Carboxylic Acids

<p>Please enquire for more information about (1H-Benzo[d][1,2,3]triazol-5-yl)boronic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>3a,21-Dihydroxy-5a-pregnane-11,20-dione 21-acetate is a short-acting intravenous anaesthetic that is used in surgical procedures. It has been shown to have antinociceptive properties and can be used as a potent analgesic. 3a,21-Dihydroxy-5a-pregnane-11,20-dione 21-acetate binds to the alpha1 adrenergic receptor and blocks the release of noradrenaline from nerve terminals in the brain. This prevents the activation of neurons in the spinal cord that transmit pain signals to the brain. The drug also inhibits the action of gamma aminobutyric acid on neurones and increases levels of cortisol concentration in blood plasma. The mechanism by which 3a,21 -dihydroxy 5a pregnane 11,20 dione 21 acetate produces its anaesthetic effects has not yet been elucidated.</p>

<p>4-Mercaptobutyric acid is a 3-mercaptopropionic acid, which is an intermediate in the biosynthesis of fatty acids. It is a chemical ligation agent that can be used for the synthesis of polymers and pharmaceuticals. 4-Mercaptobutyric acid can also be used to produce butyrolactone, which has been shown to have anticonvulsant properties. The chemical's photochemical properties make it useful for the production of dyes and fluorescent compounds. 4-Mercaptobutyric acid has been shown to inhibit fatty acid synthesis in Sprague-Dawley rats. The compound also possesses anti-inflammatory properties, which may be due to its ability to inhibit the release of prostaglandin E2 (PGE2) from cells.</p>

<p>Please enquire for more information about 20-Dehydro cholesterol 3-acetate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 8-Ethyl-1,3,4,9-tetrahydro-1-(1-methylethyl)pyrano[3,4-b]indole-1-acetic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Native Melan-A (26-35) decapeptide derives from the melanocyte lineage-specific protein Melan-A/MART-1, which is expressed in almost 75-100% of primary and metastatic melanomas.<br>The region 26-35 of Melan-A protein acts as an antigenic peptide that is recognized by CD8+ tumor-reactive cytolytic T lymphocytes (CTLs) for designing antigen-specific cancer vaccines1. It has been shown that CD8+ Melan-A-specific CTLs isolated from melanoma patients efficiently lyse the Melan-A-expressing HLA-A*0201+ melanoma cell line. However, CTLs preferentially recognize the Melan-A (26-35) peptide as compared with the Melan-A (27-35) peptide. Moreover, the Melan-A (26-35) A27L analog (ELAGIGILTV) has a higher binding affinity to HLA-A*0201 than the native Melan-A (26-35) peptide (EAAGIGILTV), and consequently displays more potent antigenicity and immunogenicity.<br>It has been reported that the concentration of Melan-A (26-35) A27L analog required to obtain 50% of maximal antigenic activity (EC50) is 0.01nM, whereas that of the native Melan-A (26-35) peptide is 0.25nM1. Therefore, the relative activity of Melan-A (26-35) A27L analog is 25 fold higher than that of the native Melan-A (26-35) peptide.<br>Furthermore, functional competition assay has shown that the concentration of Melan-A (26-35) A27L analog required to achieve 50% inhibition (IC50) of tumor lysis is 2nM, which is 10 fold lower than that of the native Melan-A (26-35) peptide. Regarding peptide stability in human serum, the half-lifes (t1/2) of the native Melan-A (26-35) peptide and the A27L analog are quite similar (45 and 40min, respectively) as measured by HPLC-ESI-MS, but much higher than that of the Melan-A (27-35) nonapeptide (5min).</p>

<p>5-Bromo-1H-indole-2-carboxylic acid methyl ester is a drug that belongs to the class of carboxylates. It has been shown to inhibit the growth of tumor cells in vitro and in vivo. The antitumor activity of this compound may be due to its ability to stabilize planar indole moieties, which are cytotoxic. 5-Bromo-1H-indole-2-carboxylic acid methyl ester interacts with other molecules through intermolecular interactions and can form an indole ring system that has a trifluoromethyl group and a carboxylate group in its structure.</p>

<p>N-Aminocarbonyl-L-aspartic acid (NACD) is a molecule that is found in urine samples. It can be used as a biomarker to detect cancer, HIV infection, and many other diseases. The presence of NACD has been correlated with the development of acidosis, which is characterized by an increase in the pH of body fluids. The following are a few examples of how this product might be described on an eCommerce site: Rifapentine is an anti-tuberculosis drug that belongs to the class of rifamycins. It is the most active of the rifamycins for the treatment of tuberculosis. Rifapentine inhibits bacterial growth by binding to DNA-dependent RNA polymerase, thereby preventing transcription and replication. The high frequency of human activity has been shown using a patch-clamp technique on human erythrocytes. This active form is metabolized through</p>

<p>Please enquire for more information about (2S)-2-(1H-Tetrazol-1-yl)propanoic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Ziconotide acetate is a polymer conjugate of ziconotide and goserelin acetate. It is used to treat severe chronic pain in patients who have not responded to other treatments, such as opioids or local anesthetics. Ziconotide acetate is administered by injection into the intrathecal space, where it acts on nerve cells in the dorsal horn of the spinal cord. The drug is slowly released from the polymer conjugate over time, which effectively reduces its irritant effects. It also has low solubility in water, which helps reduce its rate of clearance from the body. The active substances in this drug are ziconotide and goserelin acetate, both of which have been shown to be effective for treating chronic pain. Ziconotide acetate has also been shown to cause a decrease in blood levels of cholesterol and lipoproteins, although this effect may be due to goserelin acetate rather than ziconotide itself.</p>

<p>3-Keto-7a,12a-dihydroxy-5a-cholanic acid is a steroid hormone that is synthesized from cholesterol. It is one of the major hormones involved in the regulation of the menstrual cycle and ovulation. The levels of this hormone increase during ovulation, with maximal concentration occurring at midcycle. 3-Keto-7a,12a-dihydroxy-5a-cholanic acid is converted by enzymes into estradiol and testosterone. 3-Keto-7a,12a-dihydroxy-5a-cholanic acid may also be involved in regulating peptide hormones and pheromones.</p>

<p>Please enquire for more information about 4-Chloro-3,5-difluorobenzoic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>3,3-Difluoropentanedioic Acid is a reagent that is used in organic chemistry. It can be hydrolyzed to give 3,3-difluoro-1,2-propanediol. This chemical reacts with dithianes to give 1,2-dithiane and quantitatively produces 3-fluoro-1,2-propanediol. It is an ester of 3,3-difluoropentanedioic acid and has been shown to have antiinflammatory properties in rats.</p>

<p>Please enquire for more information about 3-Maleimidopropionic acid hydrazonium trifluoroacetate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Dimethyl 1-[2-(1H-indol-3-yl)ethyl]-2,5-dimethyl-1H-pyrrole-3,4-dicarboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about D-Glyceric acid calcium dihydrate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Ethylcyclobutanecarboxylate is an organic compound that is used as a drug for the treatment of cancer. It has been shown to inhibit cholesterol ester transfer and has been used in the treatment of pancreatitis, autoimmune diseases, dyslipoproteinemia, and inflammatory diseases. This drug has been shown to reduce insulin resistance and can be used as a treatment for diabetes-associated complications. Ethylcyclobutanecarboxylate is also metabolized into a pharmacologically active form by cb2 receptor. The biological samples that have been studied include plasma and urine; however, it can also be detected in other types of tissue such as brain, stomach, and kidney.</p>

<p>Please enquire for more information about tert-Butyl 6-(aminomethyl)-1,4-oxazepane-4-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Ethacrynic acid L-cysteine adduct (EAC) is a non-competitive inhibitor of phosphatases. It is a β-unsaturated ketone that has been shown to inhibit the phosphatase activity of pepsin and other enzymes. EAC binds to glutathione, forming an inactive covalent bond. The glutathione conjugate is inactivated by incubation with aminopyrine and pepsin, which degrades the glutathione moiety. This leads to the formation of a phosphatase inhibitor that is catalytic and competitive in nature. EAC can be used as a reagent for cell culture media or tissue sections, where it inhibits the activity of phosphatases that might interfere with certain enzymatic reactions.</p>

<p>6-Bromohexanoic acid is a fatty acid that has been shown to be an effective agent for the treatment of cancer. It is used in gene therapy to inhibit the growth of cancer cells by binding to and then activating transcription factors. 6-Bromohexanoic acid can also be used as a chemotherapeutic agent and has been shown to cause apoptosis in monoclonal antibody-treated cells. 6-Bromohexanoic acid has pharmacokinetic properties that are similar to those of other fatty acids. The reaction solution was found to have high chemical stability, which may be due to the presence of nitrogen atoms. This reaction solution was found to adsorb onto the surface of monoclonal antibodies and cell culture, altering their properties.</p>