blocking the action of angiotensin II receptors.</p>

<p>Please enquire for more information about beta-Casomorphin (1-2) amide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>4-Methylsalicylamide is a chemical compound that belongs to the class of isonicotinic amides. It is a potent anti-inflammatory agent with minimal inhibitory concentration (MIC) values of 4 µg/mL for gram-positive bacteria and 8 µg/mL for gram-negative bacteria. This compound has been shown to be effective against methicillin-resistant Staphylococcus aureus (MRSA) and Clostridium perfringens, although is not active against acid-fast bacteria such as Mycobacterium tuberculosis or Mycobacterium avium complex. 4-Methylsalicylamide has been shown to have an inhibitory effect on ring-opening, which may be due to its ability to acetylate mitochondrial membranes, altering the membrane potential. The molecular modeling studies also showed that 4MSAM binds at the same site as antibiotics such as penicillin and erythromycin in bacterial ribos</p>

<p>Please enquire for more information about Amyloid P Component (33-38) amide trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about (Tyr34)-pTH (7-34) amide (bovine) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Dermorphin is a peptide that is derived from the proenkephalin gene. It is an opioid analgesic and has been shown to be effective in the treatment of hernias. Dermorphin has also been shown to inhibit platelet aggregation and blood coagulation, making it an antithrombotic therapy. The structure of dermorphin has been determined using a hydroxy group as the reactive site for synthesis and molecular modelling techniques. Dermorphin has also been shown to have an active oxygen species selectivity index (a measure of antioxidant activity) higher than those of other drugs in its class, which makes it suitable for use as a sealant in abdominal surgery.</p>

<p>Please enquire for more information about PAR-3 (1-6) amide (mouse) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>PAR-2 agonist is a synthetic peptide that activates PAR-2. It binds to PAR-2 receptors, which are present in the mesenteric vasculature and in various other tissues. Activation of PAR-2 leads to an increase in intracellular calcium concentration, activation of protein kinase C, cytosolic calcium ion release, phosphorylation of myosin light chain, muscle cell proliferation, transcription and translation initiation, and increased production of vasoactive intestinal peptide. This drug also has anti-inflammatory effects and stimulates epidermal growth factor (EGF) and thrombin receptor expression as well as growth factor production.</p>

<p>Intermediate in the synthesis of vildagliptin</p>

<p>Please enquire for more information about Propionyl-Amyloid b-Protein (31-34) amide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Salicylamide is a drug that is used as an analgesic, antipyretic, and anti-inflammatory agent. It is also used to treat bowel disease, including ulcerative colitis and Crohn's disease. Salicylamide has been shown to inhibit the activity of enzymes such as cyclooxygenase-2 (COX-2) and 5-lipoxygenase (5-LOX), which are responsible for the production of inflammatory mediators. Salicylamide also inhibits copper chloride induced synchronous fluorescence in rat colon cells. Salicylamide also binds to human serum albumin and other nitrogen atoms, which can be measured using chemiluminescence methods. Salicylamide may also have properties that make it useful for the detection of cancerous tumors in the colon. Salicylamide can be detected using electrochemical impedance spectroscopy by measuring its resistance at different frequencies when a voltage is applied across a cell containing sal</p>

<p>N-[4-(2-Bromoacetyl)phenyl]methanesulfonamide is a chiral biocatalytic agent, which is synthesized by chemoenzymatic or enzymatic reactions. It has been used in enantioselective synthesis of 4-aminoacetophenone and as an antiarrhythmic agent. This compound is not active against bacterial infections.</p>

<p>Please enquire for more information about Antho-RPamide III·HCl Pyr-Val-Lys-Leu-Tyr-Arg-Pro-NH2·HCl including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Gastric Inhibitory Polypeptide (1-30) amide (porcine) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about (Nle 8·21,Tyr34)-pTH (1-34) amide (rat) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>H-Tyr-L-1,2,3,4-tetrahydroisoquinoline-3-carboxamide·HCl is a monoclinic crystalline compound. It has a molecular weight of 607.14 and contains the dipeptide Tyr-Lys in its structure. H-Tyr-L-1,2,3,4-tetrahydroisoquinoline-3-carboxamide·HCl crystallizes in the P21/c space group and has an asymmetric unit cell with dimensions a=8.851 Å, b=7.965 Å and c=5.98 Å. This compound has been shown to have antibacterial properties against methicillin resistant Staphylococcus aureus (MRSA) isolates and Clostridium perfringens strains by inhibiting bacterial protein synthesis through inhibition of peptidyl transferase activity.</p>

<p>Please enquire for more information about Amyloid b-Protein (1-40) amide trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Clopamide is a diuretic drug that belongs to the group of protein genes. It is used in the treatment of chronic heart failure, low-density lipoprotein cholesterol and infectious diseases. Clopamide has been shown to increase the glomerular filtration rate by inhibiting the sodium citrate enzyme, which is involved in the formation of urine from blood plasma. This drug also reduces blood pressure by blocking angiotensin II receptors on vascular smooth muscle cells. Clopamide does not have any significant interactions with other drugs, although caution should be exercised when using it with cardiac drugs due to its effects on blood pressure.</p>

<p>Please enquire for more information about (Asn10,Leu11,D-Trp12)-pTH-Related Protein (7-34) amide (human, mouse, rat) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Cecropin A (1-8)-Melittin (1-18) amide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Dermorphin is a neuropeptide that has been shown to reduce cortisol levels in badgers and has been shown to have biological activity in vitro. Dermorphin also has a number of pharmacokinetic properties, including water solubility, lipid solubility, and oral bioavailability. The drug binds to δ receptors and inhibits the enzyme activities of rat liver microsomes. Dermorphin is used as an analgesic for bowel disease, such as inflammatory bowel disease or hypogaea. Dermorphin has antinociceptive properties (pain-relieving).</p>

<p>Growth hormone-releasing factor (GRF) is a peptide fragment of amino acids 1–2 from GHRH (growth hormone-releasing hormone). This 1-29 region is the shortest fully functional fragment of GHRH. GRF is also known as sermorelin. Sermorelin binds to the growth hormone-releasing hormone receptor (GHRH-R), and acts as a surrogate for GHRH, causing growth hormone secretion.human: H-YADAIFTNSYRKVLGQLSARKLLQDIMSR-NH2rat:        H-HADAIFTSSYRR I LGQLYARKLLHEIMNR-NH2</p>

<p>2-Methyl-N-phenyl-5,6-dihydro-1,4-oxathiine-3-carboxamide is a signal molecule that has antimicrobial activity. It inhibits the proliferation of cells and is used as an antifungal agent. 2,5,6-Trimethyloxathiinium ion has been shown to induce apoptosis in human leukemia cells and inhibit the growth of erythrocytes infected with Plasmodium falciparum. This compound also inhibits wild type strains of bacteria and fungi and can be used as a natural fungicide. 2,5,6-Trimethyloxathiinium ion has been found to be effective in treating autoimmune diseases such as diabetes mellitus type II, which may be due to its ability to regulate glucose metabolism and suppress inflammatory responses.</p>

<p>Please enquire for more information about Mca-Amyloid beta/A4 Protein Precursor770 (667-676)-Lys(Dnp)-Arg-Arg amide trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about (Nle 8·18,Tyr34)-pTH (7-34) amide (bovine) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about cAMP-Dependent Protein Kinase Inhibitor-a (5-22) amide (human, mouse, rabbit, rat) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Galanin Message Associated Peptide (44-59) amide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about PAR-2 (6-1) amide (human) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

Please enquire for more information about (Phe1,Ser2,Tyr6)-PAR-1 (1-6) amide (human) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page

<p>Please enquire for more information about (D-Arg6,Asn10)-MCH (6-16) amide (human, mouse, rat) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Benzamidine is a benzamidase inhibitor that competitively binds to bacterial enzymes such as metalloendopeptidases and matrix metalloproteinases. It inhibits the degradation of collagen, resulting in a higher concentration of soluble extract. This drug also has an effect on spermatozoa, which may be due to its ability to inhibit bacterial enzymes that are involved with uptake and preload. Benzamidine has been shown to have a pH optimum of 8-9 and is most active at this pH range.</p>

<p>Please enquire for more information about (D-Arg2)-Dermorphin (1-4) amide trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>PAR-2 (6-1) amide is a proteolytic enzyme that is activated by inflammatory stimuli. It has been shown to be a major contributor to the pathogenesis of inflammatory bowel disease, and is found in neurons, the bowel, and pancreatic acinar cells. PAR-2 (6-1) amide activates proteases such as trypsin and chymotrypsin and also functions as an antimicrobial peptide. Activation of PAR-2 (6-1) amide leads to the cleavage of proteins at specific sites on their amino acid chains. This cleavage can lead to changes in protein conformation or function. PAR-2 (6-1) amide has been shown to increase endothelial cell proliferation and inhibit bacterial growth, but does not have any effect on cultured normal human skin fibroblasts.</p>

<p>N-Hydroxy-2-phenyl-acetamide is a metalloprotease inhibitor that binds to the active site of the enzyme, thereby preventing it from binding with its natural substrate. This drug has been shown to inhibit the production of TNF-α in mice with autoimmune diseases and may be able to inhibit other proinflammatory mediators. N-Hydroxy-2-phenyl-acetamide has been shown to bind to a water molecule and an aliphatic hydrocarbon in order to form a hydrogen bond. This coordination complex inhibits the activity of matrix metalloproteinases, which are enzymes that break down collagen, elastin, and other proteins in the extracellular matrix. N-Hydroxy-2-phenyl-acetamide is not active against acid complexes or tnfα.</p>

<p>2,2-Dimethylpropionamide is a synthetic chemical that has been shown to have cytotoxic and biochemical properties. It has been tested on leukemia cells (K562) and has been shown to inhibit the bcr-abl kinase. 2,2-Dimethylpropionamide has also been shown to inhibit the production of amide radicals in human serum under constant pressure. The structure of this compound was solved using X-ray diffraction data.</p>

<p>4-Biphenylac-Cys(Me)-D-Arg-Phe-(2-phenylethyl)amide is a tetrapeptide that has been shown to have antihypertensive properties. This drug binds to the regulatory proteins of the renin angiotensin system and blocks the production of angiotensin II, which decreases blood pressure. 4-Biphenylac-Cys(Me)-D-Arg-Phe-(2-phenylethyl)amide has also shown to be an effective treatment for skin care products, especially those used for inflammatory skin diseases. 4-Biphenylac-Cys(Me)-D-Arg-Phe-(2-phenylethyl)amide has been shown to be a potent inhibitor of serine proteases and can inhibit cellular proliferation and induce apoptosis in cancer cells.</p>

<p>Please enquire for more information about Mca-(Asn670,Leu671)-Amyloid beta/A4 Protein Precursor770 (667-676)-Lys(Dnp)-Arg-Arg amide trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>2-Amino-N-[2-(2,5-dimethoxyphenyl)-2-hydroxyethyl]-acetamide is a drug that has been used to treat a variety of diseases and conditions. It is an alpha adrenergic agonist that works by stimulating the alpha receptors in the body, which increase blood pressure and improve blood flow. This drug also has significant effects on energy metabolism, including the production of ATP. 2-Amino-N-[2-(2,5-dimethoxyphenyl)-2-hydroxyethyl]-acetamide is used to treat patients with congestive heart failure who are taking low doses of midodrine hydrochloride or nonsteroidal antiinflammatory drugs.</p>

<p>(2R)-2-Aminopropanamide is a chemical compound that is classified as an amide. It has been shown to inhibit bacterial growth and induce apoptosis in mammalian cells, but not in bacteria. This drug has a number of hydrogen bonding interactions with the carbonyl group and amide functional groups and can bind to affinity ligands with hydrogen bonding interactions. (2R)-2-Aminopropanamide inhibits the activity of enzymes that are involved in the synthesis of d-alanine, which is a precursor for protein synthesis. It also inhibits the enzyme glutamine synthase, which plays a key role in building up nitrogen reserves in bacteria. The drug binds to DNA by forming hydrogen bonds with the phosphate backbone and intercalates into double-stranded DNA by forming van der Waals interactions with base pairs.</p>

<p>Acetyl-L-leucine amide is a drug used to treat symptoms of depression in geriatric patients. It is an amide form of acetyl-L-leucine, which is an amino acid that plays a role in the synthesis of proteins and lipids. Acetyl-L-leucine amide has been shown to have antidepressant effects in geriatric patients with mild to moderate depression. This drug can be used as part of a combination therapy for infectious diseases, such as tuberculosis, when there is no infection or when resistance to other antibiotics has occurred. Acetyl-L-leucine amide has also been shown to be effective against cervical cancer and breast cancer cells. The synthesis of this drug involves two steps: first, reacting L-leucine with acetyl chloride; second, reacting the product with aqueous ammonia solution.</p>

<p>Please enquire for more information about Acetyl-Neurotrophin Receptor (368-381) amide (human) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>N-Methyl-4-oxo-4,5-dihydropyridine-3-carboxamide is a fine chemical that can be used as a reagent or intermediate. It is a versatile building block that can be used in the production of useful scaffolds or useful intermediates. This compound has been shown to react with many different types of chemicals, including alcohols and amines. N-Methyl-4-oxo-4,5-dihydropyridine-3-carboxamide can also be used as a reaction component in the synthesis of diverse compounds.</p>

LymnaDFamide-1 is a neuropeptide that belongs to the family of c-terminal peptides. It is a dipeptide with a sequence of L-Pro-Tyr-Asp-Arg-Ile-Ser-Asn-Ser-Ala-Phe. This peptide was found in the nervous system of invertebrates, where it is believed to play an important role in the regulation of neurotransmitter release. In mammals, LymnaDFamide has been detected in the brain and in the gallbladder. It may be involved in regulating feeding behavior and gastric motility.