6-membered Rings

Applications Methyl 4-Acetylbenzoate is used in the preparation of trisubstituted pyrazoles as novel hepatitis C virus entry inhibitors.
References Hwang, J.Y., et al.: Bioorg. Med. Chem. Lett., 23, 6467 (2013); Simmonds, P., et al.: Hepatology, 42, 962 (2005)

Applications A useful synthetic intermediate.

Applications 4-Ethylbenzoic acid

Applications N1,N2-Bis(4-hydroxy-2,6-dimethylphenyl)ethanediamide is an intermediate used in the synthesis of 1-Naphthol-d7 (d6 Major) (N367993), which is the isotope labelled analog of 1-Naphthol (N367990), a compound commonly used in the manufacturing of dyes, intermediates, synthetic perfumes.

Applications 4-(2-Amino-3,3-dimethyl-1-oxobutyl)benzonitrile hydrochloride is used as a reagent to synthesize phenyloxobutanylpyridinylpiperazinecarboxamide derivatives, compounds that have TRPA1 receptor antagonistic properties.
References Svensson, M. & Weigelt, D. Preparation of Phenyloxobutanylpyridinylpiperazinecarboxamide Derivatives for Use as TRPA1 Receptor Antagonist. PCT Int. Appl. 2012050512. Apr 19, 2012.

Applications Phenyl 4-Hydroxybenzoate is a substance for the production of stable exenatide preparations for treating diabetes and obesity. Investigation of drug partition property in artificial sebum for the targeted delivery of therapeutic agent into the hair and sebaceous follicles. In vitro and molecular docking studies on the side chains of parabens as modulators of antiandrogenic activities.
References Valiveti, S., et al.: Int. J. Pharm.; Zhong, H., et al.: From Faming Zhuanli Shenqing (2009), CN 101366692 A 20090218; Ding, K., et al.: Env. Sci. Technol., 51, 6452 (2017)

Applications 4-phenyl-2,3-dihydroquinazolin-2-one (cas# 23441-75-0) is a useful research chemical.

Applications N-Benzylethylenediamine can be used to develop imidazoline derivatives as ligands for dopamine D4 receptor. It is also a reagent for enantioselective synthesis of epoxides and piperazinones.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Mammoli, V., et al.: ChemMedChem 11, 1819 (2016); Meninno, S., et al.: Org. Lett. 17, 4348 (2015)

Applications N-(4-amino-2-chlorophenyl)-5-chloro-2-hydroxybenzamide (cas# 10558-45-9) is a useful research chemical.

Stability Moisture Sensitive
Applications Tributylphenyltin acts as a reagent for the synthetic preparation of tetrahydroisoquinolines and SAR as potential HIV-1 antivirals.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Swidorski, J. J., et al.: Bioorg. Med. Chem. Lett., 26, 160 (2016)

Applications 1,1-Dimethoxycyclohexane (cas# 933-40-4) is a useful research chemical.

Stability Air Sensitive
Applications 2,3,4,6-tetrahydroxy-5H-benzo[7]annulen-5-one (cas# 569-77-7) is a useful research chemical.

Applications 5-Amino-2-chlorobenzenesulfonamide (cas# 2015-19-2) is a compound useful in organic synthesis.
References Somers, F., et al.: Pharm. Pharmacol. Commun., 6, 89 (2000), D'Ambrosio, K., et al.: J. Med. Chem., 51, 3230 (2008),

Applications 2-PHENYLNICOTINIC ACID (cas# 33421-39-5) is a useful research chemical.

Applications Intermediate in the preparation of various antidepressants and protein kinase inhibitors.
References Kojima, T., et al.: Chem. Pharm. Bull., 33, 3766 (1985), Jinbo, Y., et al.: J. Med. Chem., 37, 2791 (1994),

Applications Mono and dibasic phosphate esters are anionic surfactants which have the main feature of the stability in alkaline conditions over other surfactants. They have a wide range of properties including outstanding wetting, emulsification, lubrication, coupling activity and detergency.
References Ramirez, F., et al.: Tetrahedron, 35, 1581 (1979);

Applications b-Phenylethyl Furoate (cas# 7149-32-8) is a useful research chemical.

Applications 3,3-DIPHENYLPROPANOL (cas# 20017-67-8) is a useful research chemical.

Applications Intermediate in the production of Cyclophosphamide metabolites.
References Hashizume, H., et al.: Chem. Pharm. Bull., 42, 2097 (1994), Wu, L., et al.: Bioorg. Med. Chem., 15, 7434 (2007),

Applications 2-Amino-N-benzylbenzamide can be used for drug discovery and pharmaceutical manufacturing.
References Amini-Rentsch, L., et.al., Ind. Eng. Chem. Res., 58, 10164-10171, (2019);

Applications 1,3-Dimethyl-2-nitrobenzene is an aromatic compound that is present as a contaminant in agricultural water sources. 1,3-Dimethyl-2-nitrobenzene is also a derivative of Xylene (X749400), an aromatic hydrocarbon that is widely used in the petrochemical industry.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Chen, C., et al.: J. Air Was. Manag. Ass., 55, 1487 (2005); Li, P.,e t al.: Bull. Env. Cont. Toxicol., 69, 59 (2002)

Applications 2-amino-3-hydroxy-3-phenylpropanoic acid (cas# 7695-56-9) is a useful research chemical.

Applications 4-[[[(1,1-Dimethylethyl)diphenylsilyl]oxy]methyl]-2,2-dimethyl-1,3-dioxolane is an intermediate in the synthesis of 1,2-Dioleoyl-rac-glycerol (D482175), which is an analog of 1,3-Dioleoylglycerol (D484210) which is used in the synthesis of amphiphilic gadolinium complexes as MRI contrast agents.
References Accardo, A., et. al.: J. Mater. Chem. B., 1, 617 (2013)

Applications o-Chloromethyltoluene is a building block that has been used in the preparation of fenarimol analogs showing curative activity in an experimental model of Chagas disease.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Keenan, M., et. al.: J. med. Chem., 56, 10158 (2013)

Applications 1,2,3-Trimethoxybenzene can be used for RSM-optimised slow pyrolysis of rice husk for bio-oil production.
References Das, S., et.al.: Energy, 225, 120161, (2021);

Applications An intermediate for the preparation of Terbutaline.

Applications A compound used in anti-corrosive coating material for the prevention of corrosion in metals.
References Weng, C. et al.: Chem. Mat., 22, 2075 (2011);

Applications 4-Cyanocyclohexanone is used to prepare nicotinamides as PDE4 D isoenzymes inhibitors. It is also used as an anthranilic acid replacement in niacin receptor agonist.
References Marfat, A., et al.: PCT Int. Appl. (1998), WO 9845268 A1 19981015; Schmidt, D., et al.: Bioorg. Med. Chem. lett., 20, 3426 (2010)

Applications Ethyl 3,5-dichloro-4-hydroxybenzoate (cas# 17302-82-8) is a useful research chemical.

Applications Bis(2,4,5-tribromophenyl)iodonium Hydrogen Sulfate is an intermediate in the synthesis of 2,2',4,4',5,6'-Hexabromodiphenyl ether (H290745), which is a hepatotoxic polybrominated diphenyl ester (PBDE) that is commonly used as a flame retardant. 2,2',4,4',5,6'-Hexabromodiphenyl ether is also sometimes found in food and meats as well, posing a significant risk to humans (especially during pregnancy) and/or animals that consume it. One of the new POPs under the Stockholm Convention
References Johnson, P., et al.: Sci. Total Environ., No vol. given, 445 (2013); Scott, L., et al.: Organo. Comp., 74, 1109 (2012); Zhao, Y., et al.: Env. Sci. Tech., 47, 5939 (2013)

Applications 3-Hydroxycyclohexane-1-carboxylic acid