Benzamides

4-Bromo-3,5-dihydroxybenzamide is a versatile building block that can be used as a reagent or as an intermediate in the synthesis of other compounds. It can also be used as a research chemical. 4-Bromo-3,5-dihydroxybenzamide has shown to be useful for the synthesis of complex organic compounds and is an excellent starting point for the preparation of novel scaffolds. This compound is also useful for making high quality products.

3,3'-Diaminobenzidine (DAB) is an organic compound derived from benzidine. It is the precursor to the synthetic fibre polybenzimidazole (PBI), which have high thermal and oxidative stability properties. DAB is water-soluble as the tetrahydrochloride salt and is used in immunohistochemical staining of nucleic acids and proteins. Research in Alzheimer's disease, Aβ protein amyloid plaques are targeted by a primary antibody, and subsequently by a secondary antibody, which is conjugated with a peroxidase enzyme. This will bind DAB as a substrate and oxidize it, producing an easily observable brown colour. 3,3’-Diaminobenzidine is also available as the tetrahydrochloride salt and the tetrahydrochloride hydrate.

4-Methoxybenzamide is a small molecule that has been shown to have anticancer activity in vitro and in vivo. It is a hydroxylated benzamide with an intramolecular hydrogen bond, which allows it to selectively bind to DNA at the C4' position of cytosine. The compound's anticancer effects are due to its ability to inhibit the transcription of genes involved in cancer cell proliferation and its ability to induce apoptosis via caspase activation. 4-Methoxybenzamide has been shown to be synergistic when used with other chemotherapeutics, such as cisplatin, doxorubicin or 5-fluorouracil. This drug also inhibits the uptake of these drugs by cancer cells, limiting their therapeutic effects on healthy tissues.

2,6-Difluoroaniline is a chemical compound that can be used as an industrial solvent in the production of cyclohexane. 2,6-Difluoroaniline has been used to produce amides and for clinical chemistry. It is also a reagent for the conversion of alcohols to amides. This chemical was shown to react with water vapor at an optimal temperature of approximately 60°C and pressure of approximately 100 kPa. 2,6-Difluoroaniline is industrially produced by the fluorination of fluoroethane using sodium carbonate or trifluoromethanesulfonic acid. The molecule has been explored for its apoptosis pathway inhibiting effects in covid-19 pandemic influenza virus

4-Bromo-2-chloroaniline (4BCA) is an exciplex that forms in the presence of hydrogen peroxide and chloride ions. It is unreactive with fluconazole and other related molecules, but is able to photoreduce hydrogen peroxide. The molecular mechanism of 4BCA is a result of its ability to form a covalent bond with DNA containing pyrimidine bases. This reaction results in the formation of pyrimidine dimers, which can lead to cell death through the inhibition of DNA synthesis and repair. 4BCA has been shown to be effective against cancer cells at high concentrations, but does not affect healthy cells. The effectiveness against cancer cells may be due to the fact that this exciplex reacts with uv irradiation and irradiation, which leads to a higher concentration of reactive oxygen species (ROS).

Dithio-2,2'-bis(N-methylbenzamide) is a chlorphenesin and benzyl alcohol combination that also contains pyrithione, benzyl chloride and benzalkonium chloride. It is a microbicide that inhibits the growth of bacteria by reacting with their cell membranes. Dithio-2,2'-bis(N-methylbenzamide) is used in cosmetics as a preservative, and has been shown to have antimicrobial properties against the section Micrococcus luteus. This product also contains imidazolidinyl urea as an anti-fungal agent.

2,4,6-Tribromo-3-nitroaniline is a brominating agent that can produce hydrogen peroxide. It is prepared by the reaction of hydrochloric acid with 2,4,6-tribromoaniline. The bromination of 2,4,6-tribromo-3-nitroaniline produces 4 equivalents of hydrogen peroxide.