Carboxylic Acids

<p>N-Acetyl-L-arginine dihydrate (N-Ac-L-arg-OH) is one of the guanidino compounds found elevated in the serum of a hemodialyzed renal insufficient (uremic)</p>

<p>DSPS (Dioctadecanoylphosphatidylserine) is an important phospholipid membrane component, plays a key role in cell cycle signaling, specifically in apoptosis.</p>

<p>NADH disodium salt hydrate, a reduced NAD form, donates electrons and gets oxidized to NAD+ in reduction reactions.</p>

<p>Diethyl oxalpropionate, a slightly soluble beta-keto acid derivative, is weakly acidic, mainly found in the cytoplasm.</p>

<p>D-Galacturonic acid hydrate is used in the synthesis of N-(D-galacturonoyl) amino acids and dipeptides.</p>

<p>N-Isovaleroylglycine, a leucine catabolism byproduct, is an acyl glycine elevated in some metabolic disorders and indicates IVA when accumulated.</p>

<p>12-Hydroxydodecanoic acid (12-hydroxylauric acid) is the substrate of the human glutathione-dependent formaldehyde dehydrogenase.</p>

<p>Aminoadipic acid, a lysine metabolism intermediate, inhibits kynurenic acid production and antagonizes NMDA receptor activity.</p>

<p>Diaminopimelic acid or DAPA is a lysine-like amino acid derivative that is a key component of the bacterial cell wall.</p>

<p>(R)-5-Oxopyrrolidine-2-carboxylic acid (D-Pyroglutamic acid) is a cyclic derivative of glutamic acid, physiologically present in mammalian tissues.</p>

<p>NSC 90469 (Diiodothyronine) is an iodinated thyronine hormone that regulates gene activity affecting processes such as homeostasis and insulin resistance.</p>

2-Ketoglutaric acid Sodium (AKG) is a key molecule in the TCA cycle.

<p>2-Hydroxy-4-methoxybenzoic acid (2-Hydroxy-p-anisic Acid) is a predicted metabolite generated by BioTransformer1.</p>

<p>Stability Light Sensitive<br>Applications Thiacetic Acid is a commonly used reagent in organic synthesis for the introduction of thiol groups in molecules.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Chapman, J.H. et al.: J. Chem. Soc., 579 (1950); Hoque, A., et al.: Bioorg. Med. Chem. Lett., 22, 6770 (2012)<br></p>

<p>Applications Ethyl 4-Phenylacetoacetate is a useful synthetic intermediate. It is used to prepare pyrazolone derivatives as antiprion compounds. It is also used to prepare pyrrolinylaminopyrimidine analogs as inhibitors of AP-1 and NF-κB mediated gene expression.<br>References Kimata, A., et al.: J. Med. Chem., 50, 5053 (2007); Palanki, M., et al.: Bioorg. Med. Chme. Lett., 12, 2573 (2002)<br></p>

<p>Applications 4-carbamoylfuran-2-carboxylic acid (cas# 1315367-95-3) is a useful research chemical.<br></p>

<p>Applications Fendizoic Acid is a reagent in the synthesis of fluorinated polyphthalazinone ethers containing perfluorophenylene moieties.<br>References Lu, Z., et al.: J. Polym. Sci. A1, 42, 925 (2004)<br></p>

<p>Applications (2E)-3-Phenyl-2-propenoic Acid is used in the synthesis of amides and esters through coupling reactions involving carboxylic acids and amines. Also used in the N-methylation of amides and O-methylation of carboxylic acids.<br>References Kunishima, M. et al.: Tetrahedron, 55, 13159 (1999); Xia, Q. et al.: Org. Lett., 15, 3326 (2013);<br></p>

<p>Applications Used as a general reagent in acylation reactions. A byproduct formed in treated waters, and found in marine life.<br> E0<br>References Zuckermann, R.N. et al.; J. Am. Chem. Soc., 115, 10646 (1992); Bull, R., et al.: Toxicol. Appl. Pharmacol., 182, 55 (2002), Mitch, W., et al.: Water Sci. Technol., 2, 191 (2002),<br></p>

<p>Applications N-(2,6-Diisopropylphenylcarbamoylmethyl)iminodiacetic Acid (cas# 65717-97-7) is a compound useful in organic synthesis.<br></p>

<p>Stability Hygroscopic<br>Applications Used in the manufacturing of L-tryptophan by enzymic reaction.<br>References Franke, L., et al.: J. Med. Chem., 48, 6997 (2005), Fox, T., et al.: Curr. Top Med. Chem., 6, 1579 (2006),<br></p>

<p>Applications Phenyl N-​(2-​Chloro-​4-​hydroxyphenyl)​carbamate is a reagent used in the prepartion of quinoline-carboxamide compounds including Lenvatinib (L329400), an orally active inhibitor of multiple receptor tyrosine kinases including VEGF, FGF and SCF receptors.<br>References Wang, N. et al.: Faming Zhuanli Shenqing (2017), CN 106632033 A 20170510.<br></p>

<p>Stability Air Sensitive, Hygroscopic<br>Applications 3-Mercaptolactic Acid is used in the phosphorylation and acetylation of histone H2B.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Chiang, K. et al.: ChemBioChem., 10, 2182 (2009);<br></p>

<p>Applications Octyl 3-Octyloxiraneoctanoic Acid (cas# 106-84-3) is a compound useful in organic synthesis.<br></p>

<p>Applications N-Undecylbenzenesulfonic Acid is an anionic surfactant.<br>References Mottaleb, M. A.: Anal. Sci., 15, 1137 (1999), Kolb, M., et al.: LaborPraxis, 22, 56 (1998); Ferrer D., et al.: Tenside, Surfact., Det., 34, 278 (1997)<br></p>

<p>Applications Reagent used in labelled pyrimidine and purine synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Das, S., et al.: J. Med. Chem., 52, 5937 (2009), Kim, K., et al.: Bioorg. Med. Chem. Lett., 19, 5225 (2009),<br></p>

<p>Applications N,N'-Bis(2,6-diisopropylphenyl)-1,6,7,12-tetraphenoxy-3,4,9,10-perylenetetracarboxylic Diimide has applications in the photosensors and optical detectors.<br>References Wang, Shaojun, et al.: ACS Photonics, 5(6), 2478-2485 (2018);Wang, Hanlin, et al.: Adv. Mat., 29(32), n/a. (2017)<br></p>

<p>Applications 3,5-Di-tert-butyl-4-hydroxybenzoic acid<br></p>

<p>Applications Cyclohexanecarboxylic acid<br></p>

<p>Applications (1-acetyl-2,3-dihydro-1H-indol-5-yl)boronic acid (cas# 905971-97-3) is a useful research chemical.<br></p>

<p>Applications 6-(Aminocarbonyl)-3-cyclohexene-1-carboxylic Acid is a useful building block for organic synthesis.<br></p>

<p>Impurity Oxybutynin USP Related Compound A<br>Applications An intermediate in the synthesis of oxybutynin (O868525). Oxybutynin USP Related Compound A.<br></p>

<p>Applications Hydrazine acetate (cas# 7335-65-1) is a useful research chemical.<br></p>

<p>Applications Ethyl Cyano(hydroxyimino)acetate is used in peptide synthesis and has shown to suppress racemiztion, has high coupling efficiency in both solution and solid phase synthesis and is a non-explosive alternative to 1-hydroxybenzotriazole (HOBt) and 1-hydroxy-7-azabenzotriazole (HOAt).<br>References Khattab, S.N.: Bull. Chem. Soc. Jpn., 83, 1374 (2010)<br></p>

<p>Applications 11-MERCAPTOUNDECANOIC ACID (cas# 71310-21-9) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 17-Hydroxy-3,11-dioxo-androsta-1,4-diene-17β-carboxylic Acid is an intermediate used to prepare (11β,​17α)​-17-​[(Ethoxycarbonyl)​oxy]​-​11-​hydroxy-​3-​oxo-​androsta-​1,​4-​diene-​17-​carboxylic acid (E890570) which is a derivative of Loteprednol Etabonate (L471400), an ophthalmic corticosteroid.<br>References Alberth, M., et al.: J. Biopharm.Sci., 2, 115 (1991), Bodor, N., et al.: Pharm. Res., 9, 1275 (1992), Bartlett, J.D., et al.: J. Ocul. Pharmacol., 9, 157 (1993)<br></p>

<p>Applications 2,2-Diphenylpentanoic Acid (cas# 841-32-7) is a compound useful in organic synthesis.<br></p>

<p>Applications DL-2-aminobutyric acid<br></p>

<p>Stability Volatile<br>Applications Methyl Acetate is used as an organic chemical solvent for a multitude of organic processes. Also used in the production of biodiesel.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Xu, Y. et al.: J. mol. Cat., 32, 241 (2005); Ogino, H. et al.: J. Biosci. Bioeng., 89, 451 (2000);<br></p>

<p>Applications 1-Cyclohexenylcarboxylic Acid is a reagent used in the synthesis and optimization of small-molecule HIV-1 entry inhibitors. Also used in the stereoselective synthesis of diazabicyclic β-lactams for antimicrobial activity.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Tuyishime, M. et al.: Bioorg. Med. Chem. Lett., 24, 5439 (2014); Zhang, S. et al.: J. Org. Chem., 81, 956 (2016);<br></p>

<p>Applications (S)-2-Amino-4-[(3-aminopropyl)amino]-butanoic Acid is used in the reaction of carboxynorspermidine decarboxylase of Vibrio alginolyticus.<br>References Nakao, H., et al.: J. Gen. Microbiol. 136, 1699-704 (1990)<br></p>

<p>Applications 6-Chlorohexanoic Acid is used as the starting material in the synthesis of 2,6-Dichloro-N-(2,6-dimethylphenyl)hexanamide (D434225); an impurity of the local anesthetic Levobupivacaine (B689546). 6-Chlorohexanoic Acid is also used as a reagent in the synthesis of novel types of polyester glycodendrimers as potential inhibitors of urinary tract infections.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Tullar, B., et al.: J. Med. Chem., 14, 891 (1971); Schmidt, A., et al.: Pharm. Res., 22, 2121 (2005); Twibanire, J.K., et al.: New J. Chem., 39, 4115 (2015)<br></p>

<p>Applications 2,3-Dihydroxypropanoic acid(20% in water) (cas# 473-81-4) is a useful research chemical.<br></p>

<p>Applications Boric Acid, Pinacol Ester was a useful reagent in the study of hydrogen peroxide inducible DNA croslsinking agents as anticancer prodrugs.<br>References Kuang, Y., et al.: J. Am. Chem. Soc., 133, 19278 (2011);<br></p>

<p>Applications trans-3-(2-Chloro-3,3,3-trifluoro-1-propenyl)-2,2-dimethyl-cyclopropanecarboxylic Acid is a reagent used in the synthesis of indanyl insecticides.<br></p>

<p>Applications Boric Acid is a common chemical component in insecticides, specifically for flea erradication. Also has the properties of an effective flame retardant.<br>References Hinkle, N. et al.: J. Med. Entomol., 32, 424 (1995); Dogan, M. et al.: Polym. Degrad. Stab., 99, 12 (2014);<br></p>

<p>Applications Citraconic Acid (cas# 498-23-7) is a useful research chemical.<br></p>

<p>Applications Dithiocarbamate complexes serve as hosts for the specific binding of various metal cations.<br>References Bourson, J., et al.: J. Phys. Chem., 97, 4552 (1993), Lai, S., et al.: Inorg. Chem., 38, 4262 (1999),<br></p>

<p>Applications 3-(Phenylthio)acrylic Acid (cas# 63413-91-2) is a useful research chemical.<br></p>