6-membered Rings

Applications 5-Nitro-1-benzofuran is a chemical reagent used in the synthesis of internal alkynes. Also used in the preparation of anti-oxidants quinolines.
References Lu, L. et al.: Eur. J. Org. Chem., 2013, 1644 (2013); Kuzmin, V. et al.: Russ. Chem. Bull., 57, 2405 (2008);

Applications 3,5-dihydro-2H-1,5-benzothiazepin-4-one (cas# 53454-43-6) is a useful research chemical.

Applications 6-Bromo-8-fluoro-2,4-dihydro-1,4-benzoxazin-3-one is a reactant in preparation of benzoxazinone derivatives as potent and selective nonsteroidal mineralcorticoid receptor antagonists.
References Hasui, T., et al.: J. Med. Chem., 54, 8616 (2011);

Applications 2-CYCLOPENTYL-2-PHENYLACETIC ACID (cas# 3900-93-4) is a useful research chemical.

Applications 5-Ethyl-2-fluorophenylboronic acid

Applications 1,6-Anhydro-β-L-gulopyranose is an intermediate used in the synthesis of Troxacitabine (T805580), which is a nucleoside analogue with potential anticancer activity. Troxacitabine have been studied in patients with refractory lymphoproliferative diseases.
References Robak, T., et al.: Curr. Med. Chem., 18, 638 (2011); Kornblau, S.M., et al.: Clin. Cancer. Res., 16, 3721 (2010);

Applications 5-[3-(Trifluoromethoxy)phenyl-2-Furancarboxylic Acid is the structural analogue of 5-[2-(Trifluoromethoxy)phenyl]-2-furancarboxylic Acid (T790925), a reactant used in the preparation of (phenyl)-N-[(mercapto)(pyrrolyl)triazolyl]furancarboxamide and (phenoxy)-N-[(mercapto)(pyrrolyl)triazolyl]acetamide derivatives as herbicides.
References Xue, S., Lu, C.: Youji Huaxue, 28, 1083 (2008)

Applications 2,6-DIMETHYLBENZOQUINONE (cas# 527-61-7) is a useful research chemical.

Applications tert-Butyl (5-Chloro-2-fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)carbamate is used as a reactant in the synthesis of BRAF-kinase inhibitors.
References Repik, Alexey E., et al.: PCT Int. Appl., WO 2017146604 A1 20170831 (2017)

Applications 4-Hydroxyphenylacetone (cas# 770-39-8) is a useful research chemical.

Applications 6-Aminobenzothiazole is a useful intermediate in synthesizing N-phenyl-substituted and di-substituted guanidinyl benzothiazole derivatives. These derivatives act as antimicrobial and antioxidant agents.
References Mahesh, B., et al.: Res. Chem. Intermed., 42, 6195 (2016)

Applications trans-2-(Chloromethyl)cyclohexanemethanol is an impurity of Lurasidone Hydrochloride (L474920), an antipsychotic used for treatment of schizophrenia.
References Ishiyama, T., et al.: Eur. J. Pharmacol., 572, 160 (2007); Cole, P., et al.: Drugs of the Fut., 33, 316 (2008)

Applications 3,4-Bis(isobutoxycarbonyl)benzoic Acid is a useful reagent in organic synthesis.

Applications 3-Amino-4-(carboxymethyl)benzoic acid

Stability Store in freezer at -20°C
Applications A synthetic intermediate

Applications Can be used in the preparation of pyrrolylphenylsulfonates as dopamine D3 antagonists as well as in the preparation of substituted amidothiophene derivatives for use as 11-β-HSD1 inhibitors.

Applications Used in the preparation of herbicides and pesticides intermediates.

Applications 3,5-Dibenzyloxybenzyl alcohol (cas# 24131-31-5) is a useful research chemical.

Applications O-Benzylmetaraminol is an impurity of M225565.

Applications 4-hydroxy-2-nitrobenzoic acid (cas# 74230-08-3) is a useful research chemical.

Applications 2,3-Dimethylphenylacetic Acid (cas# 30981-98-7) is a compound useful in organic synthesis.

Applications A versatile phosphitylating agent.
References Perich, J.W., et al.: Synthesis, 142 (1988)

Applications Methyl 4-(trifluoromethyl)benzoate

Applications Methyl 5-chloro-2-nitrobenzoate

Applications α-Bromo-2,3,4,5,6-pentafluorotoluene, can be used as an organic fluorinated building blocks for chemical synthesis.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications 2-(3-Butynyloxy)tetrahydro-2H-pyran is used as a reagent in the synthesis of Phomoidride D, a bridged, polycyclic, natural compound that has the ability to inhibit squalene synthase and can be used as an antihypercholesterolemic agent. 2-(3-Butynyloxy)tetrahydro-2H-pyran is also used as a reagent to prepare Rugulactone, a natural compound that is isolated from Cryptocarya rugulosa.
References Allais, F., et al.: Synthesis, 2010, 2787 (2010); Biller, S., et al.: Curr. Pharm. Des., 2, 1 (1996); Chen, C., et al.: J. Am. Chem. Soc., 122, 7424 (2000); Murphy, G., et al.: J. Org. Chem., 78, 477 (2013)

Applications Methyl 4-Ethyloxybenzoate acts as a reagent used in the synthesis of novel inhibitors targeting HDAC8 from schistosoma mansoni for treatment of Scistosomiasis.
References Heimburg, T., et al.: J. Med. Chem., 59, 2423 (2016)

Applications O-((Perfluorophenyl)methyl)hydroxylamine Hydrochloride functions as one of the substances used in the identification of stable cytotoxic factors in extracts of cigarette smoke and in the pharmacological characterization of their cytotoxicity.
References Noya Y., et al.: Toxicology, 314, 1 (2013)

Applications 4-Ethylsulfonylphenylboronic acid is used in the discovery of small molecular RIP1 kinase inhibitors for the treatment of pathologies associated with necroptosis.
References Harris, P. A,, et al.: ACS Med. Chem. Lett., 4, 1238 (2013)

Applications sec-Butylbenzene is used as the starting material in the synthesis of 2-(p-sec-Butylphenyl)propionic Acid (B692720); an impurity of Ibuprofen (I140000). sec-Butylbenzene is also used as the sole carbon and energy source for certain Pseudomonas bacteria strains (1,2). Environmental pollutant.Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References 1. Baggi, G. et al.: Biochem J. 1972 Mar;126(5):1091-7.2. Yang, S. et al.: Environ Technol. 2016;37(9):1045-53.

Applications Methyl 3-hydroxy-4,5-dimethoxybenzoate (cas# 83011-43-2) is a useful research chemical.

Applications An intermediate for the preparation of (+/-)-Taxifolin.

Applications Heptylbenzene is a useful synthetic intermediate. It is used in zirconia and titania based stationary phase capillary HTLC, to separate alkyl benzene derivatives using an acetonitrile-water eluent. It can also be used to prepare 3-chloropyridine-stabilized palladium imidazolylidene complexes as catalysts for Suzuki and Negishi cross-coupling reactions.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Kephart, T., et al.: Anal. Chim. Acta., 414, 71 (2000); O’Brien, C., et al.: Chem. Eur. J., 12, 4743 (2006)

Applications 3-(4-Hydroxyphenyl)propionitrile (cas# 17362-17-3) is a compound useful in organic synthesis.