Naphthalenes

1,2-Naphthoquinone is a reactive chemical that binds to DNA. It has been shown to inhibit the growth of cultured tumor cells in a genotoxic and cytotoxic manner. 1,2-Naphthoquinone inhibits the activity of many enzymes and has been used in pharmacological experiments on animal models. It is also used as a reagent for organic synthesis and as an intermediate for the production of other chemicals. The redox potential of 1,2-naphthoquinone can be determined by titration calorimetry.

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2-(Bromomethyl)naphthalene is a chemical that has been studied extensively for its ability to inhibit the growth of cancer cells. It binds with high affinity to the mitochondrial membrane potential and inhibits the production of ATP, leading to cell death. 2-(Bromomethyl)naphthalene has also been shown to produce reactive oxygen species (ROS), which can also induce tumor cell death. This compound has been used in a variety of biological samples, including urine samples, which have shown promising results. A potential target for this drug is an enzyme called hydrolysis, which may be found at higher concentrations in tumor cells. The proposed reaction mechanism is shown below: 2- (bromomethyl) naphthalene + H 2 O → bromide ion + 2- (hydroxymethyl) naphthalene The kinetic data and diphenyl sulfoxide are unknown at this time.